Protein Alignment GRK6 and Grk6

DIOPT Version :10

• Sequence 1: NP_002073.2
• Gene: GRK6 / 2870
• HGNCID: 4545
• Length: 589
• Species: Homo sapiens
• Sequence 2: NP_001033107.1
• Gene: Grk6 / 26385
• MGIID: 1347078
• Length: 589
• Species: Mus musculus
• Alignment Length: 589
• Identity: 565/589 - (95%)
• Similarity: 574/589 - (97%)
• Gaps: 0/589 - (0%)

Human     1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRL 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRL 65

Human    66 LFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCT 130
            ||||||||||||:||.||||||:|||||||:|||||||:|.||||||||||||||||||||:||.
Mouse    66 LFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCA 130

Human   131 QRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKG 195
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||
Mouse   131 QRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKG 195

Human   196 GFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALC 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 GFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALC 260

Human   261 LVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 LVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHI 325

Human   326 RISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKK 390
            ||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||
Mouse   326 RISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKK 390

Human   391 KIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKR 455
            ||||||||||||||.|||::|||.||||||||||.||||||||||||.|||||||||||||||||
Mouse   391 KIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKR 455

Human   456 LGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETEC 520
            ||||||||||||||||||||||||||||||||||:|||||||||||||||||.||||||||||||
Mouse   456 LGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETEC 520

Human   521 FQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPT 585
            |||||||||||||||||||||||.|||||||||||||||||||.||||.|||||||||||.||||
Mouse   521 FQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQRIAVGTAATVRKSSPPASSPQAEAPT 585

Human   586 SSWR 589
            ..||
Mouse   586 GGWR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GRK6	NP_002073.2	N-terminal	1..185		174/183 (95%)
		RGS	35..179	CDD:470619	134/143 (94%)
		STKc_GRK6	185..469	CDD:270779	276/283 (98%)
Grk6	NP_001033107.1	N-terminal	1..185		174/183 (95%)
		RGS	35..179	CDD:470619	134/143 (94%)
		STKc_GRK6	185..469	CDD:270779	276/283 (98%)