Protein Alignment P2RY8 and Cmklr2

DIOPT Version :9

• Sequence 1: XP_006724506.2
• Gene: P2RY8 / 286530
• HGNCID: 15524
• Length: 548
• Species: Homo sapiens
• Sequence 2: NP_037093.1
• Gene: Cmklr2 / 25457
• RGDID: 2728
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 327
• Identity: 85/327 - (25%)
• Similarity: 148/327 - (45%)
• Gaps: 44/327 - (13%)

Human   217 VVYSLVAAVSIPGNLFSLWVLCRRMG---PRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHW 278
            ::|:|...:.||||...:|.    ||   .::.:.::.:||::.|.:....||..|.|.....||
  Rat    43 LLYALAFVLGIPGNAIVIWF----MGFKWKKTVTTLWFLNLAIADFIFVLFLPLYISYVALSFHW 103

Human   279 VFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTA 343
            .||..||.:.:.....||:||:..:|.||::|::.:::|..|...|..:.::......|||....
  Rat   104 PFGRWLCKLNSFIAQLNMFSSVFFLTVISLDRYIHLIHPGLSHPHRTLKNSLLVVLFVWLLASLL 168

Human   344 LSPLARTDLTYPVHALGIITCFDVLK----WTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTA 404
            ..|......|..|:  ..|.|::..:    ..|...|..|..|||.     :|:|.:...:||..
  Rat   169 GGPTLYFRDTVEVN--NRIICYNNFQEYELTLMRHHVLTWVKFLFG-----YLLPLLTMSSCYLC 226

Human   405 TILKLLRTEEAHGREQR----RRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYK 465
            .|.|.        ::|.    .:.:.:...|::||:.|:.|  |.|.:.....:.:..|:.:|.:
  Rat   227 LIFKT--------KKQNILISSKHLWMILSVVIAFMVCWTP--FHLFSIWELSIHHNSSFQNVLQ 281

Human   466 ----LTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTL------DTRRESLFSARTT 520
                |:..|:.||:||:|.:|...|::||.|.|..:.  .|.:.:|      .|..|.|.||.|.
  Rat   282 GGIPLSTGLAFLNSCLNPILYVIISKKFQARFRASVA--EVLKRSLWEASCSGTVSEQLRSAETK 344

Human   521 SV 522
            |:
  Rat   345 SL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P2RY8	XP_006724506.2	7tm_4	222..>321	CDD:304433	29/101 (29%)
		7tm_1	229..482	CDD:278431	66/267 (25%)
Cmklr2	NP_037093.1	7tm_1	55..302	CDD:278431	66/267 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910