Protein Alignment SLC13A5 and nac-1

DIOPT Version :10

• Sequence 1: NP_808218.1
• Gene: SLC13A5 / 284111
• HGNCID: 23089
• Length: 568
• Species: Homo sapiens
• Sequence 2: NP_510473.2
• Gene: nac-1 / 181585
• WormBaseID: WBGene00003517
• Length: 582
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 241/613 - (39%)
• Similarity: 343/613 - (55%)
• Gaps: 88/613 - (14%)

Human     3 SALSYVSKFKSFVI----LFVTPLLLLPLVILMPAKFV--------RCAYVIILMAIYWCTEVIP 55
            |:|..:.| :||||    |..:|||:          ||        :|.|.:.:|..||..|.:|
 Worm     8 SSLLLIYK-QSFVIWGALLIFSPLLM----------FVGDSHGLQAKCLYCVAVMGSYWVFEALP 61

Human    56 LAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAK 120
            ||:|:.:|::|||||.|:.|.:|...|:.||..||:|||:||:|||:..||.|:||..|..||::
 Worm    62 LAITAFIPMILFPLFGIMRSEEVARAYLPDTCFLFMGGLMVALAVEKCELHARVALFVLKTVGSE 126

Human   121 PARLMLGFMGVTALLSMWISNTATTAMMVPIVEAIL------QQMEATSAATEA----------G 169
            |||:|.||||||..||||||||||||:||||:::::      .:||...|..||          |
 Worm   127 PARVMAGFMGVTGFLSMWISNTATTALMVPILQSVITELVSNHRMEDLVALCEAHHNSSRKHSVG 191

Human   170 LELVDKGKAKELPGSQVIFEGPTLGQQEDQERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLL 234
            :      :...||......:...:........:::.|.:.|.:|::|:|||.||:|||..|:||:
 Worm   192 M------RRLSLPNENNEIKREEMDTAMSPREQKMAKGLMLSVCFSANIGGAATITGTASNLVLV 250

Human   235 GQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKNEKAAL 299
            ||:|||||.:...|||.||..||||.:...|::.|..|..:|:|           ::.|......
 Worm   251 GQLNELFPGADTGVNFLSWLIFAFPMVFCCLIYCWCVLYLLYLR-----------DAPKGSIIVT 304

Human   300 KVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGE---TKYVSDATVAI 361
            :.||::|.:|...||||:.|:.||.||::||..|:|..:|||       ||   .::|||||.|:
 Worm   305 RKLQQKYNELHAFSFAEMAVIFCFALLLVLWILREPQVVPGW-------GEMFKDEFVSDATSAM 362

Human   362 FVATLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEA 426
            |:..|||.:|.:.|.....|   |:||.   ...||||...|::.||.::.|||||||||.|.:.
 Worm   363 FIVILLFTLPEKLPSSRGSS---EQRKA---SSGLLDWATVQDRFPWSVLFLLGGGFALAAGVKE 421

Human   427 SGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIM 491
            ||||..:|..|..|.......|.||..::....|...||....::|:||.|.::||:.::||..|
 Worm   422 SGLSHDIGAIMRYLDVFNHNIIMLICIIISVTLTNVCSNTVIASIFIPIVAELARSLEIDPLNFM 486

Human   492 LPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDH 556
            ||.|:||||||:||||||||||||:.|:|||.||..:|:.:.:..|....|.:..|...:|:|..
 Worm   487 LPVTISASFAFLLPVATPPNAIVFSSGYLKVFDMFVSGLCVTLGCVVLSMLNMLLWAGFVFNLHL 551

Human   557 FPDWA----------------NVTHIET 568
            ||.||                |:|.:.|
 Worm   552 FPQWAANPSPPLDVQDWAVENNITFVGT 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC13A5	NP_808218.1	CitMHS	<11..164	CDD:460985	78/170 (46%)
		CitT	91..547	CDD:440239	194/474 (41%)
nac-1	NP_510473.2	CitT	97..545	CDD:440239	195/477 (41%)