Protein Alignment P2RY8 and Gpr4

DIOPT Version :9

• Sequence 1: XP_006724506.2
• Gene: P2RY8 / 286530
• HGNCID: 15524
• Length: 548
• Species: Homo sapiens
• Sequence 2: NP_783599.1
• Gene: Gpr4 / 319197
• MGIID: 2441992
• Length: 365
• Species: Mus musculus
• Alignment Length: 359
• Identity: 102/359 - (28%)
• Similarity: 171/359 - (47%)
• Gaps: 60/359 - (16%)

Human   216 PVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVF 280
            |.:|..|..|.:|.|..:||...|::...:...::::|||:.||:....||..:.|..:..:|:.
Mouse    23 PSLYIFVIGVGLPTNCLALWAAYRQVRQHNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIH 87

Human   281 GVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALS 345
            |...|.:....||:|:|.||..:.||||:|:|.|.:||...|.||.:.|||..:..|...|.|.|
Mouse    88 GPGSCKLFGFIFYSNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANS 152

Human   346 -PLARTDL-------TYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACY 402
             ||...:|       |:         ||:  |:.|...|| | :.|:.:|: .||.|:.:.:.||
Mouse   153 APLFHDELFRDRYNHTF---------CFE--KFPMERWVA-W-MNLYRVFV-GFLFPWALMLLCY 203

Human   403 TATILKLLRTEEAHGREQ----RRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY--- 460
            .. ||:.:::..:..|::    :|.|:.|.|:||:    ||||.:.:||:.  |.::.|:.:
Mouse   204 RG-ILRAVQSSVSTERQEKVKIKRLALSLIAIVLV----CFAPYHALLLSR--SAVYLGRPWDCG 261

Human   461 -----YHVYKLTLCLSCLNNCLDPFVYYFASREFQL-------RLREYLGCRRVPRD------TL 507
                 :..|..:|..:.||...||.:|...:...:.       .|..:|...: |::      ||
Mouse   262 FEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASNK-PQEMANASLTL 325

Human   508 DTRRESLFSARTTSVRSEAG--AHPEGMEGATRP 539
            :|   .|.|.|:|:.:|...  |.|...:|...|
Mouse   326 ET---PLTSKRSTTGKSSGAVWAVPPTAQGDQVP 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P2RY8	XP_006724506.2	7tm_4	222..>321	CDD:304433	33/98 (34%)
		7tm_1	229..482	CDD:278431	81/272 (30%)
Gpr4	NP_783599.1	7tm_4	28..>145	CDD:304433	39/116 (34%)
		7tm_1	37..288	CDD:278431	81/271 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910