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Protein Alignment ANK3 and pyx

DIOPT Version :9

Sequence 1:	NP_066267.2	Gene:	ANK3 / 288	HGNCID:	494	Length:	4377	Species:	Homo sapiens
Sequence 2:	NP_612015.1	Gene:	pyx / 38037	FlyBaseID:	FBgn0035113	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	99/345 - (28%)
Similarity:	154/345 - (44%)	Gaps:	49/345 - (14%)

- Green bases have known domain annotations that are detailed below.

Human   419 LLKHGASIQAVTES-GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGE-TALHMAARSGQAEV 481
            ||||..:...|.:| |.||:|.|....:..|...|:..||.||..:.|.| |:||.||.|...|.
  Fly   118 LLKHYNADPNVADSRGRTPLHFACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKSVEC 182

Human   482 VRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHED 546
            :..|::..|.:.. ..:.::.||.:..:...|.|:.||:.||.||.......||||.::..|...
  Fly   183 ILLLLRRKASINI-GIEKRSALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAK 246

Human   547 VAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQ 611
            ....||.|.|.             |.:::|:                 ||  :|.||:||..|..
  Fly   247 CVQLLLSHNAD-------------VRSQFGE-----------------GK--VTALHLAAENDYV 279

Human   612 KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLA--AQE 674
            :.|.|||:..|.......:..||||:|.....:.....|:.|||:.|||.|.|..::|.|  .|.
  Fly   280 ECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGRTALHAAIVKQS 344

Human   675 GHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCH 739
            ..:|..:.||...|:||.::..|.||||:||..:..:.....:..||.:.|:|.
  Fly   345 RSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSSCVYTFIEHGADITARTD----------- 398

Human   740 YGNIKIVNFLLQHSAKVNAK 759
             |.:..::|:::.:.::..|
  Fly   399 -GRVSALSFIVRRTPEIIPK 417

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.