DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OR4C13 and or5i1

DIOPT Version :9

Sequence 1:	NP_001001955.2	Gene:	OR4C13 / 283092	HGNCID:	15169	Length:	309	Species:	Homo sapiens
Sequence 2:	XP_031762372.1	Gene:	or5i1 / 100492617	XenbaseID:	XB-GENE-6032787	Length:	321	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	122/300 - (40%)
Similarity:	179/300 - (59%)	Gaps:	3/300 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     3 NRNNVTEFILLGLTENPKMQKIIFVVFSVIYINAMIGNVLIVVTITASPSLRSPMYFFLAYLSFI 67
            |.:...||||.||:|.|.:|.::|:||..|||..:|||:.::|....||:|::|||||||..||:
Frog     7 NHSTTREFILAGLSEIPDLQLLLFIVFLCIYIVTLIGNMFMIVAYKLSPNLQTPMYFFLANFSFL 71

Human    68 DACYSSVNTPKLITDSLYENKTILFNGCMTQVFGEHFFRGVEVILLTVMAYDHYVAICKPLHYTT 132
            :.||.|...||:::.....:|||..|||:.|:|......|.|..:|..||||.|||||.||.|..
Frog    72 EICYISSTVPKMLSGFTAGHKTISVNGCLVQMFFFLLLGGTECYMLASMAYDRYVAICHPLLYFN 136

Human   133 VMKQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPNVIDHFMCDLYTLINLACTNTHTLGLFI 197
            :|.:..|..|:..||:.|.:::.|..:....|.|||...||||.||:..|:.|||::|......:
Frog   137 IMNKGACIRLIVGSWLIGTVNSLIHTVLTFTLTFCGSTRIDHFYCDVPPLLKLACSDTWINETVL 201

Human   198 AANSGFICLLNCLLLLVSCVVILYS-LKTHSLEARHEALSTCVSHITVVILSFIPCIFVYMRPPA 261
            ....|.:.|.:.||.|.|..:|:.| |..|.:..|::..|||.||:.|||:.:....|:|.||..
Frog   202 HVMCGCVILGSFLLTLTSYTLIISSILNIHLISGRNKVFSTCSSHVMVVIIFYGSATFMYFRPKL 266

Human   262 TLPI--DKAVAVFYTMITSMLNPLIYTLRNAQMKNAIRKL 299
            :...  |:.:::.|.:|..:|||.||:|||.|:|:|:|||
Frog   267 SYGTGQDRFISIMYAVIAPLLNPFIYSLRNQQVKDAVRKL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OR4C13	NP_001001955.2	7tm_4	29..303	CDD:304433	109/273 (40%)
OR4C13	NP_001001955.2	7tm_1	39..285	CDD:278431	94/248 (38%)
or5i1	XP_031762372.1	7tmA_OR	27..296	CDD:320092	104/268 (39%)
		TM helix 1	29..53	CDD:320092	10/23 (43%)
		TM helix 2	62..84	CDD:320092	12/21 (57%)
		TM helix 3	100..122	CDD:320092	6/21 (29%)
		TM helix 4	145..161	CDD:320092	4/15 (27%)
		TM helix 5	198..221	CDD:320092	6/22 (27%)
		TM helix 6	240..262	CDD:320092	9/21 (43%)
		TM helix 7	271..296	CDD:320092	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910