Protein Alignment TSSK4 and KP78b

DIOPT Version :10

• Sequence 1: NP_001171668.1
• Gene: TSSK4 / 283629
• HGNCID: 19825
• Length: 338
• Species: Homo sapiens
• Sequence 2: NP_650065.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 110/327 - (33%)
• Similarity: 167/327 - (51%)
• Gaps: 42/327 - (12%)

Human    23 YG-YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLI 86
            || |::.|.:|.|::..|..|.:......||:|:|. |.|.:....:.|.||:.:||.|.|..::
  Fly    60 YGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLID-KTALNTIARQKLYREVNIMKKLNHPNIV 123

Human    87 NFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPS 151
            ...:.|||...:|:::|...||::..::.:.|...|..|...|.||...|.|.|||||||
  Fly   124 RLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVH----- 183

Human   152 LSAAGRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYAC 216
                 ||||.||||||:...:||:||||:.......|:                :|:|||..||.
  Fly   184 -----RDLKAENLLLDQQMKLKIADFGFSTTFEPKAPL----------------ETFCGSPPYAA 227

Human   217 PEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLI 281
            ||:.||..|:....|:||:||:|||||...||||.||||: ||:......:...:.:|.||::||
  Fly   228 PELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKE-LRDRVLRGKYRVPYYVSIECESLI 291

Human   282 LQML-RQATKRATILDIIKDSWV---------LKFQPEQP--THEIRLLEAMCQL-HNTTKQHQS 333
            .:.| ...|:|.::..::.|.|:         |:...|:|  .|::..|..:..: |......||
  Fly   292 RKFLVLNPTQRTSLSAVMADRWINMGYEQGNGLRPFQEKPMDLHDVNRLSLLSNMGHKPRDVEQS 356

Human   334 LQ 335
            |:
  Fly   357 LK 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSSK4	NP_001171668.1	STKc_TSSK4-like	24..303	CDD:271064	99/280 (35%)
KP78b	NP_650065.1	Protein Kinases, catalytic domain	63..314	CDD:473864	98/278 (35%)
		UBA_MARK_Par1	335..373	CDD:270522	6/24 (25%)