Protein Alignment GPR17 and AstC-R1

DIOPT Version :9

• Sequence 1: NP_001154887.1
• Gene: GPR17 / 2840
• HGNCID: 4471
• Length: 367
• Species: Homo sapiens
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 92/365 - (25%)
• Similarity: 168/365 - (46%)
• Gaps: 44/365 - (12%)

Human    20 LSGSDSSQSMNGLEVAPPGLITNFSLATAEQC-GQETPLENMLFASFYLLDFILALVGNTLALWL 83
            :|||.:.|        |...:....|.|.:.| .......::.....|....|:.|.||||.:::
  Fly    45 ISGSSTIQ--------PEESLYGTDLPTYQHCIATRNSFADLFTVVLYGFVCIIGLFGNTLVIYV 101

Human    84 FIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIY 148
            .:|..|..|..|:::::||||| .|.|:....|:|......|.|||..|:.......:..:.|..
  Fly   102 VLRFSKMQTVTNIYILNLAVAD-ECFLIGIPFLLYTMRICSWRFGEFMCKAYMVSTSITSFTSSI 165

Human   149 FLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTV--VCLQ 211
            ||..:||||::|:.||:.|.:.|....|.:..|..|...||.|.|:::...||:....:  .|..
  Fly   166 FLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDGINYSCNI 230

Human   212 LYREKASHHA-----LVSLAVAFTFPFITTVTCYLLIIRSLRQ-------GLRVEKRLKTKAVRM 264
            ::.:....|:     |.:..:.|..|....::.|.|:||.||.       ..:.::|...|..|:
  Fly   231 MWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRL 295

Human   265 IAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVA 329
            :..|::::::|::|:.::: |.::|  |:.|.....|:..|...:...|...|.|::||:|.|::
  Fly   296 VLTVISVYILCWLPHWISQ-VALIH--SNPAQRDLSRLEILIFLLLGALVYSNSAVNPILYAFLS 357

Human   330 EKFRHALCNLLCGKRLKGPPPSFEGKT--NESSLSAKSEL 367
            |.||.:.               |:..|  |:..::|:.:|
  Fly   358 ENFRKSF---------------FKAFTCMNKQDINAQLQL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPR17	NP_001154887.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		3/7 (43%)
		7tm_1	76..325	CDD:278431	71/262 (27%)
AstC-R1	NP_649040.2	7tm_4	88..368	CDD:304433	79/298 (27%)
		7tm_1	94..353	CDD:278431	71/262 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910