DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ANK3 and Ank3

DIOPT Version :9

Sequence 1:	NP_066267.2	Gene:	ANK3 / 288	HGNCID:	494	Length:	4377	Species:	Homo sapiens
Sequence 2:	XP_038954762.1	Gene:	Ank3 / 361833	RGDID:	620157	Length:	4329	Species:	Rattus norvegicus

Alignment Length:	4385	Identity:	3862/4385 - (88%)
Similarity:	4068/4385 - (92%)	Gaps:	65/4385 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAHAASQLKKNRDLEINAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV 65
            |||||||||||||||||||||.|||:|||||||||||||||||||||||||||||||||||||||
  Rat     1 MAHAASQLKKNRDLEINAEEETEKKKKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV 65

Human    66 DINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
            |:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 DVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130

Human   131 ANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195
            ||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||
  Rat   131 ANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195

Human   196 DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAA 260
            ||||||||||||||||||||||||||||||.|||:||||||||||||||||||||||||||||||
  Rat   196 DTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKSGFTPLHIAAHYGNINVATLLLNRAAA 260

Human   261 VDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 VDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325

Human   326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 PILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKK 390

Human   391 ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH 455
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
  Rat   391 ANPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHH 455

Human   456 GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ 520

Human   521 QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLL 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||
  Rat   521 QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLL 585

Human   586 QKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
  Rat   586 QKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSL 650

Human   651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEV 715
            ||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||
  Rat   651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEV 715

Human   716 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN 780
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   716 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN 780

Human   781 VLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLD 845
            ||||||||||||||||||||.|||||||||||||||:||||.|||||:|||||||||||||||||
  Rat   781 VLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVTEEIMTTTTITEKHKMNVPETMNEVLD 845

Human   846 MSDDEVRKANAPEMLSDGEYISDVEEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSLGAR 910
            ||||||.||:|||.|||||||||.||||||:||||||||||||||||||||||||||:|||||||
  Rat   846 MSDDEVGKASAPEKLSDGEYISDGEEGEDAITGDTDKYLGPQDLKELGDDSLPAEGYVGFSLGAR 910

Human   911 SASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNL 975
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
  Rat   911 SASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLPFTREFDSDSLRHYSWAADTLDNVNL 975

Human   976 VSSPIHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGE 1040
            ||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   976 VSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGE 1040

Human  1041 GLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLTELLN 1105
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
  Rat  1041 GLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLSELLN 1105

Human  1106 GMDEELDSPEELGKKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGA 1170
            |||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1106 GMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGA 1170

Human  1171 LTKRIRVGLQAQPVPDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYK 1235
            |||||||||||||||:|.|||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1171 LTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYK 1235

Human  1236 GDTTPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLATQ 1300
            |||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
  Rat  1236 GDTTPSLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQ 1300

Human  1301 LYRELICVPYMAKFVVFAKMNDPVESSLRCFCMTDDKVDKTLEQQENFEEVARSKDIEVLEGKPI 1365
            |||||||||||||||||||.||||||||||||||||:||||||||||||||||||||||||||||
  Rat  1301 LYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPI 1365

Human  1366 YVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVC 1430
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat  1366 YVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKVRDTSQEPCGRLSFLKEPKTTKGLPQTAVC 1430

Human  1431 NLNITLPAHKKETESDQDDEIEKTDRRQSFASLALRKRYSYLTEPGMIERSTGATRSLPTTYSYK 1495
            ||||||||||||||||||||.||.||||||.||||||||||||||.|||||:|..||||||||:|
  Rat  1431 NLNITLPAHKKETESDQDDEAEKADRRQSFTSLALRKRYSYLTEPSMIERSSGTARSLPTTYSHK 1495

Human  1496 PFFSTRPYQSWTTAPITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKSTLGASTTSS 1560
            |||||||||||||.|:|||||||||  |||||.||||||||||||||||||||||||||||||||
  Rat  1496 PFFSTRPYQSWTTTPLTVPGPAKSG--SLSSSPSNTPSASPLKSIWSVSTPSPIKSTLGASTTSS 1558

Human  1561 VKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAVTEATPLKGLASNSTFSSRTS 1625
            ||||||||||||||||:||||:||.|.||||.||:||||.|.|.:|||||:||||.|||.|||||
  Rat  1559 VKSISDVASPIRSFRTISSPIRTVASPSPYNTQVASGTLGRVPTITEATPIKGLAPNSTLSSRTS 1623

Human  1626 PVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIITSAAPLISSPLKSVVSPVKSAVDVIS 1690
            |||||||||||||||||||||||:||.|||||||||||||||||||||||||||||.|||.||||
  Rat  1624 PVTTAGSLLERSSITMTPPASPKANITMYSSSLPFKSIITSAAPLISSPLKSVVSPTKSAADVIS 1688

Human  1691 SAKITMASSLSSPVKQMPGHAEVALVNGSISPLKYPSSSTLINGCKATATLQEKISSATNSVSSV 1755
            :||..|||:||||:|||.|||||||||||:|||||||||.||||||||||||:|||:|||:||||
  Rat  1689 TAKAAMASTLSSPLKQMSGHAEVALVNGSVSPLKYPSSSALINGCKATATLQDKISTATNAVSSV 1753

Human  1756 VSAATDTVEKVFSTTTAMPFSPLRSYVS-AAPSAFQSLRTPSASALYTSLGSSISATTSSVTSSI 1819
            ||||.|||||..|||||||||||||||| ||||||||||.|||||||||||.|::.|||||||||
  Rat  1754 VSAAPDTVEKALSTTTAMPFSPLRSYVSAAAPSAFQSLRAPSASALYTSLGPSVAVTTSSVTSSI 1818

Human  1820 ITVPVYSVVNVLPEPALKKLPDSNSFTKSAAALLSPIKTLTTETHPQPHFSRTSSPVKSSLFLAP 1884
            |||||||||||||||||||||||||.||||||||||||||||||.|||||:|||||||||||||.
  Rat  1819 ITVPVYSVVNVLPEPALKKLPDSNSLTKSAAALLSPIKTLTTETRPQPHFNRTSSPVKSSLFLAS 1883

Human  1885 SALKLSTPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEEKPFQPELPKEGRIDDEEPFKIVE 1949
            ||||.|.|||||||||||||||||||||||||||||||||||||||.:||:||||||||||||||
  Rat  1884 SALKPSVPSSLSSSQEILKDVAEMKEDLMRMTAILQTDVPEEKPFQTDLPREGRIDDEEPFKIVE 1948

Human  1950 KVKEDLVKVSEILKKDVCVDNKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQAAASQSPSLPE 2014
            |||||||||||||||||||::||.||||||||||||||||.||||||||||| |||||.:|||||
  Rat  1949 KVKEDLVKVSEILKKDVCVESKGPPKSPKSDKGHSPEDDWTEFSSEEIREAR-QAAASHAPSLPE 2012

Human  2015 RVQVKAKAASEKDYNLTKVIDYLTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLKPAIALQEHKL 2079
            ||..||        |||:||||||||||||||||||||||:|||:|||||||:||||:|||||||
  Rat  2013 RVHGKA--------NLTRVIDYLTNDIGSSSLTNLKYKFEEAKKEGEERQKRILKPAMALQEHKL 2069

Human  2080 KMPPASMRTSTSEKELCKMADSFFGTDTILESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSA 2144
            ||||||||.||||||||||||||||||.|||||||||||||||||||||||||||||||||||||
  Rat  2070 KMPPASMRPSTSEKELCKMADSFFGTDAILESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSA 2134

Human  2145 ESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMELEPKPTT 2209
            ||||||||||||||||||||||||||||||||:||.|::||:|||:||||||.|||||||||||.
  Rat  2135 ESTGPKPLFHEVPIPPVITETRTEVVHVIRSYEPSTGEIPQSQPEDPVSPKPPPTFMELEPKPTA 2199

Human  2210 SSIKEKVKAFQMKASSEEDDHNRVLSKGMRVKEETHITTTTRMVYHSPPGGEGASERIEETMSVH 2274
            .|||||||||||||||||:||:||||||||||||||||||||||||||||.|.||||||||||||
  Rat  2200 PSIKEKVKAFQMKASSEEEDHSRVLSKGMRVKEETHITTTTRMVYHSPPGSECASERIEETMSVH 2264

Human  2275 DIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQ 2339
            |||||||||||||||||||||||||:||||.||||||||||||||||||||||||||||||||||
  Rat  2265 DIMKAFQSGRDPSKELAGLFEHKSAMSPDVAKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGNQ 2329

Human  2340 AEPTEVIIRETKKHPEKEMYVYQKD-LSRGDINLKDFLPEKHDAFPCSEEQGQQEEEELTAEESL 2403
            ||||||||||||||||||:.||||| ||||:||||||||||||||||.||||||||||..|||||
  Rat  2330 AEPTEVIIRETKKHPEKEVSVYQKDLLSRGNINLKDFLPEKHDAFPCPEEQGQQEEEEFAAEESL 2394

Human  2404 PSYLESSRVNTPVSQEEDSRPSSAQLISDDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKML 2468
            ||||||||||||.|||||||||||||:|||||||||||||||:||||||||:|||||||||||||
  Rat  2395 PSYLESSRVNTPGSQEEDSRPSSAQLLSDDSYKTLKLLSQHSVEYHDDELSDLRGESYRFAEKML 2459

Human  2469 LSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKIATAPKKEILSKIYKDVSENGVGKVSKD 2533
            |||||||||||||||||||||||||||||||||||||:||||.|||||||||||||||:|:||||
  Rat  2460 LSEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSREKVATAPPKEILSKIYKDVSENGIGRVSKD 2524

Human  2534 EHFDKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDK 2598
            |||:|:|||||:||||.|||.|||..:|||||||||||:||||||||||||||||||||||||||
  Rat  2525 EHFEKLTVLHYAGNVSGPKHTMWMHLSEDRLDRGREKLMYEDRVDRTVKEAEEKLTEVSQFFRDK 2589

Human  2599 TEKLNDELQSPEKKARPKNGKEYSSQSPTSSSPEKVLLTELLASNDEWVKARQHGPDGQGFPKAE 2663
            ||||||||||||||.||||||||||||.|||||||| ||||||||||||||||.||||||.|:||
  Rat  2590 TEKLNDELQSPEKKPRPKNGKEYSSQSSTSSSPEKV-LTELLASNDEWVKARQRGPDGQGVPQAE 2653

Human  2664 E-KAPSLPSSPEKMVLSQQTEDSKSTVEAKGS-ISQSKAPDGPQSGFQLKQSKLSSIRLKFEQGT 2726
            : ||||..|||||.|.|||.||.:...|||.: |:||:..:|||||||||||||||||||||||.
  Rat  2654 DRKAPSGSSSPEKRVPSQQIEDGQPPEEAKRTVIAQSRGQEGPQSGFQLKQSKLSSIRLKFEQGA 2718

Human  2727 HAKSKDMSQEDRKSDGQSRIPVKKIQESKLPVYQVFAREKQQKAIDLPDESVSVQKDFMVLKTKD 2791
            .|||||  .|::..||.|||||||.||:|||.:..|||||||||:|.|:|.:|||.|.::.  :.
  Rat  2719 RAKSKD--HEEKNLDGPSRIPVKKTQENKLPTHPGFAREKQQKAVDPPEEKMSVQNDVLIF--RP 2779

Human  2792 EHAQSNEIVVNDSGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACHITSDLATRGPWDKKVFRTWE 2856
            ||.:|:|:||::|||.:.|..||||.|||.||.|.|||.:|.||.|||||.|:||||:|||||||
  Rat  2780 EHGKSSEMVVSESGSSDGKSHRTEMLSKATPDFFPEQQVEDSACPITSDLETKGPWDRKVFRTWE 2844

Human  2857 SSGATNNKSQKEKLSHVLVHDVRENHIGHPE-SKSVDQKNEFMSVTERERKLLTNGSLSEIKEMT 2920
            ||||.|||:|||:||||||||:||:|:|||: |::.|.||:||.|||||.|:||||||||||||:
  Rat  2845 SSGANNNKAQKEQLSHVLVHDIRESHVGHPDSSENGDPKNDFMYVTEREHKMLTNGSLSEIKEMS 2909

Human  2921 VKSPSKKVLYREYVVKEGDHPGGLLDQPSRRSESSAVSHIPVRVADERRMLSSNIPDGFCEQSAF 2985
            |||||||||||||:|||||.|...|| |.|||||||.||.|:||.|||||||||||||.|||:.|
  Rat  2910 VKSPSKKVLYREYMVKEGDLPSSTLD-PPRRSESSAASHTPIRVTDERRMLSSNIPDGICEQTTF 2973

Human  2986 PKHELSQKLSQSSMSKETVETQHFNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPD 3050
            ||.:|||::|:.|:||..||:||||||:||||||||:|||||.||||||||.|:|||||||||||
  Rat  2974 PKQDLSQRVSRPSVSKGAVESQHFNSIDDEKVTYSEMSKVSKRQSYVGLCPALDETETSPTKSPD 3038

Human  3051 SLEFSPGKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVK 3115
            ||||||||:|||||||||..:|||||      .|||||||||||||||||||||||||:||||||
  Rat  3039 SLEFSPGKDSPSSDVFDHGSMDGLEK------AEGGKEIKTLPVYVSFVQVGKQYEKELQQGGVK 3097

Human  3116 KIISQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYE 3180
            ||||||||||||.||||||.|||||||||||||||||||||||||||||||||||||||||||||
  Rat  3098 KIISQECKTVQEARGTFYTARQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEEVSYE 3162

Human  3181 FTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAVEREMPNDVSKDSNQRPK 3245
            |||||||||||:|||:||||||||||.||||:.|:..|:|     ..||:|...||||||.||||
  Rat  3163 FTSKTPDSLIAFIPGQPSPIPEVSEEEEEEEEPKAAPLRQ-----VPVEKETDRDVSKDSVQRPK 3222

Human  3246 NNRVAYIEFPPPPPLDADQIESDKKHHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQPPSPVPP 3310
            .||||||||||||||||||:||||||.|||::||||:||:||||.||||||||||||||||||||
  Rat  3223 CNRVAYIEFPPPPPLDADQMESDKKHEYLPDREVDMMEVSLQDESDKYQLAEPVIRVQPPSPVPP 3287

Human  3311 GADVSDSSDDESIYQPVPVKKYTFKLKEVDDEQKE--KPKASAEKASNQKELESNGSGKDNEFGL 3373
            |||.|:||||||:|||.||||||||||.||:.||:  |.|.:..|||||||:|||  ||::|  .
  Rat  3288 GADASESSDDESMYQPAPVKKYTFKLKGVDEGQKDTAKSKTATTKASNQKEVESN--GKESE--S 3348

Human  3374 GLDSPQNEIAQNGNNDQSITECSIATTAEFSHDTDATEIDSLDGYDLQDEDDGLTESDSKLPIQA 3438
            ||||||||.|||||||||:|||||||||||||||||||||||||||||||||||||||||||.|.
  Rat  3349 GLDSPQNETAQNGNNDQSVTECSIATTAEFSHDTDATEIDSLDGYDLQDEDDGLTESDSKLPSQT 3413

Human  3439 MEIKKDIWNTEGILKPADRSFSQSKLEVIEEEGKVGPDEDKP-PSKSSSSEKTPDKTDQKSGAQF 3502
            ::.|||:| |||||||||||||||||||||||||||.||:|| |||||||::||:|.|.||||||
  Rat  3414 IDTKKDVW-TEGILKPADRSFSQSKLEVIEEEGKVGLDEEKPLPSKSSSSDRTPEKADPKSGAQF 3477

Human  3503 FTLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWSNNRGDDEVFDSKSREDETKPF 3567
            |||||||||||||||||||||||||||||||||||||||||||.|||||:||||.|||||:||||
  Rat  3478 FTLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVATKGLDFDPWPNNRGDNEVFDGKSREDDTKPF 3542

Human  3568 GLAVEDRSPATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFF 3632
            ||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  3543 GLAVDDRSPATTPDTTPARTPTDESTPTSEPNPFPFHEGKMFEMTRSGAIDMSKRDFVEERLQFF 3607

Human  3633 QIGEHTSEGKSGDQGEGDKSMVTATPQPQSGDTTVETNLERNVETPTVEPNPSIPTSGECQEGTS 3697
            ||||||.|||||.||||  ..||.||||:||||:|:|||||:||.|||:|||||||:|||||||:
  Rat  3608 QIGEHTPEGKSGAQGEG--GTVTDTPQPESGDTSVDTNLERDVEAPTVDPNPSIPTNGECQEGTA 3670

Human  3698 SSGSLEKSAAATNTSKVDPKLRTPIKMGISASTMTMKKEGPGEITDKIEAVMTSCQGLENETITM 3762
            .:|.||||||||||||||||.|||||||||||||||||||.|:.|||.|||:||.||||||.:..
  Rat  3671 CNGCLEKSAAATNTSKVDPKSRTPIKMGISASTMTMKKEGSGDTTDKTEAVVTSYQGLENEIVKE 3735

Human  3763 ISNTANSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVS 3827
            ||:..|||:|:||.|||||||||||||||||:|.:||||..|:||||..:|.||||||.|||| .
  Rat  3736 ISSALNSQVGIRPQEKHDFQKDNFNNNNNLDASAMQTDNTTSHIVLTGRAASTCTTEKANPVK-G 3799

Human  3828 SGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKDTFPPNHMSNTKASKMKQV 3892
            |||..|. ||...||.|         ||.||:|:|||||:|||:|||.|||||..::||.|::||
  Rat  3800 SGKSPGT-QGRSSRDSQ---------KEPIGVRRKSKLPVKATAPKDVFPPNHKPDSKAGKLRQV 3854

Human  3893 SQSEKTKALTTSSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQLPSKLPVKVRST 3957
            .|.||.|||.||||:|.|||||||||||:|:::|||||||||:||||||||||.|||||||||||
  Rat  3855 GQYEKNKALPTSSCIDSKSRIPVKNTHRENLVSVRKACATQKRGQPEKGKAKQPPSKLPVKVRST 3919

Human  3958 CVTTTTTTATTTTTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKMQ 4022
            |||.|||..:|||||||||    ||||.:||.||||||.||||||||||||||||||:||::|||
  Rat  3920 CVTVTTTNTSTTTTTTTTT----TVKVTESQRKEVCKHPIEYFKGISGETLKLVDRLTEEDRKMQ 3980

Human  4023 SELSDEEESTSRNTSLSETSRGGQPSVTTKSARDKKTEAAPLKSKSEKAGSEKRSSRRTGPQSPC 4087
            |||||.||||||:||||||||||||||||||||:|:|||.|||||..|:     .||||||||||
  Rat  3981 SELSDGEESTSRSTSLSETSRGGQPSVTTKSARNKRTEAPPLKSKRGKS-----CSRRTGPQSPC 4040

Human  4088 ERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTD 4152
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  4041 ERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTD 4105

Human  4153 ALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETSSGNLESCAQARR 4217
            ||||||||||||||||||||||||||||||||||||||||||||||||||||.||:|||.|||||
  Rat  4106 ALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETPSGSLESPAQARR 4170

Human  4218 VTGGLLDRLDDSPDQCRDSITSYLKGEAGKFEANGSHTEITPEAKTKSYFPESQNDVGKQSTKET 4282
            :|||||||||||.||.||.|||||.||||||||||:|.|:.||||.|:||||||||:||||.||.
  Rat  4171 ITGGLLDRLDDSSDQVRDPITSYLTGEAGKFEANGNHAEVIPEAKAKAYFPESQNDIGKQSIKEN 4235

Human  4283 LKPKIHGSGHVEEPASPLAAYQKSLEETSKLIIEET-KPCVPVSMKKMSRTSPADGKPRLSLHEE 4346
            ||||.||.|..|||.|||.||||||||||||:||:. ||||||.||||:|| |||||.||:|.||
  Rat  4236 LKPKTHGCGRAEEPVSPLTAYQKSLEETSKLVIEDAPKPCVPVGMKKMTRT-PADGKARLNLQEE 4299

Human  4347 EGSSGSEQKQGEGFKVKTKKEIRHVEKKSH 4376
            |||:.||.|||||:|||||||||:||||:|
  Rat  4300 EGSARSEPKQGEGYKVKTKKEIRNVEKKAH 4329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ANK3	NP_066267.2	ANK 6	234..263		28/28 (100%)
		ANK repeat	267..298	CDD:293786	30/30 (100%)
		ANK 7	267..296		28/28 (100%)
		Ank_2	272..363	CDD:289560	90/90 (100%)
		ANK	295..420	CDD:238125	123/124 (99%)
		ANK 8	300..329		28/28 (100%)
		ANK repeat	300..325	CDD:293786	24/24 (100%)
		ANK repeat	333..364	CDD:293786	30/30 (100%)
		ANK 9	333..362		28/28 (100%)
		ANK	361..486	CDD:238125	123/124 (99%)
		ANK 10	366..395		28/28 (100%)
		ANK repeat	369..397	CDD:293786	27/27 (100%)
		Ank_2	371..463	CDD:289560	90/91 (99%)
		ANK repeat	399..430	CDD:293786	29/30 (97%)
		ANK 11	399..428		27/28 (96%)
		ANK repeat	432..463	CDD:293786	30/30 (100%)
		ANK 12	432..461		28/28 (100%)
		ANK	460..585	CDD:238125	123/124 (99%)
		ANK repeat	465..496	CDD:293786	30/30 (100%)
		ANK 13	465..494		28/28 (100%)
		Ank_2	470..561	CDD:289560	90/90 (100%)
		ANK repeat	498..529	CDD:293786	30/30 (100%)
		ANK 14	498..527		28/28 (100%)
		ANK repeat	531..560	CDD:293786	28/28 (100%)
		ANK 15	531..560		28/28 (100%)
		Ank_2	536..626	CDD:289560	88/89 (99%)
		ANK	560..684	CDD:238125	121/123 (98%)
		ANK repeat	564..593	CDD:293786	27/28 (96%)
		ANK 16	564..593		27/28 (96%)
		ANK repeat	597..626	CDD:293786	28/28 (100%)
		ANK 17	597..626		28/28 (100%)
		ANK repeat	630..660	CDD:293786	28/29 (97%)
		ANK 18	630..659		27/28 (96%)
		Ank_4	631..684	CDD:290365	51/52 (98%)
		ANK	658..783	CDD:238125	123/124 (99%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44		40/42 (95%)
		Ank_4	47..94	CDD:290365	45/46 (98%)
		ANK	68..193	CDD:238125	123/124 (99%)
		ANK repeat	73..104	CDD:293786	30/30 (100%)
		ANK 1	73..102		28/28 (100%)
		Ank_2	78..164	CDD:289560	84/85 (99%)
		ANK repeat	106..137	CDD:293786	30/30 (100%)
		ANK 2	106..135		28/28 (100%)
		ANK 3	139..168		27/28 (96%)
		ANK repeat	139..164	CDD:293786	23/24 (96%)
		Ank_4	140..193	CDD:290365	51/52 (98%)
		ANK 4	172..201		28/28 (100%)
		ANK 5	203..230		25/26 (96%)
		ANK repeat	205..232	CDD:293786	24/26 (92%)
		Ank_2	206..297	CDD:289560	88/90 (98%)
		ANK	229..354	CDD:238125	123/124 (99%)
		ANK repeat	234..265	CDD:293786	30/30 (100%)
		ANK repeat	663..694	CDD:293786	29/30 (97%)
		ANK 19	663..692		27/28 (96%)
		Ank_2	669..759	CDD:289560	88/89 (99%)
		ANK repeat	696..727	CDD:293786	30/30 (100%)
		ANK 20	696..725		28/28 (100%)
		ANK repeat	729..760	CDD:293786	30/30 (100%)
		ANK 21	729..758		28/28 (100%)
		Ank_5	749..803	CDD:290568	52/53 (98%)
		ANK 22	762..791		28/28 (100%)
		ANK repeat	762..790	CDD:293786	27/27 (100%)
		ANK 23	795..825		26/29 (90%)
		ZU5	982..1086	CDD:128514	103/103 (100%)
UPA domain. /evidence=ECO:0000250	1273..1407		129/133 (97%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1519..1540		17/20 (85%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1968..1987		15/18 (83%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2107..2159		50/51 (98%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2176..2245		57/68 (84%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2299..2322		20/22 (91%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2383..2433		44/49 (90%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2474..2508		32/33 (97%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2588..2751		128/164 (78%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2795..2824		16/28 (57%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3036..3067		27/30 (90%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3131..3272		116/140 (83%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3298..3516		180/220 (82%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3538..3607		63/68 (93%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3635..3718		64/82 (78%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3868..3897		17/28 (61%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	4019..4090		55/70 (79%)
Death_ank3	4088..4171	CDD:176781	82/82 (100%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	4251..4298		33/46 (72%)
Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	4323..4377		42/54 (78%)
Ank3	XP_038954762.1	PHA03095	60..>327	CDD:222980	262/266 (98%)
		ANK repeat	73..104	CDD:293786	30/30 (100%)
		ANK repeat	106..137	CDD:293786	30/30 (100%)
		ANK repeat	139..164	CDD:293786	23/24 (96%)
		Ank_2	195..>429	CDD:423045	230/233 (99%)
		ANK repeat	205..232	CDD:293786	24/26 (92%)
		ANK repeat	234..265	CDD:293786	30/30 (100%)
		ANK repeat	267..298	CDD:293786	30/30 (100%)
		ANK repeat	300..325	CDD:293786	24/24 (100%)
		ANK repeat	333..364	CDD:293786	30/30 (100%)
		PHA03095	369..>657	CDD:222980	284/287 (99%)
		ANK repeat	369..397	CDD:293786	27/27 (100%)
		ANK repeat	399..430	CDD:293786	29/30 (97%)
		ANK repeat	432..463	CDD:293786	30/30 (100%)
		ANK repeat	465..496	CDD:293786	30/30 (100%)
		ANK repeat	498..529	CDD:293786	30/30 (100%)
		ANK repeat	531..560	CDD:293786	28/28 (100%)
		Ank_2	551..>788	CDD:423045	233/236 (99%)
		ANK repeat	564..593	CDD:293786	27/28 (96%)
		ANK repeat	597..626	CDD:293786	28/28 (100%)
		ANK repeat	630..661	CDD:293786	29/30 (97%)
		ANK repeat	663..694	CDD:293786	29/30 (97%)
		ANK repeat	696..727	CDD:293786	30/30 (100%)
		ANK repeat	729..760	CDD:293786	30/30 (100%)
		ANK repeat	762..790	CDD:293786	27/27 (100%)
		Ank_4	763..815	CDD:372654	50/51 (98%)
		ZU5	982..1086	CDD:128514	103/103 (100%)
		UPA_2	1308..1437	CDD:375346	125/128 (98%)
		Herpes_BLLF1	<1477..1879	CDD:282904	354/403 (88%)
		PTZ00449	<2044..2316	CDD:185628	250/271 (92%)
		DUF2890	3229..>3350	CDD:314108	94/124 (76%)
		Death_ank3	4041..4124	CDD:176781	82/82 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83678099
Domainoid	1	1.000	448	1.000	Domainoid score	I9062
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56908
Inparanoid	1	1.050	4290	1.000	Inparanoid score	I177
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	1	1.000	-	-		FOG0000917
OrthoInspector	1	1.000	-	-		oto133467
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1361
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	14.300