DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsd17b6 and Adhr

DIOPT Version :9

Sequence 1:	NP_775427.2	Gene:	Hsd17b6 / 286964	RGDID:	708343	Length:	327	Species:	Rattus norvegicus
Sequence 2:	NP_001027272.1	Gene:	Adhr / 3772432	FlyBaseID:	FBgn0000056	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	45/166 - (27%)
Similarity:	66/166 - (39%)	Gaps:	43/166 - (25%)

- Green bases have known domain annotations that are detailed below.

  Rat   119 LVNNAGVFQAFAYIEWCRPEDCMSIFQVNLIGLAQVTLSML-FLVKK---ARGRIVNVSSVLG-- 177
            |:|.|.:         |...:..:....||.|:.....::| ::.:|   ..|.||||:||:|
  Fly    89 LINGATL---------CDENNIDATINTNLTGMMNTVATVLPYMDRKMGGTGGLIVNVTSVIGLD 144

  Rat   178 RVALFGGFYSCSKYGVEAFSDVLRREIRD------FGVKVSIIEPGSFKTRM-TDAELIIEKTKK 235
            ...:|.. ||.||:||..|:    |.:.|      .||.|..:..|  .||: .|.||
  Fly   145 PSPVFCA-YSASKFGVIGFT----RSLADPLYYSQNGVAVMAVCCG--PTRVFVDREL------- 195

  Rat   236 TWEATPEHIRESYGQQFFDDFCNTTRRELKKCSTNL 271
              :|..|     |||.|.|.......:....|..|:
  Fly   196 --KAFLE-----YGQSFADRLRRAPCQSTSVCGQNI 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsd17b6	NP_775427.2	None
Adhr	NP_001027272.1	ADH_SDR_c_like	7..248	CDD:187584	45/166 (27%)
Adhr	NP_001027272.1	adh_short	7..195	CDD:278532	34/121 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43313
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100