DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ANK2 and Ank2

DIOPT Version :9

Sequence 1:	NP_001373103.1	Gene:	ANK2 / 287	HGNCID:	493	Length:	4183	Species:	Homo sapiens
Sequence 2:	XP_038959927.1	Gene:	Ank2 / 362036	RGDID:	620156	Length:	4173	Species:	Rattus norvegicus

Alignment Length:	4161	Identity:	3500/4161 - (84%)
Similarity:	3694/4161 - (88%)	Gaps:	54/4161 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    46 SDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 110
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    44 SDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 108

Human   111 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQST 175
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   109 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQST 173

Human   176 ATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSK 240
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   174 ATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSK 238

Human   241 MMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 305
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   239 MMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 303

Human   306 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ 370
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   304 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQ 368

Human   371 HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV 435
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   369 HKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLV 433

Human   436 KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 500
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   434 KYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 498

Human   501 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASV 565
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   499 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASV 563

Human   566 LLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVAL 630
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   564 LLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVAL 628

Human   631 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMV 695
            |||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||
  Rat   629 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMV 693

Human   696 TLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKM 760
            ||||:||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
  Rat   694 TLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKM 758

Human   761 VNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYIS 825
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   759 VNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYIS 823

Human   826 VVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEALKQFGDHFIDGEALSDSGDDTMT 890
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
  Rat   824 VVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEALKQFGDHFIDGEALSDSGDDTVT 888

Human   891 GDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSD----SLRSFSSDRSHTLSHASYL 951
            ||||||||||||||||||||||||||||||||||||||||||    |||||||||||||||||||
  Rat   889 GDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSTIPSLRSFSSDRSHTLSHASYL 953

Human   952 RDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGRASPCLERDNS--- 1013
            ||||::||:|||||||||.||||||||||||||||||||||||||||||||||||||:||||
  Rat   954 RDSAMIDDTVVIPSHQVSALAKEAERNSYRLSWGTENLDNVALSSSPIHSGRASPCLDRDNSRRC 1018

Human  1014 -----SFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGL 1073
                 .|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1019 LPKRPCFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGL 1083

Human  1074 ASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKE 1138
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1084 ASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKE 1148

Human  1139 RELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSR 1203
            |||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
  Rat  1149 RELVVLRSENGDSWKEHFCEYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSR 1213

Human  1204 IKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVT 1268
            ||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||
  Rat  1214 IKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVT 1278

Human  1269 LEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVN 1333
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1279 LEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVN 1343

Human  1334 ECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTD 1398
            |||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||
  Rat  1344 ECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTD 1408

Human  1399 DKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVK 1463
            |||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat  1409 DKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVK 1473

Human  1464 VRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNDETES 1528
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||.|||||||||||
  Rat  1474 VRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEICMTSEKNDETES 1538

Human  1529 TETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELVKAAEEEPG 1593
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||.|||||
  Rat  1539 TETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELAKAGEEEPG 1603

Human  1594 EPFEIVERVKEDLEKVNEILRSGTCTRDESSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEI 1658
            |||||||||||||||||.||||||..|||.||:||:|||.| |||||||||||||||:|.||:||
  Rat  1604 EPFEIVERVKEDLEKVNAILRSGTYMRDEGSVRSSQSEREL-EEEWVIVSDEEIEEAKQHAPVEI 1667

Human  1659 TEYPCVEVRIDKEIKGKVEKDSTGLVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSE 1723
            .|:||||||:|:|.|.||||||||||||||||||:.....:::.||..:|:|:..:|.|:.:|||
  Rat  1668 AEHPCVEVRVDRETKTKVEKDSTGLVNYLTDDLNSYTGTHEKKPQTAPEKSGETSQASAIVKSSE 1732

Human  1724 -KEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGED 1787
             .:||..|.:|.||.|||.||||.||||||||||||||||||..|.|.||.||||||||||:.||
  Rat  1733 SNKGKTSPAEEKQSAQKQVKPSLVIKKPVRRKLKEKQKQKEESPQGSEEKTELKKGSSEESVDED 1797

Human  1788 PGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRP 1852
            .|||||||||.|||||||||||||||||||||||||||||||||||||:|||||||||||||.|.
  Rat  1798 RGLAPEPLPTAKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPVRVKGKEDVPKKTTPRT 1862

Human  1853 HPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPAS 1917
            ||..|||.||      |||.|.||||:|:||||||||.|||||||.|||||||||||.|||||.
  Rat  1863 HPVVSPSSKS------SPSSKMERHSSLTSSAKTERHSPVSPSSKNEKHSPVSPSAKAERHSPV- 1920

Human  1918 SSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEK 1982
            .|.|.|||||.|||||.||||||||.|||||.||||||||||||||..|||||||||||||:|||
  Rat  1921 FSGKPEKHSPGSPSTKNERHSPVSSIKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPGKTEK 1985

Human  1983 RLPVSPSGRT-DKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQS 2046
            |.|.:||.|| :|..|.|..||.|||||||| ||||||||:||||||||||||||||||||||||
  Rat  1986 RSPGAPSIRTPEKQAPGSATGKHEKHLPVSP-GKTEKQPPISPTSKTERIEETMSVRELMKAFQS 2049

Human  2047 GQDPSKHKTGLFEHKSAKQKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAES 2111
            |||||||||||||||||||||.|:|.|.|||||||..:||||.|:.||||.|||||..|||..||
  Rat  2050 GQDPSKHKTGLFEHKSAKQKQSQDKSKSRVEKEKGHSVTQRETQRIENQTAKRGQRFQVTGAMES 2114

Human  2112 KRGVRVS-SIGVKKEDAAGGK-EKVLSHKIPEPVQSV-------PEEESHRESEVPKEKMADEQG 2167
            :|....: ::|::.||....: |:....|.||.|..|       ..|||||.:|..:||..|||.
  Rat  2115 RRFRSTTITVGLRTEDPVRERFERTPVIKTPEAVPPVAAAVAAAAAEESHRGAETLQEKTVDEQE 2179

Human  2168 DMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKD 2232
            |||||||||||||||||:|||||||||||||||||:|.|||||:|||||:|||||||||||||||
  Rat  2180 DMDLQISPDRKTSTDFSDVIKQELEDNDKYQQFRLTENTEKAQIHLDQVITSPFNTTFPLDYMKD 2244

Human  2233 EFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFS 2297
            |||||||||||||.|||||||.|.:||||||||||||||||||||||||||||||||||||||||
  Rat  2245 EFLPALSLQSGALGGSSESLKQEVIAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFS 2309

Human  2298 PKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEATLGS 2362
            ||||:||.||.||:.|.||.|:|.||||.|.|.||...||::||.|..||    |...||.|...
  Rat  2310 PKKSKEQIGEAKETIKVETPTDIHSEKELPITNDIADSSEKQGAGVPGDS----EHVLKEVTQVP 2370

Human  2363 PKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETK 2427
            |||...| |:||.||.||:||.||...||||.:|.:.|....|||.|||..||.|||.|||:.||
  Rat  2371 PKDVCSK-QEDCPGSHSVSLANETCQALTEEGSCRDSQLPLVSSACKTQAVSETQESLATSEVTK 2434

Human  2428 ALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDSLAVSHKDSLEASPVLED 2492
            |.|..:|:|||..|||.||||||||||||||.|.:|||||||.:||:||||||||||||||||||
  Rat  2435 AFPPSDATVKTVEGTEPKPQGVIRSPQGLELPLHNRDSEVLSPMADESLAVSHKDSLEASPVLED 2499

Human  2493 NSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLL 2557
            |||||||||||||||||||||||||||||||||||||.|||||||||:|||:|:.||||:|||||
  Rat  2500 NSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLL 2564

Human  2558 RDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSE 2622
            |||||||||||||||||||||||||||||||||||||||||||.:|.||||||||||||||||||
  Rat  2565 RDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKPSDSSTPKPAVIHECAEEDDSE 2629

Human  2623 NGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHT 2687
            |||||||||||||||||||||.|||||||||||||||:||:|:|||||||||||||.:|||.|..
  Rat  2630 NGEKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYKREPRQDESSSSSDPDADCSAEVDEQKQM 2694

Human  2688 GSGEDESGVPVLVTSESRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSP 2752
            ||.|.||.|||||||||||.||||||||||.||.||||||||.|||||||||||||||:||||||
  Rat  2695 GSTEGESDVPVLVTSESRKASSSSESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNSSP 2759

Human  2753 EEVQFQPVVSKQYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPK 2817
            ||.||||:|.|||||||||:.:|:||..||:||.:||||||....|.:..|.|:..|||:|.|.:
  Rat  2760 EEAQFQPIVPKQYTFKMNEEVKEDPGNPEEDKDCKSHLAEDSQTHSADGADGSHADLNRETPQLE 2824

Human  2818 ICDGHGCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRAESP 2882
            .||||||:|:|||:||.|||.|:|||...|||:...|..:|||||.||..|.|..|.|.||.||.
  Rat  2825 ACDGHGCKAVSPSNSATPVSLGVQSPECHDVDKPLAIDNDSLALQDTHGSDLEEREFDPSRVEST 2889

Human  2883 QADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPSQDSSITTQ 2947
            ||..||| .||.||..||.|.|..|..::||:.||..|.|||.||...|::.:|||:|::|.||.
  Rat  2890 QASLPSE-HSSLSSSSHCAVPEENESAKEISSPSSPVKVEVTVTDPVLESMSEDCPTQEASTTTH 2953

Human  2948 TDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESKTQTDANHTTSFHSSEVYSVTIT 3012
            |:||:||.||||:||.||...||||||||||.|.||||.|.|..|||..|.|..||.|||||.|.
  Rat  2954 TERFAMDGPVSDIAETDENSHPQITSPYENVASSSFFSGEPSNFQTDTCHPTVVHSPEVYSVIIR 3018

Human  3013 SPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQESTLWEMQSDSVSSSFEPTMSATTTVVGEQI 3077
            |..|||::.||||.|...:.||.||.|:..|.:|:|.||.||||....|..||......|.|||:
  Rat  3019 SSPEDVIMTSSSSRTDSGEASNCEGHDLDTECEQKSALWPMQSDEPPLSVAPTTPNAPVVTGEQV 3083

Human  3078 SKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPT 3142
            |||||||||||:||||||||||.||||||||||||||||||||||||||||||||||||||||||
  Rat  3084 SKVIITKTDVDADSWSEIREDDAAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPT 3148

Human  3143 SEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESFHFFQIGQESREETLSEDVKEGATGADPLPLE 3207
            |||||||||||||||||||||||||||||||||.|||||||:|.|||:|||:|||||||:|...|
  Rat  3149 SEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESLHFFQIGQDSNEETISEDLKEGATGAEPPQTE 3213

Human  3208 TSAESLALSESKETVDDEADLLPDDVSEEVEEIPASDAQLNSQMGISASTETPTKEAVSVGTKDL 3272
            |::|||.||..||.:|||.:|:|||||||:|::|||||.|:|::.||||||||||||||...::.
  Rat  3214 TTSESLELSGPKEAMDDEGELVPDDVSEEIEDLPASDADLDSKVVISASTETPTKEAVSTVAEEP 3278

Human  3273 PTVQTGDIPPLSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPTA 3337
            .|:|..|  .||.|||.|||...||.  .||||||:||||||||.|:||||||||||||||||||
  Rat  3279 ATMQWSD--SLSTVKQTSCPTFPEPV--GQLDFSTVTRSVYSDRDDESPDSSPEEQKSVIEIPTA 3339

Human  3338 PMENVPFTESKSKIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPVKVPLQ 3402
            ||||||..|.|.:||:||:|||..||||||.||:.|:||.|.:|.|::.|.||||||:|:|.|.|
  Rat  3340 PMENVPSAEIKPQIPIRTLPTSVSAPPSAEDESAFSDDFPSGLDGESEEDGAKPKSKIPIKAPPQ 3404

Human  3403 RVEQQLSDLDTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTRSYTETETESRER 3467
            |.|...|..|.|:||:..|||||:.|..||.||||||||||||:|||||||.|||.|||||||||
  Rat  3405 RTEWHPSHPDISLQKSGVPQGQDVLSRGPDGRSKSESDASSLDAKTKCPVKARSYIETETESRER 3469

Human  3468 AEELELESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTKESKEHFFDLYRNSIEFFEEISDEA 3532
            ||..|.|||||||:||:..||||||||||:||.|.|||||:||:|||||||||||||||||||||
  Rat  3470 AEGFESESEEGATKPKLFASRLPVKSRSTSSSSRTGTSPTRESREHFFDLYRNSIEFFEEISDEA 3534

Human  3533 SKLVDRLTQSEREQEIVSDDESSSALEVSVIENLPPVETEHSVPEDIFDTRPIWDESIETLIERI 3597
            |||||||||||||||..||||||||||||||||||||:||||.|||||||||||||||||:||||
  Rat  3535 SKLVDRLTQSEREQEPPSDDESSSALEVSVIENLPPVDTEHSAPEDIFDTRPIWDESIETMIERI 3599

Human  3598 PDENGHDHAEDPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHA 3662
            |||||||.||||||||||:||||||||||||||||||||||||||||||||||||||||||||||
  Rat  3600 PDENGHDRAEDPQDEQERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHA 3664

Human  3663 LLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFS 3727
            ||||||||||||||||.|:||||||||||||||:||||||||||:..:|||:|||||||||||||
  Rat  3665 LLKYWLERDGKHATDTVLIECLTKINRMDIVHLLETNTEPLQERMGRTYAEMEQTITLDHSEGFS 3729

Human  3728 VLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTH 3792
            ||.||||..  |:|:||..|||||:.||||:|||||||||||||||.:|||||||.|.||.||.|
  Rat  3730 VLPEELCAV--KEKKEQEASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAAALSPQMH 3792

Human  3793 KEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKL 3857
            :|.|||||||||||         ||||:|||||.|..:||||.::|.|..||||::|||.||.|.
  Rat  3793 QESVQQDFSGKMQD---------QQEYYVTTPGAEVEDTQKATVIPDSLCKTPEDISTPPEEAKP 3848

Human  3858 YLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKELTEE 3922
            .||||.:.|. .|||:|||||.||.:|||||||||||||||.|:||:..|:||.||||:||||||
  Rat  3849 CLQTPVAIEH-ASPIVQEPEEASEPKEESSPRKTSLVIVESTDDQPQVFEKLDGDAAFQKELTEE 3912

Human  3923 LGELEASSDEEAMVTTRVVRRRVIIQGDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIRRYVS 3987
            |||||||||||||||||||||||||||||||:|||||||||||:||:||||||||||||||||||
  Rat  3913 LGELEASSDEEAMVTTRVVRRRVIIQGDDMPDIPPETVTEEEYVDENGHTVVKKVTRKIIRRYVS 3977

Human  3988 SEGTEKEEIMVQGMPQEPVNIEEGDGYSKVIKRVVLKSDTEQSEVTLCEPSILSSTSQFQAEPVE 4052
            |:|||||||.:|||||||||||:||.||||||||||||||:.|||||.||||:|.||||||||||
  Rat  3978 SDGTEKEEITMQGMPQEPVNIEDGDSYSKVIKRVVLKSDTQLSEVTLSEPSIVSGTSQFQAEPVE 4042

Human  4053 GRRVSKVVKTTVVLGERMEKHLGDSSLATDLPSAKDDFEEALSYTGSHMKVHLPSLVENEILKED 4117
            |||||||||||:|.||||||.||||||||||||||:||||||.||||||||||||||||||||||
  Rat  4043 GRRVSKVVKTTMVHGERMEKSLGDSSLATDLPSAKEDFEEALGYTGSHMKVHLPSLVENEILKED 4107

Human  4118 GSIIKRTTMSKAITQKRAVVKDQHGKRIDLEHLEDVPEALDQDDLQRDLQQLLRHFCKEDLKQEA 4182
            ||||||||||||.||:|||||||.||.|:||||||||.|||||||||||||||||||||:.||||
  Rat  4108 GSIIKRTTMSKARTQRRAVVKDQQGKCINLEHLEDVPGALDQDDLQRDLQQLLRHFCKENTKQEA 4172

Human  4183 K 4183
            |
  Rat  4173 K 4173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ANK2	NP_001373103.1	Ank_2	35..>311	CDD:423045	264/264 (100%)
		ANK repeat	80..111	CDD:293786	30/30 (100%)
		ANK repeat	113..144	CDD:293786	30/30 (100%)
		ANK repeat	146..171	CDD:293786	24/24 (100%)
		Ank_2	202..>444	CDD:423045	241/241 (100%)
		ANK repeat	212..247	CDD:293786	34/34 (100%)
		ANK repeat	249..280	CDD:293786	30/30 (100%)
		ANK repeat	282..313	CDD:293786	30/30 (100%)
		ANK repeat	315..345	CDD:293786	29/29 (100%)
		ANK repeat	348..379	CDD:293786	30/30 (100%)
		ANK repeat	381..411	CDD:293786	29/29 (100%)
		ANK repeat	414..445	CDD:293786	30/30 (100%)
		PHA03095	421..>706	CDD:222980	282/284 (99%)
		ANK repeat	447..478	CDD:293786	30/30 (100%)
		ANK repeat	480..511	CDD:293786	30/30 (100%)
		ANK repeat	513..542	CDD:293786	28/28 (100%)
		ANK repeat	546..571	CDD:293786	24/24 (100%)
		Ank_2	578..>802	CDD:423045	220/223 (99%)
		ANK repeat	579..604	CDD:293786	24/24 (100%)
		ANK repeat	612..643	CDD:293786	30/30 (100%)
		ANK repeat	645..676	CDD:293786	29/30 (97%)
		ANK repeat	678..707	CDD:293786	27/28 (96%)
		ANK repeat	711..742	CDD:293786	30/30 (100%)
		ANK repeat	744..775	CDD:293786	30/30 (100%)
		ANK repeat	777..806	CDD:293786	28/28 (100%)
		Ank_4	778..830	CDD:372654	51/51 (100%)
		ZU5	1013..1150	CDD:128514	135/144 (94%)
		UPA_2	1371..1500	CDD:375346	127/128 (99%)
		PspC_subgroup_1	1549..>1922	CDD:411407	289/373 (77%)
		PTZ00449	<1717..2161	CDD:185628	330/454 (73%)
		Streccoc_I_II	<1843..>2027	CDD:411384	140/184 (76%)
		Spc7_N	<2493..>2634	CDD:373822	131/140 (94%)
		rad2	<3031..>3565	CDD:273166	395/533 (74%)
		PRK14949	<3196..>3442	CDD:237863	157/245 (64%)
		Death_ank2	3614..3697	CDD:260066	79/82 (96%)
		NESP55	<3770..>3884	CDD:115071	70/113 (62%)
Ank2	XP_038959927.1	Ank_2	52..>309	CDD:423045	256/256 (100%)
		ANK repeat	78..109	CDD:293786	30/30 (100%)
		ANK repeat	111..142	CDD:293786	30/30 (100%)
		ANK repeat	144..169	CDD:293786	24/24 (100%)
		Ank_2	200..>442	CDD:423045	241/241 (100%)
		ANK repeat	210..245	CDD:293786	34/34 (100%)
		ANK repeat	247..278	CDD:293786	30/30 (100%)
		ANK repeat	280..311	CDD:293786	30/30 (100%)
		ANK repeat	313..343	CDD:293786	29/29 (100%)
		ANK repeat	346..377	CDD:293786	30/30 (100%)
		ANK repeat	379..409	CDD:293786	29/29 (100%)
		ANK repeat	412..443	CDD:293786	30/30 (100%)
		PHA03095	419..>704	CDD:222980	282/284 (99%)
		ANK repeat	445..476	CDD:293786	30/30 (100%)
		ANK repeat	478..509	CDD:293786	30/30 (100%)
		ANK repeat	511..540	CDD:293786	28/28 (100%)
		ANK repeat	544..569	CDD:293786	24/24 (100%)
		Ank_2	576..>800	CDD:423045	220/223 (99%)
		ANK repeat	577..602	CDD:293786	24/24 (100%)
		ANK repeat	610..641	CDD:293786	30/30 (100%)
		ANK repeat	643..674	CDD:293786	29/30 (97%)
		ANK repeat	676..705	CDD:293786	27/28 (96%)
		ANK repeat	709..740	CDD:293786	30/30 (100%)
		ANK repeat	742..773	CDD:293786	30/30 (100%)
		ANK repeat	775..804	CDD:293786	28/28 (100%)
		Ank_4	776..828	CDD:372654	51/51 (100%)
		ZU5	1023..1160	CDD:128514	134/136 (99%)
		UPA_2	1381..1510	CDD:375346	127/128 (99%)
		PTZ00121	<1611..2375	CDD:173412	573/776 (74%)
		PHA03307	1760..>2041	CDD:223039	234/288 (81%)
		PHA03307	3231..>3468	CDD:223039	160/240 (67%)
		Death_ank2	3616..3699	CDD:260066	79/82 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83695744
Domainoid	1	1.000	2973	1.000	Domainoid score	I92
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H81655
Inparanoid	1	1.050	6250	1.000	Inparanoid score	I58
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG38849
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	1	1.000	-	-		FOG0000917
OrthoInspector	1	1.000	-	-		oto140270
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1361
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	15.310