Protein Alignment SLC22A24 and CG33233

DIOPT Version :9

• Sequence 1: NP_001129978.2
• Gene: SLC22A24 / 283238
• HGNCID: 28542
• Length: 552
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 474
• Identity: 92/474 - (19%)
• Similarity: 174/474 - (36%)
• Gaps: 126/474 - (26%)

Human   139 CE---SQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPTFLVYC 200
            ||   |...|:::.:..:.|.:..||..|.|:||.|||.:.:|..:.....:..:|..|......
  Fly    49 CEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLS 113

Human   201 ILRFLAG--FSTMTILGNTFI---LSLEWTLPRSRSMTIMVLLCSYSVGQMLLG----------- 249
            ::|.:.|  .|.:..|...|:   .:::|       ..|.|.:||.|.|..|:.
  Fly   114 VIRIIVGTFLSAVASLQVGFLGEFHAIKW-------RPITVAICSQSQGLALIYCPLVAMAILPN 171

Human   250 ------GLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGK 308
                  ..::.::.|..|.:....|..:..:....:.|:..:|:..|:.|:.|..|:.:..:|.|
  Fly   172 NFNVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRK 236

Human   309 KNTEETLTTELVRS----------TMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVP 363
            |..:..:|....:|          |:..|...:..|..:|..|....|   :||:.|....:.:
  Fly   237 KWEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFL---IFGIFFTSIGLGI- 297

Human   364 FYGLILNLQHLGSNVSLFQILCGAV----TFTARCVSLLTLNH------------------MGRR 406
            ::.:|.|:.:.|||     .||..|    ||         :||                  |...
  Fly   298 WFPVIRNMDNSGSN-----RLCDLVNNNPTF---------INHEADDTNGTDSESPKCNDEMTNL 348

Human   407 ISQILFTFP-VGLFILVNTFL----------------------------PQEMQILRVVLATLGI 442
            |..:.:.|. :|.|||.:..:                            |..:.|..|::..|.
  Fly   349 IDPVYYGFTYIGCFILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFFVLMMVLP- 412

Human   443 GSVSAASNSASVHHNELVPTILRS----TVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGV 503
            |.:...:.|..|   :.:|..||.    .|..:....|..|:.:..|.:.:...      :::.:
  Fly   413 GVLIPLATSVLV---DCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCD------VTFNI 468

Human   504 FPI-LAVPVILLLPETRDL 521
            |.: ||:.|:|.:.:.:|:
  Fly   469 FNLCLAICVVLAVFQPKDI 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A24	NP_001129978.2	MFS_OAT	109..516	CDD:340932	91/467 (19%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	84/430 (20%)
		MFS	23..>208	CDD:119392	33/165 (20%)
		MFS	354..>482	CDD:304372	24/137 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840