Protein Alignment CDH20 and cdh20

DIOPT Version :10

• Sequence 1: NP_114097.2
• Gene: CDH20 / 28316
• HGNCID: 1760
• Length: 801
• Species: Homo sapiens
• Sequence 2: XP_012820890.2
• Gene: cdh20 / 100498629
• XenbaseID: XB-GENE-1011620
• Length: 796
• Species: Xenopus tropicalis
• Alignment Length: 796
• Identity: 627/796 - (78%)
• Similarity: 702/796 - (88%)
• Gaps: 16/796 - (2%)

Human     6 RMSNAKNWLGLGMSLYFWGLMDLTTTVLSDTPTPQGELEALLSD--KPQSHQ----RTKRSWVWN 64
            |||..||:......:|:..|:|||..|...:       ..|:.|  ..||.|    |.|||||||
 Frog     6 RMSCKKNYHRHCALVYYMVLLDLTNAVFEFS-------HPLIRDSGNSQSRQLLPHRLKRSWVWN 63

Human    65 QFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGDIHAIQRLDREERAQ 129
            |||||||||||:||||||||||||.|||||||||||:|||.:|||||.|||||||||||||||:|
 Frog    64 QFFVLEEYTGTEPLYVGKLHSDMDNGDGSIKYILSGDGAGTMFTIDDGTGDIHAIQRLDREERSQ 128

Human   130 YTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADD 194
            ||||||||||.|.:|||||||||||||||||||||||||||.|:|.||||||||:|||:||||||
 Frog   129 YTLRAQALDRSTNKPMEPESEFIIKIQDINDNEPKFLDGPYTASVAEMSPVGTSIIQVSATDADD 193

Human   195 PTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTT 259
            ||||:||||||||||||||||||||||||||||.|||||::|||||||||||||||||||||||:
 Frog   194 PTYGSSARVVYSILQGQPYFSVDSKTGVIRTALTNMDRESREYYEVIIQAKDMGGQLGGLAGTTS 258

Human   260 VNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDI 324
            ||||||||||||||||||||||:||||:|::||||||.|.|||||:||||||:|:||||.:.|||
 Frog   259 VNITLSDVNDNPPRFPQKHYQMNVLESSPVNSTVGRVLAMDLDEGVNAEMKYSIIDGDGFEFFDI 323

Human   325 STDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVF 389
            .|||:.|||:|||||||.||:|||||||:||:|||||:||||||||:|||:||||||||||||||
 Frog   324 VTDPSNQVGVITVKKPLDFENKKSYTLKIEGSNPHLEIRFLNLGPFRDTTSVHISVEDVDEPPVF 388

Human   390 EPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDR 454
            |...|||||.|:|.|||||||:||||||.||||:||||||:|||||:||||:|||||||||||||
 Frog   389 ESNIYFVEVSENVDIGTTIQIVSAKDPDATNNSVRYSIDRNSDPGRYFYVDVTTGALMTARPLDR 453

Human   455 EEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVD 519
            ||.||||||:||||||||.|:|.||||||:||||||||.|.||||..:||||||.||||||||||
 Frog   454 EEVSWHNITILAMEMNNPKQIGGVPVTIKILDVNDNAPTFTRFYETLMCENAKADQLIQTVSAVD 518

Human   520 QDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVL 584
            ||||:.|||..||||||||||||||:||||||||.|||||:||:|.|||.|:||:||:|:|.|.|
 Frog   519 QDDPQEGQHISYSLAPEAANNPNFTLRDNQDNTALILTRRAGFKQSEQSTFYLPLLISDNGHPRL 583

Human   585 SSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHRKQP 649
            ||||||||||||||:||.:|||:.|.|.||:||||||||||||||||||||||||||||||||||
 Frog   584 SSTGTLTIQVCSCDEDGDIMSCNAEPYTLPISLSRGALIAILACIFVLLVLVLLILSMRRHRKQP 648

Human   650 YIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIESLSRYVPQ 714
            |.||:|:|:||||||||||||||||||||||||:|||||....   |||:||.||||||||||.|
 Frog   649 YTIDEEDNVHENIVRYDDEGGGEEDTEAFDIAALWNPREVHMA---KTRKDMKPEIESLSRYVTQ 710

Human   715 TCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTD 779
            :|.:::.||||:||||||||.|:.||||||||||||||:||||.|||||||.::|||||:|:|||
 Frog   711 SCRMDNNVHSYMLAKLYEADTDVCAPPFDSLQTYMFEGEGSVAQSLSSLQSLSTDSEQSYDYLTD 775

Human   780 WGPRFRKLAELYGASE 795
            |||||:||||:||..:
 Frog   776 WGPRFKKLAEMYGTKD 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDH20	NP_114097.2	CA	85..163	CDD:214520	68/77 (88%)
		Cadherin_repeat	169..270	CDD:206637	90/100 (90%)
		Cadherin_repeat	278..385	CDD:206637	83/106 (78%)
		Cadherin_repeat	394..490	CDD:206637	80/95 (84%)
		Cadherin_repeat	498..595	CDD:206637	76/96 (79%)
		CADH_Y-type_LIR	733..792	CDD:460041	46/58 (79%)
cdh20	XP_012820890.2	CA	84..162	CDD:214520	68/77 (88%)
		Cadherin_repeat	168..269	CDD:206637	90/100 (90%)
		Cadherin_repeat	277..384	CDD:206637	83/106 (78%)
		Cadherin_repeat	392..489	CDD:206637	80/96 (83%)
		Cadherin	497..594	CDD:394985	76/96 (79%)
		CADH_Y-type_LIR	729..788	CDD:460041	46/58 (79%)