DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OR4C13 and npsr1

DIOPT Version :9

Sequence 1:	NP_001001955.2	Gene:	OR4C13 / 283092	HGNCID:	15169	Length:	309	Species:	Homo sapiens
Sequence 2:	XP_031760328.1	Gene:	npsr1 / 100490145	XenbaseID:	XB-GENE-989267	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	310	Identity:	69/310 - (22%)
Similarity:	113/310 - (36%)	Gaps:	70/310 - (22%)

- Green bases have known domain annotations that are detailed below.

Human    20 KMQKIIFVVFSVIYINAMIGNVLIVVTITASPSLRSPMYFFLAYLSFIDACYSSVNTPKLITDSL 84
            ||:::|  ...:::|..:.||.:::.........:|.|.||:..|:..|.....:        |:
Frog    49 KMEQLI--TLWILFIVTIFGNSVVLYLTWKERKRKSRMTFFVTQLAITDYLTGII--------SI 103

Human    85 YENKTILFNG--------CMTQVFGEHFFRGVEVILLTVMAY-------DHYVAICKPLHYTTVM 134
            ..|....|.|        |.|       .|.::|:||....|       |.|.||..|:.:....
Frog   104 SVNIIWRFTGEFMAPEIVCKT-------VRYLQVVLLYASTYVLVSLSIDRYHAIVHPMKFLQGE 161

Human   135 KQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPN---------VIDHFMCDLYTLINLACTNT 190
            ||  ..:|:.|||...||.:....:...:|..  ||         ..|.:.....|::.|.   .
Frog   162 KQ--AKVLIAVSWTLSFLFSIPTFIIFGKLKL--PNGEMQCWALWPDDSYWTPYMTIVALL---V 219

Human   191 HTLGLFIAANSGFICLLNCLLLLVSCVVIL--YSLKTHSLEARHEALST-----CVSHITVVILS 248
            :.:.|.|.:...||.:....:......||:  |:.........|..|.:     .:.:..||||:
Frog   220 YFIPLIIISVIYFIVIRTIWVKSKGHAVIISNYTDGNFCTSYSHRGLISKAKMKAIKYSIVVILA 284

Human   249 FIPC-----IFVYMRPPATLPIDKAVAVFYT--------MITSMLNPLIY 285
            ||.|     :|..:.....||..|  ..||.        .:.|.:||:||
Frog   285 FILCWSPYFLFDILDNFEMLPETK--ERFYASVIIQHLPFLNSAINPIIY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OR4C13	NP_001001955.2	7tm_4	29..303	CDD:304433	66/301 (22%)
OR4C13	NP_001001955.2	7tm_1	39..285	CDD:278431	63/289 (22%)
npsr1	XP_031760328.1	7tmA_NPSR	51..341	CDD:320325	67/308 (22%)
		TM helix 1	52..76	CDD:320325	4/25 (16%)
		TM helix 2	85..108	CDD:320325	6/30 (20%)
		TM helix 3	123..145	CDD:320325	6/28 (21%)
		TM helix 4	166..182	CDD:320325	6/15 (40%)
		TM helix 5	209..232	CDD:320325	4/25 (16%)
		TM helix 6	275..297	CDD:320325	8/21 (38%)
		TM helix 7	311..336	CDD:320325	7/22 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910