DRSC/TRiP Functional Genomics Resources

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Protein Alignment LAMA1 and alp7

DIOPT Version :9

Sequence 1:NP_005550.2 Gene:LAMA1 / 284217 HGNCID:6481 Length:3075 Species:Homo sapiens
Sequence 2:NP_594820.1 Gene:alp7 / 2543382 PomBaseID:SPAC890.02c Length:474 Species:Schizosaccharomyces pombe


Alignment Length:317 Identity:64/317 - (20%)
Similarity:110/317 - (34%) Gaps:97/317 - (30%)


- Green bases have known domain annotations that are detailed below.


Human  1584 IPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATE 1648
            ||..|.|.|..:...||..|.        :..|.||.|...|...||..:..:......||...:
pombe   213 IPTQYPINSTQKQQAKYEAEI--------EGYKAKLAGTYHEISVLQNTIVNVSGQLIAVNDQLQ 269

Human  1649 RIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQ 1713
            ::.......:.:.:...|.:.|...:.||                           .:|...:||
pombe   270 QLRSGKASTSPSTKDTNMRLVEGHNEETL---------------------------ALQRGKYTQ 307

Human  1714 LHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEA-LVREAEAKMQE 1777
                        |::...|||..:|..|:|.....|      ||..::.|.:| ..|:.||.:||
pombe   308 ------------EEVDKLIQERMEKVAEDLHAQYSA------KHTQKINAFKANYARKYEATIQE 354

Human  1778 SNHLL-------LMVNANLRE----------FSDKKLH--VQEEQNL-------------TSELI 1810
            ..:.:       .:.|:|..|          ...|:|.  :||.|::             :.:|:
pombe   355 LQNQIGTAPNAPKISNSNWEEERRALKADNQTLQKQLEKAIQERQDMSDFLNNFKADMAKSDKLL 419

Human  1811 VQGR----GLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRN 1863
            :|.:    |.::....|..|:|:.|....:.:.:|:..|       :|||:.|.|.|
pombe   420 MQQQSQQTGDLETLRLQLQALQEELRVEREERQQLIQMS-------EDLVIAMDQLN 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LAMA1NP_005550.2 LamNT 16..268 CDD:214532
EGF_Lam 270..317 CDD:238012
Laminin_EGF 397..456 CDD:278482
Laminin_EGF 454..500 CDD:278482
Laminin_B 568..696 CDD:278481
EGF_Lam 741..789 CDD:238012
Laminin_EGF 791..846 CDD:278482
EGF_Lam 848..900 CDD:238012
Laminin_EGF 902..948 CDD:278482
Laminin_EGF 951..998 CDD:278482
Laminin_EGF 998..1041 CDD:278482
Laminin_EGF 1044..1092 CDD:278482
Laminin_EGF 1090..1147 CDD:278482
LamB 1213..1344 CDD:214597
Laminin_EGF 1403..1449 CDD:278482
Laminin_EGF 1452..1506 CDD:278482
Laminin_EGF 1509..1556 CDD:278482
Laminin_I 1567..1830 CDD:283627 55/282 (20%)
BAR 1609..1841 CDD:299863 48/268 (18%)
Laminin_II 2011..2145 CDD:283628
LamG 2141..2280 CDD:214598
LamG 2307..2463 CDD:238058
Laminin_G_1 2514..2658 CDD:278483
Laminin_G_1 2743..2872 CDD:278483
LamG 2892..3043 CDD:238058
alp7NP_594820.1 Kinetocho_Slk19 316..407 CDD:289479 22/96 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100395
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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