Protein Alignment NKIRAS2 and kappaB-Ras

DIOPT Version :10

• Sequence 1: NP_060065.2
• Gene: NKIRAS2 / 28511
• HGNCID: 17898
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_610278.1
• Gene: kappaB-Ras / 35667
• FlyBaseID: FBgn0040513
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 189
• Identity: 76/189 - (40%)
• Similarity: 114/189 - (60%)
• Gaps: 10/189 - (5%)

Human     1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDR-GVREQVRFYDTRG 64
            :||..||:|||...||||:::|||:||:....:|:..|.|||||.|::|.| |.||.:|.|||.|
  Fly     6 IGKVGKVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIYVASVDTGRGGARETLRIYDTAG 70

Human    65 LR-DGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQR 128
            |: :..:||||.....|.:||||......|...:..:|.:|:|.|:|||:.:|||.|   ::.:.
  Fly    71 LQGEQQQLPRHYLQFPDAFVLVYDPMDPRSLDMLADIKADIEKHKEKKEIPVVVLAN---VRARA 132

Human   129 RVDP-----DVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRK 182
            ..:|     |.|..|.:.|::|.:.|:..:|.||.|||..|.:::...|:||.||..|:
  Fly   133 APNPVEKVMDRANIWCQRERIKHYTVNAMERPSLYEPFTTLCARLHPMQTKSTFPQLRQ 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKIRAS2	NP_060065.2	Small GTPase-like	1..191		76/189 (40%)
		P-loop containing Nucleoside Triphosphate Hydrolases	6..168	CDD:476819	68/168 (40%)
		Effector region	35..43		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..191		6/14 (43%)
kappaB-Ras	NP_610278.1	Ras_like_GTPase	13..174	CDD:206648	65/163 (40%)