Protein Alignment P2RY8 and Hcar1

DIOPT Version :9

• Sequence 1: XP_006724506.2
• Gene: P2RY8 / 286530
• HGNCID: 15524
• Length: 548
• Species: Homo sapiens
• Sequence 2: NP_001138806.1
• Gene: Hcar1 / 689936
• RGDID: 1586364
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 91/355 - (25%)
• Similarity: 149/355 - (41%)
• Gaps: 57/355 - (16%)

Human   187 PSRMQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFM 251
            ||.|        ||.:..::....|...:|.:..|...:...||..:|...|..|.....|.|::
  Rat     6 PSAM--------DNGSCCLIEGEPITQVMPPLLILAFLLGALGNGLALCGFCFHMKTWKSSTIYL 62

Human   252 INLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLY 316
            .||:|.|.:|...||.:..|:..|.||:.|.:.|.:|......|...||:.:|.::|:|:..|::
  Rat    63 FNLAVADFLLMICLPLRTDYYLRRRHWILGDIPCRLVLFMLAMNRAGSIVFLTVVAVDRYFKVVH 127

Human   317 PLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVH--ALGIITCFDVLKWTMLPSVAMW 379
            |.........|.|.|.....|.|::     |....|....|  ..|:::..:..   ::.|...|
  Rat   128 PHHMVNAISNRTAAAIVCVLWTLVI-----LGTVYLLMESHLCVRGMVSSCESF---IMESANGW 184

Human   380 AVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNF 444
            ...:|.   |.|.:|..|.:.|....:..|.:.::...:.:.|||.....||...|:||:.|:
  Rat   185 HDIMFQ---LEFFLPLTIILFCSFKVVWSLRQRQQLTRQARMRRATRFIMVVASVFITCYLPS-- 244

Human   445 VLLAHIVSRLFY---------GKSYYHVYKLTLCLSCLNNCLDPFVYYFASREF-----QLRLRE 495
                 :::||::         ..|.:....:||.|:.||:.|||.||||:|..|     :|::|
  Rat   245 -----VLARLYFLWTVPSSACDPSVHIALHVTLSLTYLNSMLDPLVYYFSSPSFPKFYAKLKIR- 303

Human   496 YLGCRRVPRDTLDTRRESLFSARTTSVRSE 525
                      :|..||.....||    |||
  Rat   304 ----------SLKPRRPGRSQAR----RSE 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P2RY8	XP_006724506.2	7tm_4	222..>321	CDD:304433	29/98 (30%)
		7tm_1	229..482	CDD:278431	67/263 (25%)
Hcar1	NP_001138806.1	7tm_1	40..286	CDD:278431	67/263 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910