Protein Alignment PRRT3 and GPR1

DIOPT Version :10

• Sequence 1: NP_997234.3
• Gene: PRRT3 / 285368
• HGNCID: 26591
• Length: 981
• Species: Homo sapiens
• Sequence 2: NP_010249.1
• Gene: GPR1 / 851527
• SGDID: S000002193
• Length: 961
• Species: Saccharomyces cerevisiae
• Alignment Length: 174
• Identity: 38/174 - (21%)
• Similarity: 56/174 - (32%)
• Gaps: 43/174 - (24%)

Human   664 GPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRLACPAPSGKSE 728
            |.|..|:..| ::..:|.|.||.|...|. ....::...|...|:              .||.|.
Yeast   302 GLGHWGKAKW-YFRSYFKLPLLHLLRNLK-NFFTISFIDPNEETD--------------DSGSSN 350

Human   729 VPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGA----WGSAASLGRGPQG---GP 786
                      |..|.|..|.:|.....:....|.:..:.|.|.    :.||..|......   .|
Yeast   351 ----------GTFNFGESSNEIPTLFRKTNTGSDENVSASGGVRLLDYNSAKPLDMSKYAMSEQP 405

Human   787 GLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSV 830
            .|.||  .|....:::.|.|...::..        :||.|..||
Yeast   406 DLERN--NPFDCENDITLNPSELVSKQ--------KEHKVTFSV 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRRT3	NP_997234.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..107
		PHA03247	<84..468	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..457
		O-glycosylated at one site	297..302
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..807		12/54 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	836..865
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	937..981
GPR1	NP_010249.1	Git3	52..279	CDD:371685
		TM helix 2	85..106	CDD:320094
		TM helix 3	127..149	CDD:320094
		TM helix 4	180..196	CDD:320094
		TM helix 5	239..264	CDD:320094
		GPR_Gpa2_C	610..685	CDD:371826