Protein Alignment GPX1 and Gpxl

DIOPT Version :10

• Sequence 1: NP_000572.2
• Gene: GPX1 / 2876
• HGNCID: 4553
• Length: 203
• Species: Homo sapiens
• Sequence 2: NP_611393.2
• Gene: Gpxl / 37194
• FlyBaseID: FBgn0034415
• Length: 193
• Species: Drosophila melanogaster
• Alignment Length: 185
• Identity: 62/185 - (33%)
• Similarity: 88/185 - (47%)
• Gaps: 31/185 - (16%)

Human    15 SVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCN 79
            :::|.:.|. ..|.||.|.:..|.||||.|:||. |.|:..|..:..|......:||.:|.||||
  Fly    39 TIHALTVRD-TFGNPVQLDTFAGHVLLIVNIASKCGLTLSQYNGLRYLLEEYEDQGLRILNFPCN 102

Human    80 QFGHQ-ENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATAL 143
            |||.| ..:..:|:|:.|:  |.|....   .||.|.:|.||.|.||:
  Fly   103 QFGGQMPESDGQEMLDHLR--REGANIG---HLFAKIDVKGAQADPLY----------------- 145

Human   144 MTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQ 198
                ||:|..   ::|:.|||.||||...|...:||....:.:.:..|||.||.:
  Fly   146 ----KLLTRH---QHDIEWNFVKFLVDRKGNIHKRYGAELEPVALTDDIELLLGR 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPX1	NP_000572.2	GSH_Peroxidase	15..192	CDD:238207	57/177 (32%)
Gpxl	NP_611393.2	GSH_Peroxidase	39..187	CDD:238207	57/177 (32%)