Protein Alignment RNF149 and Rnf149

DIOPT Version :9

• Sequence 1: XP_005263977.1
• Gene: RNF149 / 284996
• HGNCID: 23137
• Length: 428
• Species: Homo sapiens
• Sequence 2: NP_001028307.2
• Gene: Rnf149 / 67702
• MGIID: 2677438
• Length: 394
• Species: Mus musculus
• Alignment Length: 388
• Identity: 303/388 - (78%)
• Similarity: 328/388 - (84%)
• Gaps: 8/388 - (2%)

Human     1 MAWRRREAS-VGARGVLALALLALALCVPGARGRALEWFSAVVNIEYVDPQTNLTVWSVSESGRF 64
            ||.|||.|: ||||.  |||:||||||.||..|.||||:||:|:|||||||:|||||||||||||
Mouse     1 MAARRRPAAGVGARD--ALAVLALALCTPGVGGGALEWYSAMVSIEYVDPQSNLTVWSVSESGRF 63

Human    65 GDSSPKEGAHGLVGVPWAPGGDLEGCAPDTRFFVPEPGGRGAAPWVALVARGGCTFKDKVLVAAR 129
            |:||.:|...||||||.|| ...|||||||||..  ||..|.|||||||||||||||||||.|||
Mouse    64 GESSLREERQGLVGVPRAP-APAEGCAPDTRFVA--PGALGNAPWVALVARGGCTFKDKVLAAAR 125

Human   130 RNASAVVLYNEERYGNITLPMSHAGTGNIVVIMISYPKGREILELVQKGIPVTMTIGVGTRHVQE 194
            |||||||:||.|..||.|.|||||||||||||||||||||||.:||||||||.|.|.:||||:||
Mouse   126 RNASAVVVYNLESNGNATEPMSHAGTGNIVVIMISYPKGREIFDLVQKGIPVKMRIEIGTRHMQE 190

Human   195 FISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQIGSQSHRKETKKVIGQLLLHTVKHGE 259
            |||||||||||||||||||||||||||||||||||||||.|||:||||||||||||.||||||||
Mouse   191 FISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQNHRKETKKVIGQLPLHTVKHGE 255

Human   260 KGIDVDAENCAVCIENFKVKDIIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGEPG 324
            |||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||:|.
Mouse   256 KGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPE 320

Human   325 DVQEMPAPESPPGRDPAANLSLALPDDDGSDDSSPPSASPAESEPQCDPSFKGDAGENTALLG 387
            |.||:|.||:.|||....|||:...|::.| :|:.||:|.:||.|. .|..|.||||:|||||
Mouse   321 DTQELPTPEAAPGRVSVGNLSVTSQDEERS-ESNLPSSSSSESGPH-RPCLKEDAGEDTALLG 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF149	XP_005263977.1	PA_GRAIL_like	43..185	CDD:239037	111/141 (79%)
		UPF0233	<204..>235	CDD:299753	30/30 (100%)
		zf-RING_2	267..310	CDD:290367	41/42 (98%)
Rnf149	NP_001028307.2	PA_GRAIL_like	45..181	CDD:239037	109/138 (79%)
		UPF0233	<193..>220	CDD:299753	26/26 (100%)
		zf-RING_2	263..306	CDD:290367	41/42 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..394		32/63 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83973095
Domainoid	1	1.000	102	1.000	Domainoid score	I44608
eggNOG	1	0.900	-	-		E1_KOG4628
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H18337
Inparanoid	1	1.050	599	1.000	Inparanoid score	I10606
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG37272
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		oto128267
orthoMCL	1	0.900	-	-		OOG6_119631
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	16.260