DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ncam2 and DIP-delta

DIOPT Version :9

Sequence 1:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus
Sequence 2:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster


Alignment Length:448 Identity:104/448 - (23%)
Similarity:175/448 - (39%) Gaps:72/448 - (16%)


- Green bases have known domain annotations that are detailed below.


  Rat   201 IIVIVNVPPAIVMPQKSF-----NATAERGEEMTLTCKASGSPDPAISWFR---------NGKLI 251
            :|.:.|:...::|.:..|     |.|...|.:..|.|.........::|..         :..:|
  Fly    29 LIYMTNLVTHVMMDEPRFAQPIPNVTVAVGRDANLPCVVEHLGGYKVAWIHIDRQMILTIHRHVI 93

  Rat   252 EENEKY-ILKGSNTELT-VRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTS- 313
            ....:| |....||.|. |......|.|.|:|:........| ..:|||.|.|:||.:::..:| 
  Fly    94 SRIPRYSITYTDNTWLLHVNQAHQDDRGYYMCQVNTNPMISQ-VGYLQVVVPPNILDIESTPSSV 157

  Rat   314 ---ENGHVTLICEAEGEPVPEITWKRAIDGVTFSEGDKSPDGRIEVKGQ---HGRSSLHIRDVKL 372
               ||.::.:.|.|:|.|.|:|.|:|. ||...:         :|.|.:   :....|.:..|..
  Fly   158 AVRENQNINMTCRADGFPAPKIIWRRE-DGEEIA---------VEKKKKVLVYDADVLPLTKVSR 212

  Rat   373 SDSGRYDCEAASRI-GGHQRSMHLDIEYAPK-FVSNQTMYYSWEGNPINISCDVKANPPASIHW- 434
            ::.|.|.|.|.:.: ....:.:.||:|::|. :|.|| :..:..|..:.|.|..:|:|.|.|:| 
  Fly   213 NEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQ-LVGAPSGTDVTIDCHTEAHPKAIIYWV 276

  Rat   435 RREKLVLPAKN-TTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGT---RFQEYILELADV 495
            ....:|||:|. .|....:|....|.|.|......|||.|.|.:.|.:|.   ..:.|.:.|...
  Fly   277 YNSVMVLPSKKYKTDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPST 341

  Rat   496 PSSPRGVKIIELSQTTAKISFNK--PESHGGVPIHHYQVDV---------------KEVTSETWK 543
            ||.       :::.||.:...|.  |.|.... ....|.||               ......:..
  Fly   342 PSK-------QVTHTTVESRENNIIPSSRNDT-TKSLQTDVGYAMKNDLYPGSASSSSSGGSSSA 398

  Rat   544 IVRSHGVQTTVVLSSLEPNTTYEVRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHG 601
            ...|..:||:.:...:..|:     ::::..||.....|...:...|..|.:..|:.|
  Fly   399 ASSSSSMQTSALPGGVAGNS-----LSSMGSKGSLAIGKSTFYTERPPNEYAASSVAG 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706
Ig strand B 130..139 CDD:409353
Ig strand C 145..153 CDD:409353
Ig strand C' 156..159 CDD:409353
Ig strand D 162..167 CDD:409353
Ig strand E 168..175 CDD:409353
IgI_1_MuSK 209..298 CDD:409562 21/104 (20%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 0/3 (0%)
Ig strand E 264..268 CDD:409562 2/4 (50%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 1/2 (50%)
Ig 300..397 CDD:416386 26/104 (25%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 1/7 (14%)
Ig strand C 331..337 CDD:409353 2/5 (40%)
Ig strand C' 340..343 CDD:409353 1/2 (50%)
Ig strand D 353..359 CDD:409353 2/5 (40%)
Ig strand E 362..368 CDD:409353 1/5 (20%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 1/9 (11%)
Ig_3 401..479 CDD:404760 26/80 (33%)
Ig strand B 418..422 CDD:409353 1/3 (33%)
Ig strand C 431..435 CDD:409353 2/4 (50%)
Ig strand E 458..462 CDD:409353 2/3 (67%)
Ig strand F 472..477 CDD:409353 2/4 (50%)
Ig strand G 486..489 CDD:409353 0/2 (0%)
FN3 496..588 CDD:238020 17/108 (16%)
fn3 594..678 CDD:394996 2/8 (25%)
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 21/92 (23%)
Ig 145..238 CDD:416386 25/102 (25%)
Ig strand A 145..149 CDD:409353 2/3 (67%)
Ig strand A' 154..159 CDD:409353 1/4 (25%)
Ig strand B 165..172 CDD:409353 1/6 (17%)
Ig strand C 178..183 CDD:409353 2/4 (50%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 0/3 (0%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 1/7 (14%)
Ig 242..333 CDD:416386 28/91 (31%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 2/6 (33%)
Ig strand C 272..277 CDD:409353 2/4 (50%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 1/3 (33%)
Ig strand E 295..305 CDD:409353 3/9 (33%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 1/8 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.000

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