Protein Alignment NPBWR2 and Npbwr1

DIOPT Version :10

• Sequence 1: NP_005277.2
• Gene: NPBWR2 / 2832
• HGNCID: 4530
• Length: 333
• Species: Homo sapiens
• Sequence 2: NP_001014784.1
• Gene: Npbwr1 / 297795
• RGDID: 1305917
• Length: 329
• Species: Rattus norvegicus
• Alignment Length: 331
• Identity: 202/331 - (61%)
• Similarity: 247/331 - (74%)
• Gaps: 17/331 - (5%)

Human     8 EPLDSRGSFSL--PTMGANVSQDNGTGHNATFSEPLPF---LYVLLPAVYSGICAVGLTGNTAVI 67
            ||  .||:.|.  |.:|.         .|.:...|||.   |.|.:|.||..||||||.||:||:
  Rat     8 EP--GRGNVSCGGPFLGC---------PNESNPAPLPLPQPLAVAVPVVYGVICAVGLAGNSAVL 61

Human    68 LVILRAPKMKTVTNVFILNLAVADGLFTLVLPVNIAEHLLQYWPFGELLCKLVLAVDHYNIFSSI 132
            .|:||.|:|||||||||||||:||.|||||||:|||:.||:.|||||::|||::|||.||.|||:
  Rat    62 YVLLRTPRMKTVTNVFILNLAIADELFTLVLPINIADFLLRRWPFGEVMCKLIVAVDQYNTFSSL 126

Human   133 YFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLPFFSFAGVYSNELQVPSC 197
            |||||||.|||||||||..||.:..|||..|:..||.||..||::||||..||.: ..|.....|
  Rat   127 YFLAVMSADRYLVVLATAESRRVSGRTYGAARAVSLAVWALVTLVVLPFAVFARL-DEEQGRRQC 190

Human   198 GLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRLRAVRLRSGAKALGKARRKVTVLV 262
            .|.||.||..|::|||:|||||||.:||.|||.||..||.||||::|.|.||||.:|:::||:||
  Rat   191 VLVFPQPEAFWWRASRLYTLVLGFAIPVSTICALYITLLCRLRAIQLDSHAKALDRAKKRVTLLV 255

Human   263 LVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISMSYVITSLSYANSCLNPFLYAFLDDNFRKNF 327
            :.:||||||||||:||:::||||||||||||||.:||.|||||||||||||||||||||:||::.
  Rat   256 VAILAVCLLCWTPYHLSTIVALTTDLPQTPLVIGISYFITSLSYANSCLNPFLYAFLDDSFRRSL 320

Human   328 RSILRC 333
            |.::.|
  Rat   321 RQLVSC 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPBWR2	NP_005277.2	7tmA_NPBWR	46..327	CDD:320215	188/280 (67%)
		TM helix 1	47..73	CDD:320215	15/25 (60%)
		TM helix 2	80..106	CDD:320215	21/25 (84%)
		TM helix 3	117..147	CDD:320215	23/29 (79%)
		TM helix 4	161..183	CDD:320215	11/21 (52%)
		TM helix 5	209..238	CDD:320215	19/28 (68%)
		TM helix 6	253..283	CDD:320215	17/29 (59%)
		TM helix 7	295..320	CDD:320215	21/24 (88%)
Npbwr1	NP_001014784.1	7tmA_NPBWR	40..320	CDD:320215	188/280 (67%)
		TM helix 1	41..67	CDD:320215	15/25 (60%)
		TM helix 2	74..100	CDD:320215	21/25 (84%)
		TM helix 3	111..141	CDD:320215	23/29 (79%)
		TM helix 4	155..177	CDD:320215	11/21 (52%)
		TM helix 5	202..231	CDD:320215	19/28 (68%)
		TM helix 6	246..276	CDD:320215	17/29 (59%)
		TM helix 7	288..313	CDD:320215	21/24 (88%)