DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OR4C13 and LOC100486033

DIOPT Version :9

Sequence 1:	NP_001001955.2	Gene:	OR4C13 / 283092	HGNCID:	15169	Length:	309	Species:	Homo sapiens
Sequence 2:	XP_017946459.1	Gene:	LOC100486033 / 100486033	-ID:	-	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	116/304 - (38%)
Similarity:	180/304 - (59%)	Gaps:	13/304 - (4%)

- Green bases have known domain annotations that are detailed below.

Human     3 NRNNVTEFILLGLTENPKMQKIIFVVFSVIYINAMIGNVLIVVTITASPSLRSPMYFFLAYLSFI 67
            |...||||.|.|.....::|.::|:||.:.|:..:..|::|:..|.....|..||:|||:.:||:
Frog     5 NETTVTEFFLRGFPTRLEIQILLFIVFLIAYVITVSENIMIITVIQLHSKLHKPMFFFLSNMSFL 69

Human    68 DACYSSVNTPKLITDSLYENKTILFNGCMTQVFGEHFFRGV---EVILLTVMAYDHYVAICKPLH 129
            :.||.||..|.|:..:|.:||:|.|:|||.|::   ||..:   |.:||.|||:|.|||:|.|||
Frog    70 EICYISVTLPNLLVSTLSKNKSISFSGCMAQLY---FFISLMCTECVLLAVMAFDRYVAVCHPLH 131

Human   130 YTTVMKQHVCSLLVGVSWVGGFLHATIQILFICQLPFCGPNVIDHFMCDLYTLINLACTNTHTLG 194
            |.|::...:|..|...||:.||..:.|::.||.:|.|||||:|:||.||:..::||||.:. :|.
Frog   132 YVTIISNKLCIQLAAASWIAGFTVSVIKVYFISRLSFCGPNIINHFFCDISPVLNLACEDM-SLA 195

Human   195 LFIAANSGFICLLNCLLLLVS---CVVILYSLKTHSLEARHEALSTCVSHITVVILSFIPCIFVY 256
            .|:......:.||..|.:.|:   |::... ||..:...|.:|.|||.||:|||.:.|...:|:|
Frog   196 EFVDFVLALVILLTPLFVTVASYLCIIFTI-LKIPTNTGRQKAFSTCASHLTVVTIFFSTTVFMY 259

Human   257 MRPPATLPID--KAVAVFYTMITSMLNPLIYTLRNAQMKNAIRK 298
            .||.....:|  |.:::.|.:.|.|:||.||..||.::...::|
Frog   260 ARPKKAKSLDYFKLLSLLYAVFTPMMNPFIYCFRNKEIWGTLKK 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OR4C13	NP_001001955.2	7tm_4	29..303	CDD:304433	106/278 (38%)
OR4C13	NP_001001955.2	7tm_1	39..285	CDD:278431	99/253 (39%)
LOC100486033	XP_017946459.1	7tmA_OR6B-like	25..294	CDD:320352	105/273 (38%)
		TM helix 1	26..52	CDD:320352	7/25 (28%)
		TM helix 2	59..85	CDD:320352	12/25 (48%)
		TM helix 3	97..127	CDD:320352	15/32 (47%)
		TM helix 4	141..159	CDD:320352	6/17 (35%)
		TM helix 5	195..225	CDD:320352	6/29 (21%)
		TM helix 6	232..262	CDD:320352	13/29 (45%)
		TM helix 7	269..294	CDD:320352	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910