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Protein Alignment GRIA2 and Ir7c

DIOPT Version :9

Sequence 1:	NP_000817.5	Gene:	GRIA2 / 2891	HGNCID:	4572	Length:	883	Species:	Homo sapiens
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	94/472 - (19%)
Similarity:	181/472 - (38%)	Gaps:	99/472 - (20%)

- Green bases have known domain annotations that are detailed below.

Human   416 VVVTTILESPYVMMKKNHEMLEGNERY--EGYCVDLAAEIAKHCGFKYKLT---------IVGDG 469
            :||.|....|||:::.:.:...|...:  ||.   :...:|:...|..||.         |:.||
  Fly   216 MVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPDG 277

Human   470 KYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 534
            .:          .|::..:|.|:.::.......:..|.:::..|..:.|..|.:::.......|
  Fly   278 NF----------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP- 331

Human   535 VFSFLDPLAYEIWMCIVFAYI-GVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSL 598
            :.....|..|.||.||:.:.| |..::..|.....|   .......||..:..        |..:
  Fly   332 MGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALP---GLRNLVLGRRNRLP--------FMGM 385

Human   599 WFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES-AEDL 660
            |.||  |..:     .:|:....|.:..:|...|||:.::||..|...|....|.|||:| :|.|
  Fly   386 WASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVL 445

Human   661 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSV---FVRTTAEGVARVR--KSKGK 720
            :|..|              ||     :...:.|..:.:.|:.   .|.:..|.:.|:|  ...|.
  Fly   446 AKDYE--------------FR-----ILPALRTIFKDSMPTTNFHAVLSLEESLYRLRDEDDPGI 491

Human   721 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATP-------------KGSSLRTPVNLAVL 772
            ...||:.|:|::..:..|           :|.:....|             ..|..:..::..::
  Fly   492 TVALLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHSYFKRRIDRLIM 545

Human   773 KLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCY 837
            .:...|::.:.: |.:.|:.:..:|....:.|  .||:..::|:|....|...:|::|.::|...
  Fly   546 AMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCAGLYLVALIVFILEILT 607

Human   838 KSRAEAKRMKVAKNAQN 854
            .:.   :|::.|.|..|
  Fly   608 TNH---RRLRRAFNVIN 621

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.