Protein Alignment DTWD2 and Dtwd2

DIOPT Version :10

• Sequence 1: XP_011541640.3
• Gene: DTWD2 / 285605
• HGNCID: 19334
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_649713.1
• Gene: Dtwd2 / 40873
• FlyBaseID: FBgn0037492
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 110/269 - (40%)
• Similarity: 146/269 - (54%)
• Gaps: 28/269 - (10%)

Human    48 DDDSADGLWELPVEPAERRPECTRCSRPQKVCLCPFLPAHPLHISTHLYIIQHPAEENKVLRTVP 112
            :||:...|..:..:|..||.:|.:|.||..||.||.||..|..:|:.:.|:||||||.:.|||..
  Fly     2 EDDAWLDLVGISADPPNRRNKCEKCKRPVVVCWCPALPHPPEAVSSQIVILQHPAEEKRSLRTAL 66

Human   113 LLAACLPQDKCKVKIGRRFSEERD-PELSTVCRKSGTLILYPGAEAANLEEFILDSPVYPSTIII 176
            :|...|...||.|..|:||...|: .:|..:.....||:|||..::..|||  :|....|.|:::
  Fly    67 MLQLGLEPGKCVVYKGKRFPNHRNHADLQRILDSPQTLLLYPSRDSVPLEE--VDHSAGPYTLVL 129

Human   177 IDGTWSQAKDIFYKNSLFRHPKQQEDFHLQARKRALTRTVTMQVQLKTSISSQYVIRMQPTNRCL 241
            |||||.|||.|:                  |...||.|  ..||:|.....|.|:||.|||..||
  Fly   130 IDGTWPQAKAIY------------------ASSPALHR--LRQVKLIAVGISDYIIRTQPTEGCL 174

Human   242 STLECAAVALSILEKNNYIQETLLRPLQALCSFQLQHGAQIRLSKEHLLKNGLYPKPMPKNKRKL 306
            ||||.||..|::||....:::||:|||..||.:||.:||....|||.||||..||||:.|
  Fly   175 STLETAAQCLAVLESRPELRQTLVRPLHTLCKYQLDNGAVEHQSKEFLLKNNQYPKPIGK----- 234

Human   307 RKMELLMNS 315
            |...||.|:
  Fly   235 RLSRLLRNT 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DTWD2	XP_011541640.3	DTW	66..276	CDD:461101	85/210 (40%)
Dtwd2	NP_649713.1	DTW	20..209	CDD:461101	85/210 (40%)