DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hmcn1 and dpr9

DIOPT Version :9

Sequence 1:NP_001258221.1 Gene:Hmcn1 / 289094 RGDID:1564772 Length:5635 Species:Rattus norvegicus
Sequence 2:NP_001287332.1 Gene:dpr9 / 2768670 FlyBaseID:FBgn0038282 Length:602 Species:Drosophila melanogaster


Alignment Length:728 Identity:143/728 - (19%)
Similarity:229/728 - (31%) Gaps:303/728 - (41%)


- Green bases have known domain annotations that are detailed below.


  Rat  1789 KLVIAQAQVSDTGLYQ---CVATNVAGDRRKEFEVTVHVPPTIKSSDLPEKTVVRYKPVSLQCI- 1849
            ::.:.|.|...|.|.|   .|||:.|..:|:.     |:.|  :|:|.|        |.|..|| 
  Fly     5 QMEMRQQQHQRTNLRQRAAAVATSKARRQRQH-----HLQP--ESTDSP--------PYSTDCIR 54

  Rat  1850 ------------ANGIPNPSITWLKDDQPVNTAP----GNLRIQSSGRV---------------- 1882
                        .||.| |:..        ||:.    ||:...:|.|:                
  Fly    55 LWPGCGPTTADRVNGNP-PTCN--------NTSSSDIGGNISGNTSNRISCCSCNFGRQRALIML 110

  Rat  1883 --LQIAKALLEDAGRYTC---------------------VATNAAGEAHQHTQLHVHEPPSLDDG 1924
              |.:..||:...|.|..                     |..:|||..    :.....|..:|..
  Fly   111 SMLVVVMALMSGNGVYAAQRDSYNSKDMSSSNNALPNEGVGGSAAGAG----EAAAPGPTGIDGS 171

  Rat  1925 GKMLNESVVVNNPIQLECKATGSPVPVLTWYKDSHPLAGSTSATFLKRGQILEIGSAQISDAGIY 1989
            |...|.|  .||                   |:.||.|||.:|:         ..:|..:||.  
  Fly   172 GSGNNSS--GNN-------------------KNGHPAAGSGAAS---------ESAALTTDAS-- 204

  Rat  1990 KCVAINSAGATELFYSLQVHVPPSISGSSSMVEVVVNNLARLECEARGIPAPSLTWLKDGSPVSS 2054
                                 ..|:.|::::.               |||:.|   |...|..||
  Fly   205 ---------------------RSSVGGATTIT---------------GIPSSS---LHKASSASS 230

  Rat  2055 FSNGIQVLSGGRILALTSAQMSDTGRYTCVAVNAAGEKQRDFDLRVYAPPNIMGEEQNVSVLISQ 2119
            .:...|:.||....::...:..:.|.|              || :.::        :||:.|:.:
  Fly   231 NTFSSQLASGFHRNSIDLEEARNAGPY--------------FD-KAFS--------KNVTALLGK 272

  Rat  2120 TVELFCQSDAVPPPTLM----WFKDGRPLLKRPGLSISENGSVLMIEDAQAGDTGRYTCEATNVA 2180
            |..|.|:...:...|::    |.:.                     .|......||||       
  Fly   273 TAYLNCRVKNLGNKTMLLQVSWVRH---------------------RDIHLLTVGRYT------- 309

  Rat  2181 GKTEKNYNVNIWVPPSIYGSDELVQLTAIEGNLITLLCESSGIPPPNLTWKKKGSLVLADAAGRV 2245
                             |.||:  :..||.             .|....|               
  Fly   310 -----------------YTSDQ--RFRAIH-------------QPQTEDW--------------- 327

  Rat  2246 HILSGGRRLQISIAEKADAGLYTCVASNVAGIAKKEY-NLQVYIRPSIANSGSHRPEITVIRGRS 2309
                   .|||...:..|:|:|.|..|....::  .| :|.| :.||....|:  |::.:..|.:
  Fly   328 -------MLQIKYPQHRDSGIYECQVSTTPHMS--HYIHLNV-VEPSTEIIGA--PDLYIESGST 380

  Rat  2310 ISLECEVQGIPQPT--VTWMKD----GRPL-----SKGKGVEIL-DEG----RVLQLKNVHVSDT 2358
            |:|.|.:|..|:|.  :.|..:    ..|.     |...||.:: ::|    ..|.:|:...||:
  Fly   381 INLTCIIQNSPEPPAYIFWNHNNAFPSHPQIINYDSPRGGVSVVTNKGDTTTSFLLIKSARPSDS 445

  Rat  2359 GRYVCVAVNVAGMTDKRYDLSVHVPPSIIGNH----GVPENISVVEKSSVSLTCEASGIPLPSIT 2419
            |.|.|...|.     |...::|||...:  :|    |||.:.:....|:.|....:..:.:|...
  Fly   446 GHYQCNPSNA-----KPKSVTVHVLNGV--SHSVSRGVPSSNAARGTSASSPLAHSLSVCVPVCV 503

  Rat  2420 WLKDG---WPVSL 2429
            .|:.|   |..:|
  Fly   504 LLQLGACRWIAAL 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hmcn1NP_001258221.1 VWA_2 42..212 CDD:290253
I-set 520..608 CDD:254352
ig 524..606 CDD:278476
I-set 612..696 CDD:254352
Ig 626..696 CDD:299845
I-set 702..789 CDD:254352
Ig 716..789 CDD:299845
Ig 792..884 CDD:299845
IG_like 799..884 CDD:214653
I-set 890..977 CDD:254352
IGc2 903..967 CDD:197706
Ig 980..1071 CDD:299845
IG 994..1068 CDD:214652
I-set 1085..1167 CDD:254352
Ig 1086..1167 CDD:299845
I-set 1171..1258 CDD:254352
Ig 1188..1255 CDD:143165
Ig 1261..1357 CDD:299845
I-set 1267..1355 CDD:254352
I-set 1368..1448 CDD:254352
Ig 1380..1448 CDD:299845
IG 1460..1541 CDD:214652
IGc2 1470..1532 CDD:197706
IG_like 1557..1633 CDD:214653
Ig 1565..1632 CDD:143165
I-set 1645..1729 CDD:254352
Ig 1648..1725 CDD:299845
I-set 1752..1822 CDD:254352 10/35 (29%)
Ig 1754..1815 CDD:299845 9/28 (32%)
IG 1834..1915 CDD:214652 24/136 (18%)
IGc2 1843..1905 CDD:197706 21/117 (18%)
IG_like 1929..2008 CDD:214653 14/78 (18%)
IGc2 1935..1998 CDD:197706 12/62 (19%)
I-set 2012..2100 CDD:254352 17/87 (20%)
Ig 2021..2092 CDD:299845 13/70 (19%)
I-set 2111..2191 CDD:254352 13/83 (16%)
IGc2 2119..2181 CDD:197706 10/65 (15%)
I-set 2203..2286 CDD:254352 14/83 (17%)
IGc2 2210..2276 CDD:197706 10/65 (15%)
Ig 2299..2380 CDD:299845 23/96 (24%)
IG_like 2300..2380 CDD:214653 23/95 (24%)
I-set 2392..2474 CDD:254352 9/41 (22%)
IGc2 2400..2464 CDD:197706 7/33 (21%)
I-set 2478..2567 CDD:254352
IGc2 2493..2557 CDD:197706
I-set 2582..2663 CDD:254352
IGc2 2594..2653 CDD:197706
I-set 2681..2762 CDD:254352
Ig 2688..2762 CDD:299845
IG_like 2789..2865 CDD:214653
IGc2 2791..2855 CDD:197706
I-set 2879..2960 CDD:254352
Ig 2879..2950 CDD:299845
IG 2972..3052 CDD:214652
IGc2 2982..3042 CDD:197706
IG 3069..3147 CDD:214652
IGc2 3073..3137 CDD:197706
IG 3150..3241 CDD:214652
Ig 3150..3241 CDD:299845
Ig 3244..3338 CDD:299845
I-set 3252..3336 CDD:254352
I-set 3354..3430 CDD:254352
IGc2 3357..3420 CDD:197706
Ig 3433..3523 CDD:299845
IG_like 3443..3523 CDD:214653
IG_like 3535..3616 CDD:214653
IGc2 3543..3606 CDD:197706
I-set 3629..3709 CDD:254352
IGc2 3636..3699 CDD:197706
I-set 3713..3800 CDD:254352
Ig 3719..3795 CDD:299845
Ig 3823..3889 CDD:143165
I-set 3897..3984 CDD:254352
IGc2 3913..3974 CDD:197706
Ig 3993..4066 CDD:299845
IG_like 3994..4075 CDD:214653
IG_like 4085..4165 CDD:214653
IGc2 4092..4155 CDD:197706
Ig 4168..4258 CDD:299845
IG 4177..4256 CDD:214652
I-set 4260..4345 CDD:254352
IGc2 4274..4335 CDD:197706
IG_like 4356..4435 CDD:214653
IGc2 4364..4426 CDD:197706
I-set 4440..4526 CDD:254352
Ig 4440..4521 CDD:299845
TSP1 4533..4584 CDD:214559
TSP1 4589..4641 CDD:214559
TSP1 4646..4698 CDD:214559
TSP1 4703..4755 CDD:214559
TSP1 4760..4812 CDD:214559
TSP1 4817..4869 CDD:214559
G2F 4868..5092 CDD:214774
EGF_CA 5107..5146 CDD:214542
EGF_CA 5147..5190 CDD:284955
EGF_CA 5192..5229 CDD:214542
EGF_CA 5230..5263 CDD:238011
EGF_CA 5272..5313 CDD:284955
EGF_CA 5315..5354 CDD:214542
EGF_CA 5432..5471 CDD:214542
EGF_CA 5472..5508 CDD:214542
dpr9NP_001287332.1 Ig 263..361 CDD:299845 31/190 (16%)
IG_like 263..360 CDD:214653 30/188 (16%)
IG_like 371..464 CDD:214653 24/97 (25%)
IGc2 377..456 CDD:197706 21/83 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR23279
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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