Protein Alignment SLC13A5 and CG33934

DIOPT Version :10

• Sequence 1: NP_808218.1
• Gene: SLC13A5 / 284111
• HGNCID: 23089
• Length: 568
• Species: Homo sapiens
• Sequence 2: NP_001163660.1
• Gene: CG33934 / 3772159
• FlyBaseID: FBgn0064119
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 199/562 - (35%)
• Similarity: 298/562 - (53%)
• Gaps: 58/562 - (10%)

Human    21 PLLLLPLVI---LMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQY 82
            ||:.||::|   |......:|.|::..||::|.||.|||.:|:|.||:..|||.||.|.:||..|
  Fly    31 PLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILTSEKVCSFY 95

Human    83 MKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAM 147
            ..||.::|:|||::|:|:|..|||:||||.|:|.||..|.||..|.:.||..:|:||||:|.|||
  Fly    96 FSDTVVMFIGGLLIALAIEYSNLHQRIALNTILIVGCSPRRLHFGLVMVTCFISLWISNSAATAM 160

Human   148 MVPIVEAILQQMEATSAATEAGLELVDKGKAKELPGSQVIFEGPTLGQQEDQER------KRLCK 206
            |.|||:|:|.:||                       :|.||......::|..|.      ..:..
  Fly   161 MCPIVKAVLNEME-----------------------TQNIFAIYKTQEEEPVEEGDPPHPSTISM 202

Human   207 AMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLF-AWL 270
            |....|.|::||||..||.|||.|:...|..:..||:|.:.::|..:.|::.|.::::|:| .:.
  Fly   203 AFYFGIAYSSSIGGCGTLIGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVLVLIFLTYF 267

Human   271 WLQFVYMRFNFKKSWGCGLESKK---NEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFS 332
            .||..:|.. |:.:...|.|.||   ::.....|:::...:|||:|..||.|.:.|.|::.|.|:
  Fly   268 SLQVTHMGL-FRPNSKIGQEVKKGAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFT 331

Human   333 RDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLL 397
            |.|||.|||....    ..|.:.......|...|||.:|:|...|.:..     .|.|| |...|
  Fly   332 RKPGFFPGWADFL----NAKAIGSGPPVFFATILLFALPTQYTFFKYCC-----GKAPF-PGQTL 386

Human   398 D----WKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQME---PLHAVPPAAITLILSLL 455
            |    |...|:..|:|:..|||||||||:||..||::..:|:.:.   .:|:|...::.:|:||.
  Fly   387 DACLSWVYCQKYTPFGLAFLLGGGFALAEGSRVSGMAKMLGESLAFAGEMHSVLVISMCIIISLF 451

Human   456 VAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHL 520
            ...|   .||||...:.:|||:.|:.:|.::|:.:..|..|:.|.||.|||:||||||:..:..|
  Fly   452 CTAF---ASNVAICNILIPIFSEMALAIEVHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGL 513

Human   521 KVADMVKTGVIMNIIGVFCVFLAVNTWGRAIF-DLDHFPDWA 561
            |...|...|::.......|:......|...|: ....||.||
  Fly   514 KTKYMAIAGILPTCWAFLCLLFTGTVWTMLIYPGTTEFPSWA 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC13A5	NP_808218.1	CitMHS	<11..164	CDD:460985	72/145 (50%)
		CitT	91..547	CDD:440239	161/472 (34%)
CG33934	NP_001163660.1	ArsB_NhaD_permease	<32..165	CDD:473875	65/132 (49%)
		CitT	104..540	CDD:440239	161/472 (34%)