DRSC/TRiP Functional Genomics Resources

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Protein Alignment GPER1 and frpr-4

DIOPT Version :9

Sequence 1:NP_001035055.1 Gene:GPER1 / 2852 HGNCID:4485 Length:375 Species:Homo sapiens
Sequence 2:NP_001309544.1 Gene:frpr-4 / 183763 WormBaseID:WBGene00016909 Length:362 Species:Caenorhabditis elegans


Alignment Length:323 Identity:61/323 - (18%)
Similarity:127/323 - (39%) Gaps:56/323 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    72 IGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSL-------IEVFNLHERYYDIAVL 129
            ||.:||:|.|.. .|.:.:.::......:|:|:|:.|:..:|       :.::...:|.:.:|..
 Worm    21 IGLLGNLLSLYA-YSRKNRKSMVGFLLYSLSVSDIFLLVFALPLFSIMYLPIWTDEQRSFVVAYT 84

Human   130 CTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFT 194
            ..::.....:....|::.:..::.:|:||:.|.:...::.....:..|...|...:|......|.
 Worm    85 AKYVYPLCMMAKTCSLYIMVLITIERWIAVCRPLEVQIWCRYTTSSYSIAAIITFAVVLNFARFF 149

Human   195 AVHLQHTDEACFCFADV--REVQW---------LEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHR 248
            ...:::.|...|...|:  .|..|         :.:...::|||.|:.:...||:..|.|..:.|
 Worm   150 EFEIEYIDGLAFFRRDLLDSEKHWWYFMFYFIIISIIFDYLVPFVIMFVANMLIISELRRTKKER 214

Human   249 GL----RPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSF-------RHAH 302
            .|    :.:.|....|:|.:.:.|..|.     |.|:         |....:||       ::.:
 Worm   215 SLMTIQQQKEQNTTVMLLVITIFFGFCH-----FFSM---------ALKLAESFVGKFLTIQNIY 265

Human   303 -PLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDST 364
             .:.|.|.|.....::.....||....|.||..::       .:...:::.|.:|    ||.|
 Worm   266 LEMLGEIFNYLIIIHTASTFFIYYMFSEKFRQIIK-------GIWKPDQYRHGSL----PDGT 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GPER1NP_001035055.1 7tmA_GPER1 60..335 CDD:320120 56/292 (19%)
TM helix 1 62..86 CDD:320120 6/13 (46%)
TM helix 2 95..116 CDD:320120 5/27 (19%)
TM helix 3 131..153 CDD:320120 1/21 (5%)
TM helix 4 176..192 CDD:320120 3/15 (20%)
TM helix 5 212..235 CDD:320120 6/31 (19%)
TM helix 6 258..280 CDD:320120 5/21 (24%)
TM helix 7 303..328 CDD:320120 5/24 (21%)
frpr-4NP_001309544.1 7tmA_FMRFamide_R-like 33..299 CDD:320109 50/279 (18%)
TM helix 2 43..65 CDD:320109 5/21 (24%)
TM helix 3 86..108 CDD:320109 1/21 (5%)
TM helix 4 131..147 CDD:320109 3/15 (20%)
TM helix 5 178..201 CDD:320109 4/22 (18%)
TM helix 6 225..250 CDD:320109 8/38 (21%)
TM helix 7 265..292 CDD:320109 5/26 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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