Protein Alignment GXYLT1 and CG11149

DIOPT Version :10

• Sequence 1: NP_775872.1
• Gene: GXYLT1 / 283464
• HGNCID: 27482
• Length: 440
• Species: Homo sapiens
• Sequence 2: NP_608952.2
• Gene: CG11149 / 33800
• FlyBaseID: FBgn0031732
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 95/545 - (17%)
• Similarity: 170/545 - (31%)
• Gaps: 197/545 - (36%)

Human     2 RRYLRVVVLCVACGFCSLL-YAFSQLAVSLEEGTGGGGGKPQAAVASWLAGGGRGAVRGAGVAGP 65
            |:|:|:..:.:......|| :...|.|..|...:..||.|....:.|             ..:.|
  Fly     9 RKYVRLWPVLILFNVALLLVWRNLQQAQKLAASSNTGGQKSVGLLLS-------------NESNP 60

Human    66 A-----------AHPGVSDR--------------CKDFSLCY----WNPYWMLPSDVCGMNCFWE 101
            :           .||.:..|              |:|.||.:    ...:|:|.:.|.|
  Fly    61 SRFSANFHLANDQHPKIIRREDSARTKELRSLLKCRDRSLRFERLQHGEFWLLQNLVMG------ 119

Human   102 AAFRYSLKIQPVEKMHLAVVACGE--------------RLEETMTMLKSAIIFSIKPLQFHI--- 149
               |.|.:           |.|.|              .||..::..::.:.|:|....:.:
  Fly   120 ---RKSRE-----------VGCAESVTYTTNGDFTFFDNLEMVVSRWRAPVSFAIHTPGYDLNTT 170

Human   150 -----FAEDQLHHSFKGRLDNWSFLQTFNYTLYPITFPSENAAEW------KKLFKP--C--ASQ 199
                 :..:.|..|  ..:.:|        ..:.:.||:::..|:      :.|..|  |  |:.
  Fly   171 LDAIRYVRNCLPES--DSIKDW--------VSFHVYFPNQHMPEYVPYDEAEVLMYPHMCTLANG 225

Human   200 RLFLPLI--LKEVDS------LLYVDTDILFLRPVDDIWSLLKKFNSTQIAAMAPEHEEPRIGWY 256
            .|..||.  :...||      |.|         |::...::.:...:|...........|.:|:.
  Fly   226 SLVSPLYTQIPTTDSYKSRANLTY---------PINVGRNIARLATNTHFIFACDIELYPSVGFV 281

Human   257 NRF----ARHPYYGKTGVNSGVMLMNMTRMRRKYFKNDMTTVRLQWG-------DILMPLLKKYK 310
            ::|    ||         |..|:.::..:.||.|   .:....::.|       |.|:.|.:|.:
  Fly   282 DQFLDMVAR---------NHSVLALDPRQRRRVY---PLPVFEIETGAKVPVDKDELLALYRKQQ 334

Human   311 LNITW-----------GDQDLLNIVFFHNPESLFVFP---CQWNYRPDHCIYGSNCQEAEEGGIF 361
            ..:..           |.::.||.. ....:.|.||.   .:|.:|.....|.|
  Fly   335 AQVFHLKLCPTCHTIPGQEEWLNRT-SRADDHLHVFSKALRKWKFRAWEPFYVS----------- 387

Human   362 ILHGNRGVYHDDKQPAF--RAVYEALRNCSFEDDNIRSLLKPLELELQKTVHTYCGKIYKIF--- 421
                      |:.:|.|  |..:|...|...:.....|.:...:..|....:..|...|:..
  Fly   388 ----------DNTEPLFDERVTWEGQSNKRIQVSYYCSQVSVSQCNLLLQNYAMCLLDYEYHVLS 442

Human   422 ---------IKQLAK--SVRDRYAR 435
                     |||.:|  |.|.:||:
  Fly   443 PAFLVHSPGIKQSSKADSTRLQYAK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GXYLT1	NP_775872.1	GT8_like_2	116..417	CDD:133052	60/367 (16%)
CG11149	NP_608952.2	Glyco_transf_49	130..486	CDD:464027	66/391 (17%)