Protein Alignment P2RY8 and Oprk1

DIOPT Version :9

• Sequence 1: XP_006724506.2
• Gene: P2RY8 / 286530
• HGNCID: 15524
• Length: 548
• Species: Homo sapiens
• Sequence 2: NP_001305664.1
• Gene: Oprk1 / 18387
• MGIID: 97439
• Length: 409
• Species: Mus musculus
• Alignment Length: 404
• Identity: 106/404 - (26%)
• Similarity: 180/404 - (44%)
• Gaps: 61/404 - (15%)

Human   161 PGGAQTASLCLLCQGS-----WHQLESPGEDPSRMQVPNSTGPDNATLQMLR-NPAIAVALPVVY 219
            ||...:.|.|||...|     |.:.:|.|          |.|.::..|:... :|||.|.:..||
Mouse    12 PGPTCSPSACLLPNSSSWFPNWAESDSNG----------SVGSEDQQLESAHISPAIPVIITAVY 66

Human   220 SLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQ--IYYHCNRHHWVFGV 282
            |:|..|.:.||...::|:.|....::.:.|::.||::.|.::.:.:|||  :|.   .:.|.||.
Mouse    67 SVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL---MNSWPFGD 128

Human   283 LLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLL----LTA 343
            :||.:|....|.||::||.|:|.:||:|::.|.:|:.:..:|....|.......|||.    ::|
Mouse   129 VLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISA 193

Human   344 L---SPLARTDLTYPVHALGIITCF-----DVLKWTMLPSVAMWAVFL-FTIFILLFLIPFVITV 399
            :   ....|.|       :.:|.|.     |...|        |.:|: ..:|:..|:||.:|.:
Mouse   194 IVLGGTKVRED-------VDVIECSLQFPDDEYSW--------WDLFMKICVFVFAFVIPVLIII 243

Human   400 ACYTATILKLLRTEEAHGREQR----RRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSY 460
            .|||..||:|.......|..::    ||...|..||:..|:.|:.|.:..:|...:....:..:.
Mouse   244 VCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAA 308

Human   461 YHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSE 525
            ...|...:.|...|:.|:|.:|.|....|:...|::  |..:   .:...|:|....|.| |:..
Mouse   309 LSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDF--CFPI---KMRMERQSTNRVRNT-VQDP 367

Human   526 AGAHPEGMEGATRP 539
            |.....|  |..:|
Mouse   368 ASMRDVG--GMNKP 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P2RY8	XP_006724506.2	7tm_4	222..>321	CDD:304433	32/100 (32%)
		7tm_1	229..482	CDD:278431	70/271 (26%)
Oprk1	NP_001305664.1	7tm_4	70..312	CDD:304433	66/259 (25%)
		7tm_1	76..330	CDD:278431	70/271 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910