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Protein Alignment GRIA2 and Ir7g

DIOPT Version :9

Sequence 1:	NP_000817.5	Gene:	GRIA2 / 2891	HGNCID:	4572	Length:	883	Species:	Homo sapiens
Sequence 2:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	98/547 - (17%)
Similarity:	172/547 - (31%)	Gaps:	180/547 - (32%)

- Green bases have known domain annotations that are detailed below.

Human   207 VILDCERDK-----------VNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGF 260
            |:|.|.|..           :.:.||.:|.        ..::..||      ...:..|......
  Fly    49 VVLSCRRPSPMNFYRNIMQLLYESVDTMIV--------QLVLVELG------RPRRIAGPRTHNL 99

Human   261 QIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKY--------TSALTYDAVQVMTEAFRNLRKQ 317
            .:||..|:|:...|..::         |.:.|.:|        .:.:.:|...|....:|:   |
  Fly   100 LLVDSLDALLDIEIHTYT---------AQSDTSEYYFIFLQQRDALIPHDMQGVFAYCWRH---Q 152

Human   318 RI--EISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKT 380
            .|  .:..:.:.|..|.:...|:..|          |..        |....|||..:.
  Fly   153 LINCNVMTQSSGGQVLLHTYFPYAPG----------QCN--------DSQPTRINMFLG------ 193

Human   381 NGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGY 445
                  ..|...|       ..||  ....|....::|.....||::      ::.||.....|.
  Fly   194 ------ESWKHRD-------YFPS--KLHNLNGCPLIVLARKVSPFL------DLDEGQRELRGL 237

Human   446 CVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVI 510
            ...|..|:::...|..:.:.:.|   ..::..|.....::.:||..:    ||.|.|..||:. |
  Fly   238 EGRLLQELSRRMNFSIQFSGLQD---QLKNRTTWTEKQLLQKLVQER----IAHLAIGYVRKR-I 294

Human   511 DFSK------PFMSLGI--SIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRF 567
            .::.      |..|..:  .:::.....:...::||  |.....|:|:||:::.:|.:..|. |
  Fly   295 QYATNLTPVFPHYSNRVVGCLLLNAHNLTSLEIWSF--PFQALTWICLVFSFLSISCLALLHXR- 356

Human   568 SPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQ-GCDIS-PRSLSGRIVGGVWWFFT 630
                                     |..:.|...|..:... |..|. |...|.:::...|..|.
  Fly   357 -------------------------GAGDRLALVLAVYAASLGLPIDPPERPSLQLLFASWLIFG 396

Human   631 LIIISSYTANLAAFL--------------------------TVERMVSPIESAEDL--------- 660
            ||:.|.|:|.|...|                          |..:.:..:.|.:||
  Fly   397 LIVRSMYSALLFFILRYHLHQRLPGNLQDLTHGDYAAVMGRTTLQDLREVPSLQDLLGLKSVIVT 461

Human   661 SKQTEIAYGTLD-------SGSTKEFF 680
            |::.|....|||       :||...||
  Fly   462 SEREEEVLRTLDRCTLREGAGSHPLFF 488

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.