Protein Alignment GRIA3 and Ir7e

DIOPT Version :10

• Sequence 1: NP_000819.4
• Gene: GRIA3 / 2892
• HGNCID: 4573
• Length: 894
• Species: Homo sapiens
• Sequence 2: NP_001138176.1
• Gene: Ir7e / 7354417
• FlyBaseID: FBgn0259189
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 58/332 - (17%)
• Similarity: 120/332 - (36%)
• Gaps: 98/332 - (29%)

Human   550 PLAYEIWMCIVFAYIGVSVVLFLV----------SRFSPYEWHLEDNNEEPRDPQSPPDPPNEFG 604
            |...:|||.|: ..:.:|.::.|:          |||
  Fly   325 PYRLQIWMGIL-GVVALSALIQLIVGRMLRERMGSRF---------------------------- 360

Human   605 IFNSLWFSLG-AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL----------TV 658
                 |.:|. .|:.......|||.:.|:...:...:||||.:.|...|...:          |:
  Fly   361 -----WLNLELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLLYHLIRTHQLNRWPQTI 420

Human   659 ERMV--------SPI--ESAEDLAKQTEIAYGTLDSGSTKE--FFRRSKIAVYEKMWSYMKSAEP 711
            |.:|        :||  |..:::.....:.:..|::.|..:  :|    :....::..::.::..
  Fly   421 ESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDPLYF----LEANHQLRQHVTASAL 481

Human   712 SV---FTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSA 773
            .:   |.:.:||.|.: |..:|..|. .|....:.|..:.   ||.:.             |.|.
  Fly   482 DIFIHFNRLSADKVHQ-RGEQGSGAH-FEIVPEDIISMQL---TMYLA-------------KHSF 528

Human   774 LRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLA 838
            |.:.:|..::.:...||| .:.::|     |.......::.....|....:..:|.:::.||.:.
  Fly   529 LIDQLNEEIMWMRSVGLL-SVWSRW-----ELSESYLRNEQSFQVLGTMELYAIFLMVLVGLIVG 587

Human   839 MMVALIE 845
            ::|.::|
  Fly   588 LLVFILE 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRIA3	NP_000819.4	PBP1_iGluR_AMPA_GluR3	35..409	CDD:380610
		PBP2_iGluR_AMPA	422..805	CDD:270433	51/290 (18%)
Ir7e	NP_001138176.1	Periplasmic_Binding_Protein_Type_2	218..>313	CDD:473866