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Protein Alignment GRIA2 and Ir85a

DIOPT Version :9

Sequence 1:	NP_000817.5	Gene:	GRIA2 / 2891	HGNCID:	4572	Length:	883	Species:	Homo sapiens
Sequence 2:	NP_649833.1	Gene:	Ir85a / 41052	FlyBaseID:	FBgn0037630	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	69/373 - (18%)
Similarity:	129/373 - (34%)	Gaps:	94/373 - (25%)

- Green bases have known domain annotations that are detailed below.

Human   494 DIA-----IAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 553
            |:|     :.|.|.....|..:..::.    .:.:::.| .|:.|..::........:|..|:.:
  Fly   272 DVAMNIRFLVPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFWNIFRSFGSLVWALILVS 331

Human   554 YIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLS 618
            .:..:|..:::.                        :|.|......|: ||.......|.|.. |
  Fly   332 VLVANVFCYILK------------------------SEVGRVPMQLFA-GALTMPMTQIPPNH-S 370

Human   619 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLS----------KQTEIAYGTLDS 673
            .|:....|.:|.|:|.|::..||.:.:..:..:..|.....|:          :..:.....|..
  Fly   371 IRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTL 435

Human   674 GSTKEF-FRRSKIAVFD-KMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYL---LESTMNEYI 733
            |...|. .|...:.|.| :|:..||:.:.. |.......:||.:.:...:.:|   |...||..:
  Fly   436 GHKHESRIREQMLEVSDTQMYEMMRNNDIR-FAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCL 499

Human   734 EQRKPCDTMKVG----GNLDSKGYGIATPKGSSLRTP------------VNLAVLKLSEQGVLDK 782
            ........:..|    |.||           |.:|:.            :|.|.:|   .||  |
  Fly   500 VPFHAVYIVPYGSPYLGFLD-----------SLIRSSHEFGFERYWDRIMNSAFIK---SGV--K 548

Human   783 LKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLV 830
            :.|:         .:.||:.|.. .|.|.:...||.:.:.|:|:|.:|
  Fly   549 VVNR---------RRGSGNDEPV-VLKLQHFHAVFALWLVGIGMACIV 586

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.