Protein Alignment GRK6 and Grk6

DIOPT Version :10

• Sequence 1: NP_002073.2
• Gene: GRK6 / 2870
• HGNCID: 4545
• Length: 589
• Species: Homo sapiens
• Sequence 2: NP_113845.2
• Gene: Grk6 / 59076
• RGDID: 61986
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 567/589 - (96%)
• Similarity: 576/589 - (97%)
• Gaps: 0/589 - (0%)

Human     1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRL 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRL 65

Human    66 LFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCT 130
            ||||||||||||:||.||||||||||||||:|||||||:|.||||||||||||||||||||:||.
  Rat    66 LFREFCATRPELTRCTAFLDGVAEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCA 130

Human   131 QRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKG 195
            ||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||
  Rat   131 QRLEQGPCKDLFQELTRLTHEYLSMAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKG 195

Human   196 GFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALC 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 GFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALC 260

Human   261 LVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 LVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHI 325

Human   326 RISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKK 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 RISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKK 390

Human   391 KIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKR 455
            ||||||||||||||.|||::||||||||||||||.||||||||||||.|||||||||||||||||
  Rat   391 KIKREEVERLVKEVAEEYTDRFSPQARSLCSQLLNKDPAERLGCRGGGAREVKEHPLFKKLNFKR 455

Human   456 LGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETEC 520
            ||||||||||||||||||||||||||||||||||:|||||||||||||||||.||||||||||||
  Rat   456 LGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETEC 520

Human   521 FQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPT 585
            |||||||||||||||||||||||.|||||||||||||||||||.||||.:||||||||||.||||
  Rat   521 FQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQRIAVGTAATVKKSSPPASSPQAEAPT 585

Human   586 SSWR 589
            ..||
  Rat   586 GGWR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRK6	NP_002073.2	N-terminal	1..185		175/183 (96%)
		RGS	35..179	CDD:470619	135/143 (94%)
		STKc_GRK6	185..469	CDD:270779	278/283 (98%)
Grk6	NP_113845.2	N-terminal	1..185		175/183 (96%)
		RGS	35..179	CDD:470619	135/143 (94%)
		STKc_GRK6	185..469	CDD:270779	278/283 (98%)