Protein Alignment Rnf145 and hrd1

DIOPT Version :9

• Sequence 1: NP_001099248.1
• Gene: Rnf145 / 287212
• RGDID: 1309561
• Length: 664
• Species: Rattus norvegicus
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 514
• Identity: 103/514 - (20%)
• Similarity: 179/514 - (34%)
• Gaps: 177/514 - (34%)

  Rat   229 VLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVF-TVSFVALGV- 291
            :|:::..||||.|.:               ||.|:.:      :..||...::. :...:.:|:
pombe     4 ILYVLASLVLFGLSV---------------LLSLYSS------ANVYSATVMISQSPVHITIGLN 47

  Rat   292 LTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQS 356
            :.||.|:     |..|  |:.       |||..::||  .||::::..|.:::
pombe    48 VCLCLFF-----AIAN--ALK-------TLLFGSLQT--FELELLYEQFWITL------------ 84

  Rat   357 MLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQF-------------FHM-- 406
                 ..|:||:...|:......|..:|..:|..||     :.||.|             ||:
pombe    85 -----TEIMLAITVFREAISISFFMLLSTLMFARVF-----HSICSFRTERLQIQLTDQRFHIFS 139

  Rat   407 ----DFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLV-- 465
                .:::|.|:.:|:           ||:.|..|....:...    :::....:..||...:
pombe   140 RLTCAYFVLSILDASL-----------IYLCFTSEHLGDKSTR----MLFVCEFSVLLLNLTIEA 189

  Rat   466 -ALCVVAYGVS--ETIFGEWT--------------VMGSMIIFIHS-----------------YY 496
             .||:..|...  :.::.|.:              ::...::|::.                 :|
pombe   190 SKLCIYLYEARHLDQVWDEKSTYLFRLEVCRDGLRLLAYSLLFMYQFPYVSVPIYSIRQMYTCFY 254

  Rat   497 NVWLRAQLGWKSFLLRRDAVNKIKSL-PIATKEQLERHNDICAICYQDM---------------- 544
            :::.|.    :.....|.|...:.:: |.||:|||...:..|.||.::|
pombe   255 SLFRRI----REHARFRQATRDMNAMYPTATEEQLTNSDRTCTICREEMFHPDHPPENTDEMEPL 315

  Rat   545 -KSAVIT----PCSHFFHAGCLKKWLYVQDTCPLC-HCHLKNSSQLPGLGTEP----------AP 593
             :...:|    ||.|..|..||:.||..|.|||:| ...:.|.|...|:...|          .|
pombe   316 PRGLDMTPKRLPCGHILHFHCLRNWLERQQTCPICRRSVIGNQSSPTGIPASPNVRATQIATQVP 380

  Rat   594 QP---PVAGAEQNIVLQEGPEPPDHETPPGPGAQEGSG------DNSEYINRSSASREG 643
            .|   |...|...|........|...|..|......||      |.|..|.|..|.|:|
pombe   381 NPQNTPTTTAVPGITNSSNQGDPQASTFNGVPNANSSGFAAHTQDLSSVIPRRIALRDG 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf145	NP_001099248.1	TRC8_N	8..506	CDD:404574	56/333 (17%)
		HRD1	<520..643	CDD:227568	44/164 (27%)
		RING-H2_RNF145	533..575	CDD:319598	18/63 (29%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	103/514 (20%)
		zf-RING_2	291..351	CDD:290367	17/59 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770