Protein Alignment ddx54 and CG32344

DIOPT Version :10

• Sequence 1: NP_775375.2
• Gene: ddx54 / 286777
• ZFINID: ZDB-GENE-021220-2
• Length: 862
• Species: Danio rerio
• Sequence 2: NP_612028.4
• Gene: CG32344 / 326208
• FlyBaseID: FBgn0052344
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 878
• Identity: 366/878 - (41%)
• Similarity: 517/878 - (58%)
• Gaps: 121/878 - (13%)

Zfish    46 LPRFPA--SSECVSDVELDTRELVRAQNKKKKKSGGFQSMGLSYPVYKGIMKKGYKVPTPIQRKT 108
            :|.||:  :....||...|    :.....||.||||||||||.:.:.|||.|:||||||||||||
  Fly     9 IPGFPSLDNDAGTSDRGAD----ILKSKSKKNKSGGFQSMGLGFELIKGITKRGYKVPTPIQRKT 69

Zfish   109 IPVILDGKDVVAMARTGSGKTAAFLVPLFEKLKAPQAQTGARALILTPTRELALQTMKFTKELGK 173
            ||:||:|:||||||:|||||||.||:||||||:..:...|||||||:||||||:||.||.||||:
  Fly    70 IPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRREPTKGARALILSPTRELAVQTYKFIKELGR 134

Zfish   174 FTGLRTALILGGDSMDDQFAALHENPDIIIGTPGRLMHVIQEMNLKLQSVEYVVFDEADRLFEMG 238
            |..|::.|:|||||||.||:|:|..||:|:.||||.:|:..||:|||.|:|||||||||||||||
  Fly   135 FMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFLHLCVEMDLKLNSIEYVVFDEADRLFEMG 199

Zfish   239 FAEQLQEIIRRLPDARQTLLFSATLPKLIVEFARAGLTEPVLIRLDVDTKLSEQLKLSFFSLRLD 303
            |.|||.|.:.|||.:|||::||||||||:||||||||.:||||||||::||.:.|.|.|...|.|
  Fly   200 FGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLNDPVLIRLDVESKLPDALALKFLYCRPD 264

Zfish   304 DKPALLLHLLRNVVKPQEQTVVFVATKHHVEYLKEMLSAEGVDCSCIYSALDQTARKISIGRFVH 368
            |:...|:.||:.|:..|.|||||..|:||||.:..:|:..|:..:.:||:||..||||:..:||:
  Fly   265 DRYTALVVLLKYVIPVQSQTVVFAGTQHHVELISYILTEAGISNASVYSSLDPAARKINTAKFVN 329

Zfish   369 RKVMLLLVTDVAARGIDIPLLDNVINYNFPCKPKLFLHRVGRVARAGRGGTAYSLVCPDEVPYLY 433
            :||.:|:||||||||||||.||.|:|.:||.|||||:|||||.|||||.|||||:|..|:..:|.
  Fly   330 KKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLFVHRVGRCARAGRTGTAYSIVSTDDTAHLL 394

Zfish   434 DLHLFLGRPMQLAHPEHTQEADGVFGRVPQSVLDDEECQLITAHQNSLDLQNLRRVSENAYKQYL 498
            ||||||.||..:    |...|   .|.:||.:|::|.. .:|..:.|..:..:.|.||||||:||
  Fly   395 DLHLFLNRPFNI----HDSSA---LGTIPQDLLEEEHL-TVTDIKKSHHIAGVLRTSENAYKKYL 451

Zfish   499 KSRPVPSAESIKRSRNTQLTDMAVHPL--------------------------LGCGLEKMELDR 537
            .||||.|.::  .:|..::...|:.||                          :.....|::.::
  Fly   452 SSRPVASTDA--NARVKKIKFFALKPLEDFFTAAPVLAQAAEASGQSTESQAKVSAAERKLQEEK 514

Zfish   538 LLMVDTIKGYKAKSTIFEINSSNKTSASEVMRAKRSRDRQRVEKFSRARAELRAEPGAGLRAEPP 602
            ..::..::.::...|:||:|::.|::...||:.||.:..:.:.||.:.|||
  Fly   515 HDILVKMRSFRPGGTVFELNTTQKSTQFIVMKEKRMQHAEVINKFRQQRAE-------------- 565

Zfish   603 VHRETQEEDEE-----------------EQEELSTVFSEVVGGKR-RRPDA----EPHTHKSKKS 645
                 ::.|||                 ::|.:|:.|::||..|| :..||    :|   |.||.
  Fly   566 -----EDIDEEKKTIEALNPSSGRMPTADEEAISSTFNKVVAPKRLQNMDALYKDKP---KKKKR 622

Zfish   646 RAAGRDQEFYIPYRPKDFNSERGLSLDSGAGSFEQQASSAVLDLIGDESNTLNQHK-SLMKWDRK 709
            :...:|::.|:||:..|.::|.||:::    :||:||.:|...:...:.:...:|| .|.||||.
  Fly   623 KINSKDEDHYVPYQSADKHTEDGLAIN----NFERQAQNAEFSVSDRDLSQEVKHKPGLKKWDRI 683

Zfish   710 KKRFVRDTGKEDKHKKIRTESGQLIRGHKKKKSFYEEWKKKYKVEGGASDSDGEGGGAQRGRGSA 774
            ||:.|  :.::.:..|||||||..|.. ..|...|.|||:|.|:|.            |..|.:|
  Fly   684 KKKMV--SVQDPRANKIRTESGAWIPA-SFKTGRYAEWKEKSKIED------------QLQRENA 733

Zfish   775 GRRGRGRGRSAAGSQATPAQHQGGSGVRSELKNR-----------QQILKQRKRKAKQQFLQSGG 828
            |.... ..:..:.:|..|........::.|||.|           :||:|.|.|   .:|::...
  Fly   734 GSDDE-NAKPLSHAQRYPVSRHARHNLKLELKKRLTGNDKEMRRPEQIVKSRMR---LEFIKKRN 794

Zfish   829 MKKLRNKGKQRLREVMKSGFGRGAVKKGKMRKK 861
            .:....|.:.|.|.:.|:...:.....|..|:|
  Fly   795 EENAERKSENRKRSMRKTQRPKAQSTGGSKRRK 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ddx54	NP_775375.2	None
CG32344	NP_612028.4	DEADc_DDX54	39..243	CDD:350717	144/203 (71%)
		SrmB	41..449	CDD:440279	249/415 (60%)
		DBP10CT	<679..721	CDD:462373	20/44 (45%)