Protein Alignment PRRT3 and Prrt3

DIOPT Version :10

• Sequence 1: NP_997234.3
• Gene: PRRT3 / 285368
• HGNCID: 26591
• Length: 981
• Species: Homo sapiens
• Sequence 2: NP_001296392.1
• Gene: Prrt3 / 502873
• RGDID: 1562419
• Length: 978
• Species: Rattus norvegicus
• Alignment Length: 989
• Identity: 742/989 - (75%)
• Similarity: 791/989 - (79%)
• Gaps: 19/989 - (1%)

Human     1 MASSPWGCVCGLLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENP 65
            ||.||..|...|||||||.||.||||.||.||||||||..:||         |||:.||:|.|..
  Rat     1 MAPSPQACASPLLLLLLPCLGAGPALVRGLPRPLENSEPHVIP---------SEPRTFDLFWEKL 56

Human    66 RADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQG-AQRERLPVTDDLQMAQGPSSHGWTG 129
            ..:|.|:|....|.||. |::|..|||||||:|||.|.| .|.|||...||||:|:..:|.||||
  Rat    57 DNESSRHSGTPQAHAEG-PKRPADSPLGPALHGPKVAPGVVQGERLLRADDLQLARALTSQGWTG 120

Human   130 PLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHE-GQEGQWPPRDEGLKAKTK 193
            |.||||||:.||..|||:|.||||.:||||..||.|||:..:.|.. |..||.|||||||.||.|
  Rat   121 PPDSQELLETEAPEPHPMGAPHLTLVPTTPSFQLTVATLDTASQKPGGPAGQQPPRDEGLMAKAK 185

Human   194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVP-- 256
            :.. ...|..:||.||.||..:|.|:..||..|||.|:.||||.|||..||||||.|:|||.|
  Rat   186 THT-QALPWGYQGSPHILVPETGAVRTLVLGKQGGHEQGLQEAVQGPLLTQQDPATPEVGSTPPV 249

Human   257 --PVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSP 319
              ||||..:.|||.|.|.|||||||..|.||.|..|:.||..:|||||.||.|:|.|....:|||
  Rat   250 EAPVEVKSTPEPGTQLDRALARSLPLPEGLPAEPSKKGGAGDTWEVSSLGPQPEQTDHHGGQDSP 314

Human   320 GPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESP 384
            .|.|..|.||:..|...:|..|:|||.|||||||||||:||||||||.||...:...|.|.||||
  Rat   315 APPPIPPAASDISDGHLRPAIASMNGVDPISPQRVRGAMEAPGTPKSFIPDLLNSAQAANGTESP 379

Human   385 MGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSP 449
            |.|||||||||||||||||||||||||||||||||::|||||||||||||||:||||...|||||
  Rat   380 MRALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLVKVTTQRALGQPPPPEPSASSMVPIPASSP 444

Human   450 PANATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALAALAAAPAGPRLALVAAVLVLVAS 514
            |||||||||||||||||||||||||||||||||||||||||..||||.|||||||||||||||||
  Rat   445 PANATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALVTLAAALAGPRLALVAAVLVLVAS 509

Human   515 ALRSAYMLTDPYGSQARLGVRGGLVLYNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVAL 579
            .||||||||||||||||||||.|||||||||||||||||||||||||||||.|||.|||||.||.
  Rat   510 GLRSAYMLTDPYGSQARLGVRAGLVLYNLPFPLLLTALAALTLLGLGAGLPQPLQKPLLLGVVAP 574

Human   580 VHGVGLLATDLLSTWSVLNLLTQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAG 644
            |||.|||||||.||..|||||||||||||||:||||||||||||||:||||||||||||||||||
  Rat   575 VHGAGLLATDLFSTSPVLNLLTQGLSCAWGASVALGTLCLCRRRLLEGPRGWDASPGPRLLAVAG 639

Human   645 ALGLLASGLQLAAALWLYPGPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEH 709
            :||||||||||||:|||||||||.|||||||||||||||||||||||||||||:||.||||||||
  Rat   640 SLGLLASGLQLAASLWLYPGPGREGRFSWAWWGVHFWLRLLELTWALALALAALAATRPRPPTEH 704

Human   710 ACWAKLMRLACPAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPA-ESGQLATPSSGAWG 773
            ||||||:|||||||:|||||||||||||||||.||.|.||||||||||.| |.|..|||.||.||
  Rat   705 ACWAKLLRLACPAPTGKSEVPERPNNCYAGPSGVGTGGLDISKSLIRNAAGEGGLPATPGSGPWG 769

Human   774 SAASLGRGPQGGPGLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRG 838
            ||||||||..||||:||..|||||||||||||||||||||||||||||||||||||||.||||||
  Rat   770 SAASLGRGRPGGPGMSRGSVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFHRCGLRG 834

Human   839 LASPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRVRGPVPQHVVEAPDGAAAA-ASGS 902
            |||.||||||||||||.|.||||.||:|||||||||||:|.:|..:|||||..|.||||| .|||
  Rat   835 LASSPPGGALRPRRGSQPDAELDGAGTSLLRGRCRSLSEVCLRTSLPQHVVNPPVGAAAAGTSGS 899

Human   903 SLDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPAPTPAPDSTAARQGDGQGEVQPRGK 967
            ||||||:|||||||||||||||||||||||||||||||||.|||||....||.|:.|||.|||.|
  Rat   900 SLDSFSKGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPPPTPAPAPAPARAGEPQGEGQPRCK 964

Human   968 PGESRSASSDTIEL 981
            ..||.|||||||||
  Rat   965 SSESHSASSDTIEL 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRRT3	NP_997234.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..107		28/64 (44%)
		PHA03247	<84..468	CDD:223021	250/389 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..457		185/292 (63%)
		O-glycosylated at one site	297..302		3/4 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..807		37/48 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	836..865		24/28 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	937..981		30/43 (70%)
Prrt3	NP_001296392.1	PHA03247	<64..468	CDD:223021	259/405 (64%)