DRSC/TRiP Functional Genomics Resources

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Protein Alignment GRIA3 and Ir60a

DIOPT Version :10

Sequence 1:NP_000819.4 Gene:GRIA3 / 2892 HGNCID:4573 Length:894 Species:Homo sapiens
Sequence 2:NP_611901.1 Gene:Ir60a / 37881 FlyBaseID:FBgn0034994 Length:716 Species:Drosophila melanogaster


Alignment Length:150 Identity:35/150 - (23%)
Similarity:65/150 - (43%) Gaps:27/150 - (18%)


- Green bases have known domain annotations that are detailed below.


Human   162 VYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERI 226
            :|.:......|.:|.||:|.....:::.: .:..::||..|::|  :.|.|....||     .||
  Fly   553 IYAFPNNVFSSPVQMIMKAGFPFLFEMNS-IIRLMRDVGIFQKI--DADFRYNNTYL-----NRI 609

Human   227 NTILEQ-----VVILGKHSRGYHYML------ANLGFTDILLERVMHGGANITGFQIVNNENPMV 280
            |.:..|     :|:..:|.:|..::|      |.|.|   :.|.::|....    |:|:......
  Fly   610 NKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTF---IGELIIHRWRT----QLVSTSEQQD 667

Human   281 QQFIQRWVRLDEREFPEAKN 300
            ::..:|..|...|: ||..|
  Fly   668 RRSDKRRRRRRRRK-PEKDN 686

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GRIA3NP_000819.4 PBP1_iGluR_AMPA_GluR3 35..409 CDD:380610 34/149 (23%)
PBP2_iGluR_AMPA 422..805 CDD:270433
Ir60aNP_611901.1 None
Blue background indicates that the domain is not in the aligned region.

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