DRSC/TRiP Functional Genomics Resources

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Protein Alignment GPER1 and frpr-10

DIOPT Version :9

Sequence 1:NP_001035055.1 Gene:GPER1 / 2852 HGNCID:4485 Length:375 Species:Homo sapiens
Sequence 2:NP_001379889.1 Gene:frpr-10 / 186481 WormBaseID:WBGene00019019 Length:292 Species:Caenorhabditis elegans


Alignment Length:260 Identity:56/260 - (21%)
Similarity:103/260 - (39%) Gaps:56/260 - (21%)


- Green bases have known domain annotations that are detailed below.


Human   108 LVADSLIEVFNLHER-----------YYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALAR 161
            ::..|:.:...:||.           ::.:.|....:||..|.   .||:....::.||:||:..
 Worm     1 MIYPSMHQCSTIHETEQRLNSSVCHFFWRVTVSIFPLSLIAQA---GSVWTYVAVTVDRFIAVCF 62

Human   162 AMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEACFCFADVREVQ----------- 215
            .::..::.|:.:......:|...|....|..|..|.|.|..|     .:..|::           
 Worm    63 PIKRRVWSTRSNTITVLFVITFISAIFKLPSFFEVRLDHNGE-----VEPTELRKNEFYIEFYLF 122

Human   216 WLEVTLGFIVPFAIIGLCYSLI---VRVLVRA-----HRHRGLRPRRQKALR----MILAVVLVF 268
            :|.||...::|:.:|....::|   ||:..||     |....|..:|:.|.|    |...:.::|
 Worm   123 YLYVTFIQLIPWTLIIFLNAIIIHKVRLAYRAQEAMVHNSGKLNTKREDAERKVTVMATVMTMIF 187

Human   269 FVCWLPENVFISVHLLQR-TQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLIYSFLGETFR 332
            .:|.:|..:   .:|:.| :.|..      :|...||:    |:....||..|.:||......||
 Worm   188 IICNIPPGI---NYLVDRYSNPTV------YRQRIPLS----NVLVCVNSASNMMIYCVFNSRFR 239

Human   333  332
             Worm   240  239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GPER1NP_001035055.1 7tmA_GPER1 60..335 CDD:320120 56/260 (22%)
TM helix 1 62..86 CDD:320120
TM helix 2 95..116 CDD:320120 1/7 (14%)
TM helix 3 131..153 CDD:320120 5/21 (24%)
TM helix 4 176..192 CDD:320120 3/15 (20%)
TM helix 5 212..235 CDD:320120 6/33 (18%)
TM helix 6 258..280 CDD:320120 5/25 (20%)
TM helix 7 303..328 CDD:320120 8/24 (33%)
frpr-10NP_001379889.1 7tmA_FMRFamide_R-like <20..242 CDD:410630 53/241 (22%)
TM helix 3 32..54 CDD:410630 6/24 (25%)
TM helix 4 77..93 CDD:410630 3/15 (20%)
TM helix 5 119..142 CDD:410630 5/22 (23%)
TM helix 6 177..199 CDD:410630 4/24 (17%)
TM helix 7 210..235 CDD:410630 9/28 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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