Protein Alignment SLC24A5 and Nckx30C

DIOPT Version :10

• Sequence 1: XP_047288350.1
• Gene: SLC24A5 / 283652
• HGNCID: 20611
• Length: 531
• Species: Homo sapiens
• Sequence 2: NP_652011.3
• Gene: Nckx30C / 45248
• FlyBaseID: FBgn0028704
• Length: 881
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 180/593 - (30%)
• Similarity: 278/593 - (46%)
• Gaps: 158/593 - (26%)

Human    54 FPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTFMAAGS 118
            ||:..||:::..:|.:|::.:.::|||:|::|||||:|:|||::|.|.||::.||||.||||||.
  Fly   318 FPKDLFTKEQLENGAVILHIIGVIYMFVALAIVCDEFFVPSLDVIIEKLGITDDVAGATFMAAGG 382

Human   119 SAPELVTAFLGKYCSLYFLLTQCDFYFLQVNTNLAGTILHIGVFITKGDIGISTILGSAIYNLLG 183
            |||||.|:.                               ||||::..|:||.||:|||::|:|.
  Fly   383 SAPELFTSV-------------------------------IGVFVSFDDVGIGTIVGSAVFNILF 416

Human   184 ICAACGLLSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFD 248
            :...|.|.|.||.:|:.|||||||:.|:||...::....||:::|:|..:|..||..||..:.::
  Fly   417 VIGMCALFSKTVLSLTWWPLFRDCSFYSISLLVLIYFFRDNRIFWWEALILFTIYIGYVAFMKWN 481

Human   249 IKINQYIIKKCSPCCACLAKAMER--------SEQQPLMGWEDEGQPFIRRQSRTDSGIFYED-- 303
            :::...:.|..:.......::.::        :..:..|..:..|....|..|.|.||.....
  Fly   482 VQVETCVKKMITKNKVTRVRSTDQLMPAGNAANSSETSMATQPGGSVTSRAASETRSGPPGSSNA 546

Human   304 ------------SGYSQLSISL-HGLSQVS----------------------------------- 320
                        ||.:|..... |||.|:.
  Fly   547 GATGNSSGGGGTSGSTQTGAKFRHGLLQLMIHTIDPLHDGKVDEKATQLHAIASLKVLLDATKPQ 611

Human   321 ----------------------------------------------------------------E 321
                                                                            |
  Fly   612 RGGATTSAANHVKINLKETTLADRPNGNIDTTLDSPSLSGRRPSWIEQRVKIQTRKFSIKAPEIE 676

Human   322 DPPSVFNM--PEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILV 384
            |.|...:|  |:...||:.:||..|::..::||.||.|....|.:|.:||..|.:||:||:|::|
  Fly   677 DEPEPLSMAWPDTARKRLTYVLVAPLLVPMWLTLPDTRTPRGKRFFPVTFIGSIVWIAAFSYLMV 741

Human   385 WMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDM-LCLGIP 448
            |...:.|:|..||..|||||.|||||||||.|.||:|||||.||||:|:.||||:||: :.|.||
  Fly   742 WWANVAGDTARIPPEVMGLTFLAAGTSIPDLITSVIVARKGFGDMAVSSSVGSNIFDVTVGLPIP 806

Human   449 WFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGLATLS 513
            |.: ...|.| ||.||||.|:......|.:.::|:.:::....|::::.||....|.|.....:|
  Fly   807 WLL-YGIIYG-APVEVNSVGMVCSITILFMMLVFVVMSIACFRWRMNKGLGFTMFLLYFAFVAVS 869

Human   514 VLYELGII 521
            :::|..:|
  Fly   870 LMFEYDVI 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC24A5	XP_047288350.1	2A1904	<20..>255	CDD:273344	78/200 (39%)
		2A1904	<321..521	CDD:273344	86/202 (43%)
Nckx30C	NP_652011.3	2A1904	<318..880	CDD:273344	180/593 (30%)