Protein Alignment GPX1 and Gtpx

DIOPT Version :10

• Sequence 1: NP_000572.2
• Gene: GPX1 / 2876
• HGNCID: 4553
• Length: 203
• Species: Homo sapiens
• Sequence 2: NP_728869.1
• Gene: Gtpx / 38413
• FlyBaseID: FBgn0035438
• Length: 238
• Species: Drosophila melanogaster
• Alignment Length: 205
• Identity: 72/205 - (35%)
• Similarity: 104/205 - (50%)
• Gaps: 36/205 - (17%)

Human     3 AARLAAAAAA----------AQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYT 57
            ||:.:.|||.          |.|:|.|:.:...|.: |||...:|||:|:.|:||..|.|..:|.
  Fly    59 AAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGND-VSLEKYKGKVVLVVNIASKCGLTKNNYE 122

Human    58 QMNELQRRLGPRGLVVLGFPCNQFGHQ-ENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAG 121
            ::.:|:.:.|.||||:|.|||||||.| ..|..|.::..|:..:...|     .:|.|.:|||..
  Fly   123 KLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIG-----EVFAKVDVNGDN 182

Human   122 AHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTI 186
            |.||:.:|:           |..|.        ...:.:.|||.||||..:|||:.||:.....:
  Fly   183 AAPLYKYLK-----------AKQTG--------TLGSGIKWNFTKFLVNKEGVPINRYAPTTDPM 228

Human   187 DIEPDIEALL 196
            ||..|||.||
  Fly   229 DIAKDIEKLL 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPX1	NP_000572.2	GSH_Peroxidase	15..192	CDD:238207	61/177 (34%)
Gtpx	NP_728869.1	GSH_Peroxidase	81..234	CDD:238207	61/177 (34%)