Protein Alignment FRYL and fry

DIOPT Version :10

• Sequence 1: XP_024309756.1
• Gene: FRYL / 285527
• HGNCID: 29127
• Length: 3120
• Species: Homo sapiens
• Sequence 2: NP_001246701.1
• Gene: fry / 39122
• FlyBaseID: FBgn0016081
• Length: 3544
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 106/533 - (19%)
• Similarity: 165/533 - (30%)
• Gaps: 222/533 - (41%)

Human  1420 VDALWIENMNTVLDDNKMLCLANSERIKLTPQIHM------LFE--VQD-----LRVASP----- 1466
            :|:....|..:.|:..|:....|.:|.|.|...||      :||  ||.     |.|..|
  Fly    63 IDSFLSVNRESSLNKFKLRIYCNHDRDKETNNAHMARWISAIFEQNVQHVDRTWLPVEVPPILYL 127

Human  1467 ----ATVSRCGMVFVDPEELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCS 1527
                .|:..||:|..: .|..::|.||                 :|.|      |.:.|.|
  Fly   128 CESLVTLRLCGVVLAN-LEFMYLPLVK-----------------VLAL------EWVIFAN---- 164

Human  1528 QAIPQVDISKVTTLCCLLESLILGK---DGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYY 1589
                ::.:.|:.:.|.:||||...|   |.||:...:::               ||   |:.|||
  Fly   165 ----ELALEKLISGCLVLESLSFCKCSLDNVNVLRVRSQ---------------SL---LSFNYY 207

Human  1590 DSFDTFIRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDT 1654
            .                  |:|.||                             .|:.||.|.|.
  Fly   208 G------------------PSSRDL-----------------------------HFKDLVVTIDA 225

Human  1655 VRYGYLMEKLLAVKH----SVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQ 1715
            .:.     ::|.:.|    .|.|...  |||......|..:        .:.|:|....|..:..
  Fly   226 PKL-----EILKLSHQANIKVEFNFC--VGKKFNPNDLSKR--------KMILHFLVAISRVKNM 275

Human  1716 EIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQ--------YQDFGGFY 1772
            .|..|.||                |..|         |....|:.|.|.        |||
  Fly   276 TIAASTLE----------------IIYD---------YSRCEPVPLFRDISLLRVEFYQD----- 310

Human  1773 DRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHF-SMLCLPMPSEHSLKQIFQAILNGFLSD 1836
                                     |..:.|.|:... ::..|.:.|::..|:     ....||
  Fly   311 -------------------------RWEILPFFLESCPNVKSLVVESDYYTKE-----RTSILS- 344

Human  1837 FPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFN---LRDLSKCVQGILQCDPGTIREEI 1898
               ..::..||:....:    |.|.|.|.....|:::.|   |:.::.|:.|..:.:...:||.:
  Fly   345 ---RPRRLLSSLEYVKI----KSSWDKLEMKLVSYFIENSPILKKVTLCLDGCSRKESVILRELL 402

Human  1899 QIFRLFCHECQRV 1911
            .|.|| ...||.|
  Fly   403 TIPRL-SSSCQVV 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRYL	XP_024309756.1	MOR2-PAG1_N	209..756	CDD:464107
		MOR2-PAG1_mid	788..1966	CDD:433790	106/533 (20%)
		MOR2-PAG1_C	2108..2361	CDD:464109
		Fry_C	2391..3120	CDD:466072
fry	NP_001246701.1	MOR2-PAG1_N	389..922	CDD:464107	9/27 (33%)
		MOR2-PAG1_mid	1326..2330	CDD:433790
		MOR2-PAG1_C	2501..2753	CDD:464109
		Fry_C	2785..3439	CDD:466072