Protein Alignment SUMF1 and Sumf1

DIOPT Version :10

• Sequence 1: XP_011531926.1
• Gene: SUMF1 / 285362
• HGNCID: 20376
• Length: 448
• Species: Homo sapiens
• Sequence 2: XP_006506507.1
• Gene: Sumf1 / 58911
• MGIID: 1889844
• Length: 409
• Species: Mus musculus
• Alignment Length: 422
• Identity: 295/422 - (69%)
• Similarity: 317/422 - (75%)
• Gaps: 33/422 - (7%)

Human     1 MAAPALGLVCGRCPELGLVLLLLLLSLLCGAAGSQEAGTGAGAGSLAGSCGCGTPQRPGAHGSSA 65
            |||||.......|..|..|.|||:|:  |..|||.||....||.|||||||||||||.|||||||
Mouse     1 MAAPAREPALRCCIRLARVFLLLVLA--CEVAGSDEAEAREGAASLAGSCGCGTPQRAGAHGSSA 63

Human    66 AAHRYSREANAPGPVPGERQLAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYE 130
            ||.||||||||||...|.|.||.:|||||||||||||||||||:|||||||||||:|.|||||||
Mouse    64 AAQRYSREANAPGLTSGPRPLALTKMVPIPAGVFTMGTDDPQIRQDGEAPARRVTVDGFYMDAYE 128

Human   131 VSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTNIQQAVAAAPWWLPVKGANWRHPEGPD 195
            |||.:|||||||||||||||||||||||||||||||||:|.||||||||||||||||||||||||
Mouse   129 VSNADFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTHIHQAVAAAPWWLPVKGANWRHPEGPD 193

Human   196 STILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANI 260
            |:||||.:||||||||||||||||||||||||||||||||||||.||||||||||||||||||||
Mouse   194 SSILHRSNHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLQNRLFPWGNKLQPKGQHYANI 258

Human   261 WQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKG----- 320
            |||:|||:|||||||||||||||||||||||||||||.|||||||||||||||||.||.|
Mouse   259 WQGKFPVSNTGEDGFQGTAPVDAFPPNGYGLYNIVGNVWEWTSDWWTVHHSVEETFNPSGLVVVV 323

Human   321 ---PPSGKDRVKKGGSYMCHRSQEYYDPYFQDVASEMLRRHTASRWKAFSSLE---PCCSIRRHQ 379
               |.|..:::.:... :|..|.   .|.:|||.           |:..|..|   ||    :.:
Mouse   324 VKQPVSPSEKIVQTWG-VCAWSP---SPCWQDVT-----------WRLLSEAEIDFPC----QIK 369

Human   380 QYAAIERLTCGKFELRCAEAQRLSLPPCGANG 411
            ..|.:|....|...|...|...||: .|||.|
Mouse   370 ASACLEGAVQGSRILASCECSYLSI-CCGAQG 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SUMF1	XP_011531926.1	FGE-sulfatase	91..347	CDD:397722	219/263 (83%)
Sumf1	XP_006506507.1	FGE-sulfatase	86..317	CDD:397722	213/230 (93%)