Protein Alignment TSSK4 and par-1

DIOPT Version :10

• Sequence 1: NP_001171668.1
• Gene: TSSK4 / 283629
• HGNCID: 19825
• Length: 338
• Species: Homo sapiens
• Sequence 2: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 323
• Identity: 107/323 - (33%)
• Similarity: 169/323 - (52%)
• Gaps: 42/323 - (13%)

Human    25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFY 89
            |::.|.||.|::..|..|.:......||:|||.|.:.:...|.| |.||:::||:|.|..::..:
  Fly   253 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQK-LFREVRIMKMLDHPNIVKLF 316

Human    90 RAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSA 154
            :.||:...:|:|:|.|.||:|.:::..:|...|..|...|.|:...:.|.|.|.|:|
  Fly   317 QVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIH-------- 373

Human   155 AGRDLKLENLLLDKWENVKISDFGFA-KMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPE 218
              ||||.||||||...|:||:||||: :..|.::                 ..|:|||..||.||
  Fly   374 --RDLKAENLLLDSELNIKIADFGFSNEFTPGSK-----------------LDTFCGSPPYAAPE 419

Human   219 ILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQ 283
            :.:|..|:....|.||:||||||||...||||.:.|:: |||......:.....:|.:|:||:.:
  Fly   420 LFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRE-LRERVLRGKYRIPFYMSTDCENLLRK 483

Human   284 ML-RQATKRATILDIIKDSWV--------LK--FQPEQPTHEIRLLEAMCQL-HNTTKQHQSL 334
            .| ....|||::..|:.|.|:        ||  .:|:....:.:.:||:..: :|.::...||
  Fly   484 FLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSSK4	NP_001171668.1	STKc_TSSK4-like	24..303	CDD:271064	98/279 (35%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	98/279 (35%)
		UBA_MARK_Par1	525..563	CDD:270522	5/22 (23%)
		MARK1-3_C	839..936	CDD:213381