Protein Alignment Rnf145 and rnf145b

DIOPT Version :9

• Sequence 1: NP_001099248.1
• Gene: Rnf145 / 287212
• RGDID: 1309561
• Length: 664
• Species: Rattus norvegicus
• Sequence 2: NP_956057.1
• Gene: rnf145b / 327056
• ZFINID: ZDB-GENE-030131-5264
• Length: 685
• Species: Danio rerio
• Alignment Length: 664
• Identity: 536/664 - (80%)
• Similarity: 587/664 - (88%)
• Gaps: 11/664 - (1%)

  Rat     1 MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYIL 65
            ||.|.:||:||||.||:||||||:||||||||||||:||||||:|||:|||||:||.:|||||||
Zfish     1 MAMKARLESVLNVGLRIPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPVFQYKYIALYLHYVGYIL 65

  Rat    66 SVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQ 130
            |:||||||||||||||||.||||||:||||:||||||.||:|.||||:|||||||||||||||||
Zfish    66 SLVLLTLPRQHLVQLYLYVLTALLLFAGHQLSRDYVRGELDSGYEGPLYLEPLSMNRFTTALIGQ 130

  Rat   131 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPY 195
            :||||||||||:|:||||||||:|||:||||||||||||.||:|||||||||||||:.|||||||
Zfish   131 VVVCTLCSCVMQTRQIWLFSAHLLPLVARLCLVPLETIVFINRFAMIFTGLEVLYFIASNLLVPY 195

  Rat   196 NLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLL 260
            ||||:||||||||||||||||||||||||||:|||||.|||||||||||:||||||||.||||||
Zfish   196 NLAKTAYRELVQVVEVYGLLALGMSLWNQLVLPVLFMCFWLVLFALQIYTYFSTRDQPPSRERLL 260

  Rat   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 325
            ||||||||||||||||||||||||||||||||||||||||||||||||.||:||||||:||||||
Zfish   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDNAMHRGMTEGITLLILA 325

  Rat   326 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   326 VQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390

  Rat   391 VFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVN 455
            ||||||||||||||.|||||||||||||||||||||||.||||||||||||.||||||:||||||
Zfish   391 VFPAYMAYMICQFFRMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEEFRKAPVENMDEVIYYVN 455

  Rat   456 GTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 520
            |||||||||||:||||||||||:|||||||||.||.:||||||||||||||:|||||||||:||:
Zfish   456 GTYRLLEFLVAVCVVAYGVSETLFGEWTVMGSTIILVHSYYNVWLRAQLGWQSFLLRRDAVHKIQ 520

  Rat   521 SLPIATKEQLERHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQ-- 583
            |:|.|:..||::|||||:||:|||||||||||||||||.|||||||||:||||||..||:..|
Zfish   521 SMPTASTLQLQQHNDICSICFQDMKSAVITPCSHFFHAACLKKWLYVQETCPLCHGQLKSQLQPT 585

  Rat   584 -LPGLGTEPAPQPPVAGAEQN--IVLQEGPEPP-DHETPPGPGAQEGSGDNSEYINRSSASREGD 644
             .||..|:..|     .|.||  .|.||..:|. :..|..|..|:|......:.:.........:
Zfish   586 SSPGTPTQGTP-----AANQNPREVEQEQRQPQVELNTEEGIRAEEMKTSAEQKLGMDLLPGSLN 645

  Rat   645 ADPGDGPQIAEGEA 658
            ..|.:...:|||.|
Zfish   646 TQPKECDLVAEGSA 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf145	NP_001099248.1	TRC8_N	8..506	CDD:404574	452/497 (91%)
		HRD1	<520..643	CDD:227568	62/128 (48%)
		RING-H2_RNF145	533..575	CDD:319598	37/41 (90%)
rnf145b	NP_956057.1	TRC8_N	8..506	CDD:290425	452/497 (91%)
		zf-RING_2	535..575	CDD:290367	35/39 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..685		21/83 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194903078
Domainoid	1	1.000	915	1.000	Domainoid score	I492
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1067	1.000	Inparanoid score	I1886
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D119734at7742
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	1	1.000	-	-		otm32409
orthoMCL	1	0.900	-	-		OOG6_109881
Panther	1	1.100	-	-	O	PTHR22763
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770