| Sequence 1: | NP_005609.3 | Gene: | DLL1 / 28514 | HGNCID: | 2908 | Length: | 723 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001247193.1 | Gene: | Dl / 42313 | FlyBaseID: | FBgn0000463 | Length: | 833 | Species: | Drosophila melanogaster |
| Alignment Length: | 776 | Identity: | 304/776 - (39%) |
|---|---|---|---|
| Similarity: | 395/776 - (50%) | Gaps: | 98/776 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Human 4 RCALALAVLSALLCQVWSSGVFELKLQEFVNKKGLLGNRNCCRG---GA-GPPPCACRTFFRVCL 64
Human 65 KHYQASVSPEPPCTYGSAVTPVLGVDSFSLPDGGG-ADSAFSNPIRFPFGFTWPGTFSLIIEALH 128
Human 129 TDSPDDLATENPERLISRLATQRHLTVGEEWSQDLHSSGRTDLKYSYRFVCDEHYYGEGCSVFCR 193
Human 194 PRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECI 258
Human 259 RYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGA 323
Human 324 TCELGIDECDP--SPCKNGGSCTD---LENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSD 383
Human 384 SPDG------GYSCRCPVGYSGFNCEKKIDYCSSSP----------------------------- 413
Human 414 ------CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPG 472
Human 473 YTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVD-----L 532
Human 533 TEKLEGQGGPFPWVAVCAGVILVLMLLLG--CAAVVVCVRLRLQKHRPPADPCRGETETMNNLAN 595
Human 596 CQREKDISVSIIGATQ---------------------IKNTNKKADFHGDHSADKNGFKARYPAV 639
Human 640 DYNLVQDLKGDDTAVRDAHSKRDTKC---QPQGSSGEEKGTPTTL--RGGEASERKRPDSG 695 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DLL1 | NP_005609.3 | MNNL | 22..92 | CDD:311545 | 35/73 (48%) |
| DSL | 159..221 | CDD:128366 | 32/61 (52%) | ||
| EGF_CA | 288..326 | CDD:238011 | 26/37 (70%) | ||
| EGF_CA | 329..364 | CDD:238011 | 16/39 (41%) | ||
| EGF_CA | <373..403 | CDD:238011 | 15/35 (43%) | ||
| EGF_CA | 406..440 | CDD:238011 | 15/68 (22%) | ||
| EGF_CA | 443..478 | CDD:238011 | 19/34 (56%) | ||
| EGF_CA | <489..517 | CDD:238011 | 13/27 (48%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 653..702 | 12/48 (25%) | |||
| Interaction with MAGI1. /evidence=ECO:0000250|UniProtKB:Q61483 | 720..723 | ||||
| Dl | NP_001247193.1 | MNNL | 23..96 | CDD:284966 | 35/72 (49%) |
| DSL | 164..226 | CDD:279722 | 32/61 (52%) | ||
| EGF_CA | 291..329 | CDD:238011 | 26/37 (70%) | ||
| EGF_CA | 337..372 | CDD:238011 | 13/34 (38%) | ||
| EGF_CA | 453..488 | CDD:238011 | 11/34 (32%) | ||
| EGF_CA | 492..526 | CDD:238011 | 19/33 (58%) | ||
| EGF_CA | 529..564 | CDD:238011 | 14/34 (41%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165144843 | |
| Domainoid | 1 | 1.000 | 114 | 1.000 | Domainoid score | I6068 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BEE5 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H4104 | |
| Inparanoid | 1 | 1.050 | 566 | 1.000 | Inparanoid score | I1081 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5376 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D197806at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002026 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41486 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104568 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4539 |
| SonicParanoid | 1 | 1.000 | - | - | X1332 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.640 | |||||