Protein Alignment SLC13A5 and slc13a5a

DIOPT Version :10

• Sequence 1: NP_808218.1
• Gene: SLC13A5 / 284111
• HGNCID: 23089
• Length: 568
• Species: Homo sapiens
• Sequence 2: XP_005161489.1
• Gene: slc13a5a / 503788
• ZFINID: ZDB-GENE-030131-4628
• Length: 582
• Species: Danio rerio
• Alignment Length: 584
• Identity: 359/584 - (61%)
• Similarity: 459/584 - (78%)
• Gaps: 21/584 - (3%)

Human     1 MAS-ALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPV 64
            ||| ||..|.|.|:.:|||.||.|||||.:::.:|...||||::|||:||||||:|||||:|:|.
Zfish     2 MASRALKLVWKMKNTLILFCTPFLLLPLPLVIGSKEAGCAYVVVLMAVYWCTEVLPLAVTALLPA 66

Human    65 LLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFM 129
            :|||||:|::|:.||:||:|||||||||||:||||||.||||||||||.||.||.:||.||||||
Zfish    67 VLFPLFRIMESKDVCMQYLKDTNMLFLGGLMVAVAVEHWNLHKRIALRVLLLVGVRPALLMLGFM 131

Human   130 GVTALLSMWISNTATTAMMVPIVEAILQQMEATSAATEAGL-ELVDKG--KAKELPGSQ-VIFEG 190
            ||||.||||||||||||||||||:|:|:|:..|:...::.: |..:|.  |..|.||.: |:..|
Zfish   132 GVTAFLSMWISNTATTAMMVPIVQAVLEQLNNTAQQEQSSIPETEEKSTEKQPESPGEEKVVLNG 196

Human   191 PTLGQQED--------QERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDL 247
            .....:.|        :||.::.|.:|||:||||||||||||||||||:||:|||::||||:.|:
Zfish   197 DNFSMESDPEEHSREAEERLKMSKGLTLCVCYAASIGGTATLTGTGPNLVLMGQMSQLFPDNPDI 261

Human   248 VNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPL 312
            :||||||.||||||::||..||||||.|::..||||:||||....:.|.||..|::||:|.|||:
Zfish   262 INFASWFGFAFPNMIIMLTLAWLWLQIVFLGINFKKTWGCGTVKTEKEIAAYNVIKEEHRSLGPM 326

Human   313 SFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKF 377
            :|.|::||..|.|||:|||:|||||:.||.| .:...:.::|:|||||:|||.|||:.||:.|:.
Zfish   327 TFGELSVLALFILLVVLWFTRDPGFVDGWAT-RFFNADKEFVTDATVAVFVAALLFVFPSKPPRL 390

Human   378 NF-RSQT----EEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQM 437
            .| |:::    .::...|  .|.||.|||||:|:||.|:||||||||||||||.||||.|:|.||
Zfish   391 CFWRTESFDTVPQQESGP--TPALLTWKVTQKKMPWSIILLLGGGFALAKGSEISGLSKWLGDQM 453

Human   438 EPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAF 502
            .||.::||.||.:::.|::|.||||||||||.||||||.||||:|||:||||:|:||||||||||
Zfish   454 SPLQSIPPWAIAIVICLMIATFTECTSNVATATLFLPILASMSQSIGVNPLYVMVPCTLSASFAF 518

Human   503 MLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHI 566
            |||||||||||||:||:|||:||.|||::|||||:..:.||:|:||||||.||.||.|||.|.:
Zfish   519 MLPVATPPNAIVFSYGYLKVSDMAKTGIVMNIIGILSITLAINSWGRAIFSLDTFPSWANTTDV 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC13A5	NP_808218.1	CitMHS	<11..164	CDD:460985	108/152 (71%)
		CitT	91..547	CDD:440239	288/472 (61%)
slc13a5a	XP_005161489.1	ArsB_NhaD_permease	35..570	CDD:473875	333/537 (62%)