DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ncam2 and DIP-epsilon

DIOPT Version :9

Sequence 1:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus
Sequence 2:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster


Alignment Length:434 Identity:105/434 - (24%)
Similarity:164/434 - (37%) Gaps:105/434 - (24%)


- Green bases have known domain annotations that are detailed below.


  Rat   117 FREVLSPQEFKQGEDAEVVCRVSSSPAPAVSWLY---------HNEEVTTIPDNRFAVLANNN-- 170
            |.:|:.......|.:.::.|.|.:..:..|:|::         ||..:|..|  |.:|..:.:  
  Fly    54 FTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNP--RISVTHDKHDK 116

  Rat   171 -----LQILNINKSDEGIYRCE-GRVEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAERGEEMT 229
                 |.|.|:.:.|.|.|.|: ..|.|:.:..|..::|..|:..|:.    |.:.....|:.:|
  Fly   117 HRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALT----SSDIIVREGDNVT 177

  Rat   230 LTCKASGSPDPAISWFR-NGKLIEENEKYILKGSNTE-LTVRNIINKDGGSYVCKATN------- 285
            |.|||.|||:|.|.|.| :|..|..|:...:....|: |.:..|.....|:|:|.|:|       
  Fly   178 LRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVS 242

  Rat   286 ---KAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLICEAEGEPVPEITWKRAIDGVTFSEGD 347
               |...|    |..:...||  ||.......|  :||.|..|..|.....|.|..|.: .:|..
  Fly   243 KRIKVSVD----FSPMVWIPH--QLVGIPIGFN--ITLECFIEANPTSLNYWTRENDQM-ITESS 298

  Rat   348 KSPDGRIEVKGQHGRSS------LHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAPKFVSN 406
            |.....|.     |..|      |.|.:|:.||.|.|.|.|.:..|        |::      .|
  Fly   299 KYKTETIP-----GHPSYKATMRLTITNVQSSDYGNYKCVAKNPRG--------DMD------GN 344

  Rat   407 QTMYYSWEGNPINISCDVKANPPASIHWRREKLVLPAKNTTHLKTHSVGRKMILE---IAPTSDN 468
            ..:|.|              :||.:        ..|...||..:|.:...::.|:   ..|.:.|
  Fly   345 IKLYMS--------------SPPTT--------QPPPTTTTLRRTTTTAAEIALDGYINTPLNGN 387

  Rat   469 DFGRYNCTATNRI---GTRFQEYILELADVP--------SSPRG 501
            ..|......||.:   |....:|:..|.::.        |||:|
  Fly   388 GIGIVGEGPTNSVIASGKSSIKYLSNLNEIDKSKQKLTGSSPKG 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706 18/77 (23%)
Ig strand B 130..139 CDD:409353 1/8 (13%)
Ig strand C 145..153 CDD:409353 3/16 (19%)
Ig strand C' 156..159 CDD:409353 1/2 (50%)
Ig strand D 162..167 CDD:409353 2/4 (50%)
Ig strand E 168..175 CDD:409353 2/13 (15%)
IgI_1_MuSK 209..298 CDD:409562 29/100 (29%)
Ig strand B 228..232 CDD:409562 2/3 (67%)
Ig strand C 241..245 CDD:409562 1/3 (33%)
Ig strand E 264..268 CDD:409562 2/4 (50%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 28/102 (27%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 3/7 (43%)
Ig strand C 331..337 CDD:409353 1/5 (20%)
Ig strand C' 340..343 CDD:409353 0/2 (0%)
Ig strand D 353..359 CDD:409353 1/5 (20%)
Ig strand E 362..368 CDD:409353 2/11 (18%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 1/9 (11%)
Ig_3 401..479 CDD:404760 13/80 (16%)
Ig strand B 418..422 CDD:409353 0/3 (0%)
Ig strand C 431..435 CDD:409353 0/3 (0%)
Ig strand E 458..462 CDD:409353 1/6 (17%)
Ig strand F 472..477 CDD:409353 0/4 (0%)
Ig strand G 486..489 CDD:409353 0/2 (0%)
FN3 496..588 CDD:238020 4/14 (29%)
fn3 594..678 CDD:394996
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 21/97 (22%)
Ig 69..139 CDD:143165 17/71 (24%)
IG_like 165..249 CDD:214653 26/83 (31%)
IGc2 172..237 CDD:197706 24/64 (38%)
IG_like 267..348 CDD:214653 26/102 (25%)
Ig 270..339 CDD:299845 22/74 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.000

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