Protein Alignment SH3PXD2B and cindr

DIOPT Version :9

• Sequence 1: XP_016864840.1
• Gene: SH3PXD2B / 285590
• HGNCID: 29242
• Length: 939
• Species: Homo sapiens
• Sequence 2: NP_001263129.1
• Gene: cindr / 43654
• FlyBaseID: FBgn0027598
• Length: 941
• Species: Drosophila melanogaster
• Alignment Length: 836
• Identity: 169/836 - (20%)
• Similarity: 261/836 - (31%)
• Gaps: 247/836 - (29%)

Human   158 VVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEG----------QDGV 212
            :|...|..:|..|:.|..|.::..|::...|||       ||.:.|:.:.|          :.||
  Fly     8 IVEYEYAAKEPDELDLQKGAIIHRIKQMPGGWW-------QGTLKASGVTGMFPDNFVRVLESGV 65

Human   213 Q----------DEFSLQPEEVSWRYWSLPRPVGRRRTLGDLYAISWRQEEKYTVIYPYTARDQDE 267
            .          |...                ||....|.|..|.|.|   :..|||.||..:.||
  Fly    66 SSNGNGTTGSGDHIE----------------VGTAVQLRDKSATSNR---RCKVIYSYTQVNDDE 111

Human   268 MNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVS 332
            :.|..|.|:|.:.:..||||:.|.:.|.|..|:::::..  ||.|.......|:....:....::
  Fly   112 LTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHI--EPSPVLASKRPPTIGATVTTSALT 174

Human   333 RQQNAVGREKELLSSQRDGRFEGRPVPDGDA-----------------KQRSPKMRQRPPPRRDM 380
            .:...|.......:           ||.|.|                 |.|:........|....
  Fly   175 SKAANVANVAATAT-----------VPTGGAVPPASTSISTSTTKQATKSRATAAAAASAPAEPA 228

Human   381 TIPRGLNLPK--------PPIPPQVEEEYYTIA---------EFQTTIPDGISFQAGLKVEVIEK 428
            .|..|.....        |.:||:.:.|:..:.         |.:..:.|.|   |.:..|:.:|
  Fly   229 AIVSGSGAAAGGGAAAAVPMLPPKPQREFCRVEFPYAPQNDDELELKVDDII---AVISTELPDK 290

Human   429 NLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATG 493
               |||..:|..|.|..|..|:.....:...:.|    |||....:.|.|        .|....|
  Fly   291 ---GWWKGEIRGKVGVFPDNFVKMLAPSEATAAP----PLPRPRPRTRPG--------MGGTGAG 340

Human   494 PSRPLPDAPHGVMDS-GLPWSKDWKGSKDVL--RKASSDMSASAGYEEISDPDMEEKPSLPPRKE 555
                   :..|::|. ..|......||.:.|  |.||   ..:..:..|::|....:.:...||.
  Fly   341 -------SGSGIIDGVRTPRRTQRGGSFEFLGARMAS---FITTIFAPINEPPSATQITQNQRKV 395

Human   556 S----------IIKSEGELLERERERQRTEQLRGPTP-------KPPGVILPMMPAKHIPPARDS 603
            |          ...|..........:|:.||:.|.:.       |..|.......:.....:..:
  Fly   396 SNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSA 460

Human   604 RRPEPKPDKSRLFQLKNDMGLECGHKVLA--KEVKKPNL---RP--------------------- 642
            .|.|....:..|..:.::.||..|: |.|  |.::..||   :|
  Fly   461 GRKESFGSRDSLNDILSETGLPTGN-VAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATT 524

Human   643 --------------ISKSKTDLPEEKPDATPQNPFLKSRPQVRPKPAPS---PKTEPPQGEDQVD 690
                          :|||..::.:||..:.|. |.|..:|.|..|..|:   |.|....|..:.
  Fly   525 SSATTVATGLTSSSVSKSMENMLDEKVKSPPP-PVLSKKPSVPLKKTPTGGVPMTGNLLGGKKK- 587

Human   691 ICNLRSKLRPAKSQDKSLLDGEGPQAVGGQDVAFSRSFLPGEGPGRAQDRTGKQDGLSPKEISCR 755
              |...||..|.|.|  |.||     :....:....:.||             :.|.:...:..|
  Fly   588 --NTEGKLTTAVSHD--LADG-----LAASKMLSGANQLP-------------ESGAAGNVVIRR 630

Human   756 APPRPAKTTDPVSKSVPVPLQEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAP 820
            |.....:.||.........|.:..|.|...|.||||     |::...|.|..
  Fly   631 AATIAVEDTDFDRVERASILTDMRQGRVKAPKRRPP-----SAAINVLGESN------------- 677

Human   821 TPGRALLVPPKAKPFLSNSLGGQDDTRGKGSLGPWGTGKIGENREKAAAASVPNAD 876
                            :||:    ...|.|..|..|.|...|..|...|....:.|
  Fly   678 ----------------NNSV----YVNGSGMSGSGGAGSASELSEDGGAGGKTSDD 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3PXD2B	XP_016864840.1	None
cindr	NP_001263129.1	SH3_CD2AP-like_1	6..60	CDD:212806	14/58 (24%)
		SH3_CD2AP-like_2	97..149	CDD:212807	19/51 (37%)
		SH3_CD2AP-like_3	258..310	CDD:212808	14/57 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	64	1.000	Inparanoid score	I5371
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050