Protein Alignment MYO1H and myo1h

DIOPT Version :9

• Sequence 1: XP_011536525.1
• Gene: MYO1H / 283446
• HGNCID: 13879
• Length: 1044
• Species: Homo sapiens
• Sequence 2: XP_017945451.1
• Gene: myo1h / 100492763
• XenbaseID: XB-GENE-963784
• Length: 1036
• Species: Xenopus tropicalis
• Alignment Length: 1044
• Identity: 722/1044 - (69%)
• Similarity: 858/1044 - (82%)
• Gaps: 23/1044 - (2%)

Human     1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQ 65
            |||:|:||||||||||||||::|||:||:|||||||.||||||||||:||||||||||.:||..|
 Frog    16 MEGSLSARDKVGVQDFVLLDSHTSEAAFMDNLRKRFQENLIYTYIGTMLVSVNPYQELQLYTQRQ 80

Human    66 MELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130
            |||||||||.|||||:||:||||||:||.|.||||||||||||:||||.|||||:|.|:|||:|:
 Frog    81 MELYQGVNFIELPPHIYAVADNAYRVMCTERNNHFILISGESGSGKTETSKKILQYLAMTCPVTE 145

Human   131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQ 195
            .||..|||||.|||||||||||:|:|||||||||||||:|||::|.|.||||:||||||||||:|
 Frog   146 KLQTIRDRLLLSNPVLEAFGNAKTIRNDNSSRFGKYMDVQFDYKGAPAGGHILSYLIEKSRVVHQ 210

Human   196 NEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFSVID 260
            |.||||||||||||.|||:..:.:|||||:||:|.||.||.|||.|||.||.:||.|..||::|:
 Frog   211 NPGERNFHIFYQLLEGGEDHLIRWLGLERNPQMYSYLIQGECAKVSSICDKTNWKLVRRAFTIIE 275

Human   261 FTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHPSVLLEALTHRKIEA 325
            |||||:|:||||:|||||||||.:|||..|.|.|.:..:::||:|||||..|:|.||||::||||
 Frog   276 FTEADIEHLFGIVASVLHLGNIKYEEDTHGHAIIRNGSQMQWISKLLGVPVSILQEALTNKKIEA 340

Human   326 KTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTVIGLLDIYGFEVFDK 390
            ::|||:.||.|||:.|||||:|||:|||:|.||||||||||.|||..:|||||||||||||||:.
 Frog   341 RSEEVLSPLNLELAYYARDALAKAIYGRSFNWLVNKINSSLANKDPPKKTVIGLLDIYGFEVFET 405

Human   391 NGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILD 455
            |.||||||||||||||||.|..||||||.|||:|||||||::||:|||||||:||::||||:|:|
 Frog   406 NSFEQFCINYCNEKLQQLFISMTLKAEQEEYEIEGIEWEPVQYFDNKIICDLIEEKYKGIIAIMD 470

Human   456 EECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLE 520
            |||:|||.|||||||.|||||||.|.||.|||||.|..||.|.|::|||:|||||||||..||||
 Frog   471 EECLRPGEATDLSFLAKLEEKVGDHPHFLTRKLADPVARKTIDWVDFRLIHYAGEVTYCAVGFLE 535

Human   521 KNNDLLYRHLKEVLCKSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRC 585
            ||||||||:||||:.||||.|||:||...||:|||||.||.||||||||||:|.|:.|||:||||
 Frog   536 KNNDLLYRNLKEVVLKSKNYILRDCFHPTELDNRRRPETVTTQFKNSLSSLIEILLLKEPTYIRC 600

Human   586 IKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYLGVELSHWVERLMMS 650
            ||||:.|:|.||:|.|:|||:|||||||||||||||||||||||.||
 Frog   601 IKPNNTKQPGKFEDMLVRHQVKYLGLMEHLRVRRAGFAYRRKYEIFL------------------ 647

Human   651 LFYKDRYKSLCPDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFS 715
                :|||||||.|||:|.||..||||:|:||:||:|.|||||:||:|||||||||||.|:||..
 Frog   648 ----ERYKSLCPQTWPNWAGPAREGVEKLVKYLGYQPNEYKLGRTKLFIRFPRTLFATVDSFEIR 708

Human   716 KHQLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRN 780
            |||||::|||.||.|||:|.:.||::||||||:.|||.|||:..::|.|||:.|||||.|||:|.
 Frog   709 KHQLVSKIQAKYKGCLGKRAFEKKKKAAIKLESCWRGVLARREAKKRAWAVQTIRKFIVGFINRK 773

Human   781 KPLCPDNEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGI 845
            .|....|:.|...:..||:..||.|:||.||||.||.||..:|..|:||.|:|:||||:||||.|
 Frog   774 NPDADTNKNFFGMMYYNYLWKLREHVPKNVLDKRWLTPPVAMEKTSELLHKLCIRNLVRKYCRTI 838

Human   846 TAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKY 910
            |.:|...:|||||||:||:|:|:||.:||.|||..:|:.|.|||||||||:::::|:||:..:||
 Frog   839 TPQRTHQLQQKVVTSQIFKGKKEGYKQSLCQPFEETRLSEQDINPKVLQLMNYDRIKYGIAAVKY 903

Human   911 DRKGFKARQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAV 975
            ||.|||||.|||:|||.||||.|.||||||||||.|||:|.|||:||.|:|||||||:||||||:
 Frog   904 DRHGFKARPRQLLLTQSAAYVTEQAKIKQKIEYSGLKGISVSNLNDGFLIIHVSPEDNKQKGDAI 968

Human   976 LQCGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSV 1040
            |||.|:|||||||.||..|::.|.:.||||.|... ||||.|.|..|.|.||||.|||.|||.:.
 Frog   969 LQCDHIFEAVTKLCMLASKQDAVTIAQGSLTFHFQ-GKEGIIDFTHGAEAQVYKAKNGHLTVATP 1032

Human  1041 RRKS 1044
            |.||
 Frog  1033 RLKS 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYO1H	XP_011536525.1	MYSc	8..711	CDD:214580	512/702 (73%)
		MYSc_Myo1	26..700	CDD:276829	486/673 (72%)
		Myosin_TH1	856..1019	CDD:283635	108/162 (67%)
myo1h	XP_017945451.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1041	1.000	Domainoid score	I586
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H82639
Inparanoid	1	1.050	1492	1.000	Inparanoid score	I1415
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105718at33208
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	1	1.000	-	-		oto148157
Panther	1	1.100	-	-	LDO	PTHR13140
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8013
SonicParanoid	1	1.000	-	-		X2957
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.190